Lipodystrophy is one of the most common complications of subcutaneous insulin therapy and may present as either lipo-atrophy (atrophy and fibrosis of subcutaneous fat) or lipo-hypertrophy (localized increase in volume and consistency of subcutaneous fat) at the insulin injection sites. An inadequate injection technique is usually considered the main risk factor for lipodystrophies, which may cause inexplicable glycemic oscillations, and hyper- or hypoglycemias. This review summarizes the pathophysiology, biological profile and clinical features of insulin injection-associated lipodystrophies in diabetic patients, aiming to promote educational strategies in patients and diabetes operators for the correct identification and prevention of the disorder.

Awareness, identification and prevention of insulin injection-associated lipodystrophies

Porcellati F.;
2016

Abstract

Lipodystrophy is one of the most common complications of subcutaneous insulin therapy and may present as either lipo-atrophy (atrophy and fibrosis of subcutaneous fat) or lipo-hypertrophy (localized increase in volume and consistency of subcutaneous fat) at the insulin injection sites. An inadequate injection technique is usually considered the main risk factor for lipodystrophies, which may cause inexplicable glycemic oscillations, and hyper- or hypoglycemias. This review summarizes the pathophysiology, biological profile and clinical features of insulin injection-associated lipodystrophies in diabetic patients, aiming to promote educational strategies in patients and diabetes operators for the correct identification and prevention of the disorder.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1493754
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