Abstract: The efficacy and tolerability of taurine (3 g daily) in the treatment of intermittent claudication were evaluated in a double-blind placebo-controlled study in 40 patients. Before therapy and after 3 and 6 months, besides standard treadmill exercise walking times, ankle/arm pressure ratios, plethysmographic peak flow values, transcutaneous oxygen pressure (TcPO2) was also monitored on the dorsum of the foot in basal conditions together with the half-recovery times after an induced ischemia. Taurine was more beneficial than placebo in lengthening the pain-free and total walking times and significantly shortened TcPO2 half-recovery time. These results suggest that taurine not only improves performance in patients with intermittent claudication but also increases oxygenation in the ischemic limbs

TAURINE THERAPY FOR INTERMITTENT CLAUDICATION - RESULTS OF A CONTROLLED-STUDY

PASQUALINI, Leonella;VAUDO, Gaetano;CIUFFETTI, Giovanni;MANNARINO, Elmo
1993

Abstract

Abstract: The efficacy and tolerability of taurine (3 g daily) in the treatment of intermittent claudication were evaluated in a double-blind placebo-controlled study in 40 patients. Before therapy and after 3 and 6 months, besides standard treadmill exercise walking times, ankle/arm pressure ratios, plethysmographic peak flow values, transcutaneous oxygen pressure (TcPO2) was also monitored on the dorsum of the foot in basal conditions together with the half-recovery times after an induced ischemia. Taurine was more beneficial than placebo in lengthening the pain-free and total walking times and significantly shortened TcPO2 half-recovery time. These results suggest that taurine not only improves performance in patients with intermittent claudication but also increases oxygenation in the ischemic limbs
1993
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1092473
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