Sfoglia per Autore
Synthesis of 3beta,7alpha-Dihydroxy-Δ5-cholenoic Acid Derivatives: ‘Atypical’ Bile Acid Metabolites and Useful Biomarkers to Detect 3delta-HSDH Deficiency
2013 Gioiello, Antimo; Cerra, B.; Setchell, K. D.; Pellicciari, R.
Application of Untargeted and Targeted Metabolomics to the Study of Liver Disease Caused by a Deficiency in HSD3B7-diagnosis and Response to Therapy
2014 Zhang, W.; Wolfe, B.; Jha, P.; Gioiello, Antimo; Cerra, B.; Villarini, G.; Pellicciari, Roberto; Setchell, K. D.
Synthesis of atypical bile acids for use as investigative tools for the genetic defect of 3b-hydroxy-Δ5-C27-steroid oxidoreductase deficiency
2014 Gioiello, Antimo; Cerra, B.; Zhang, W.; Vallerini, G. P.; Costantino, G.; De Franco, F.; Passeri, D.; Pellicciari, R.; Setchell, K. D. R.
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands
2014 Carotti, Andrea; Marinozzi, Maura; Custodi, Chiara; Cerra, Bruno; Pellicciari, Roberto; Gioiello, Antimo; Macchiarulo, Antonio
Bile Acid Derivatives as Ligands of the Farnesoid X Receptor: Molecular Determinants for Bile Acid Binding and Receptor Modulation
2014 Gioiello, Antimo; Cerra, B.; Mostarda, S.; Guercini, C.; Pellicciari, R.; Macchiarulo, Antonio
First total synthesis of piperenol B and configuration revision of the enantiomers piperenol B and uvarirufol A
2015 Fischer, T. C.; Cerra, B.; Fink, M. J.; Rudroff, F.; Horkel, E.; Mihovilovic, M. D.
IDENTIFICATION OF A NOVEL CLASS OF PREGNANE X RECEPTOR (PXR) LIGANDS: FLOW SYNTHESIS AND PRELIMINARY BIOLOGICAL ACTIVITY OF TETRAHYDROQUINOLINES
2016 Cerra, Bruno; Mancino, Valentina; Passeri, Daniela; De Franco, Francesca; Macchiarulo, Antonio; Pellicciari, Roberto; Gioiello, Antimo
ATYPICAL BILE ACIDS AS CHEMICAL PROBES FOR DIAGNOSIS AND THERAPHY MONITORING OF PROGRESSIVE CHOLESTATIC LIVER DISEASE IN HSD3B7 PATIENTS
2016 Gioiello, Antimo; Cerra, Bruno; Zhang, Wujuan; Pellicciari, Roberto; Setchell, Kenneth D. R.
Speeding up Early Phases of Drug Discovery: DoE-Driven Synthetic Optimization of Chemical Processes in Flow Systems
2016 Gioiello, Antimo; Mostarda, Serena; Cerra, Bruno; Mancino, Valentina; Filipponi, Paolo; Pellicciari, Roberto
Concepts and Optimization Strategies of Experimental Design in Continuous-Flow Processing
2016 Gioiello, Antimo; Mancino, Valentina; Filipponi, Paolo; Mostarda, Serena; Cerra, Bruno
Integrating Multicomponent Flow Synthesis and Computational Approaches for the Generation of a Tetrahydroquinoline Compound Based Library
2016 Cerra, Bruno; Mostarda, Serena; Custodi, Chiara; Macchiarulo, Antonio; Gioiello, Antimo
Synthesis of hydroxy lactones by selenium-mediated oxidation/cyclization of alkenoic acids under eco-flow conditions
2017 Cerra, Bruno; Mangiavacchi, Francesca; Santi, Claudio; Lozza, ANNA MARIA; Mancino, Valentina; Gioiello, Antimo
9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR)
2017 Gioiello, Antimo; Marinozzi, Maura; Cerra, Bruno; Custodi, Chiara; Pellicciari, Roberto; Macchiarulo, Antonio
Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells
2017 Gatticchi, Leonardo; Cerra, Bruno; Scarpelli, Paolo; Macchioni, Lara; Sebastiani, Bartolomeo; Gioiello, Antimo; Roberti, Rita
Selective continuous flow synthesis of hydroxy lactones from alkenoic acids
2017 Cerra, B.; Mangiavacchi, F.; Santi, C.; Lozza, A. M.; Gioiello, A.
Development of a Continuous Flow Synthesis of 16-Dehydropregnenolone Acetate: A Powered Entry into Steroids from Plants
2018 Mancino, V; Piccinno, P; Lozza, A M; Cerra, B; Gioiello, A
Continuous Flow Synthesis and Enzymatic Resolution of 3-Hydroxy-ɣ-Butyrolactone (3-BHL): A Key Building Block for Synthesis and Drugs
2018 Lozza, A M; Blasi, F; Cerra, B; Tali, S S; Cossignani, L; Gioiello, A
Continuous Flow Synthesis of 16-Dehydropregnenolone Acetate, a Key Synthon for Natural Steroids and Drugs
2018 Mancino, V; Cerra, B; Piccinno, A; Gioiello, A
BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects
2018 Venturoni, Francesco; Cerra, Bruno; Marinozzi, Maura; Camaioni, Emidio; Gioiello, Antimo; Pellicciari, Roberto
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification
2018 Mostarda, Serena; Passeri, Daniela; Carotti, Andrea; Cerra, Bruno; Colliva, Carolina; Benicchi, Tiziana; Macchiarulo, Antonio; Pellicciari, Roberto; Gioiello, Antimo
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