A new, improved procedure for the preparation of phosphonium halide on route to 3-(alkenyl)cephem derivatives is described. The approach involves the on-pot reaction of the 3-hydroxymethyl cephem derivative with methyltriphenoxyphosphonium iodide in dichloromethane.
An Improved Procedure for the Preparation of a 3-(Alkenyl) Cephem Derivative
CURINI, Massimo;ROSATI, Ornelio;
1997
Abstract
A new, improved procedure for the preparation of phosphonium halide on route to 3-(alkenyl)cephem derivatives is described. The approach involves the on-pot reaction of the 3-hydroxymethyl cephem derivative with methyltriphenoxyphosphonium iodide in dichloromethane.File in questo prodotto:
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