New Planar and Centrally Chiral Sulfinylcyclophanes

In this communication we intend to report a revisited and more efficient approach to the same kind of bis-bridged thicyclophane (thiaCPs) S-oxide but showing both planar and central chirality. The cage skeleton of thiaCPs (figure), with the co-existence of two different source of chirality such as the chiral sulfinyl groups and the planar chirality, obtained with the introduction of two methyl groups on both side of one of the rings, represents a new stimulating model system to deepen the structure/chirality relashionship of this kind of molecules. Otherwise, the revised synthetic methodology guarantees higher yields with respect to previous reported procedures