In an experimental model using dendritic cells and synthetic tumor peptides to induce antitumor protection, interleukin 12 exerts potent immunoadjuvant effects, including regulatory functions on both dendritic cells and antigen-specific CD4+ cells. These data offer useful information for developing vaccination strategies using dendritic cells and tumor peptides in humans
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy
GROHMANN, Ursula;BIANCHI, Roberta;BELLADONNA, Maria Laura;ORABONA, Ciriana;VACCA, Carmine;
1998
Abstract
In an experimental model using dendritic cells and synthetic tumor peptides to induce antitumor protection, interleukin 12 exerts potent immunoadjuvant effects, including regulatory functions on both dendritic cells and antigen-specific CD4+ cells. These data offer useful information for developing vaccination strategies using dendritic cells and tumor peptides in humansFile in questo prodotto:
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