Enantiomerically pure 2,3.5-trisubstituted morpholines with two newly created stereocenters have been prepared by a short synthetic sequence having as the key step the selenium-promoted addition of (R)-phenylglycinol to a substituted alkene.
Selenium-Promoted Synthesis of Enantiomerically Pure Substituted Morpholines Starting from Alkenes and Chiral Aminoalcohols
TIECCO, Marcello;TESTAFERRI, Lorenzo;MARINI, Francesca;STERNATIVO, Silvia;SANTI, Claudio;BAGNOLI, Luana;TEMPERINI, Andrea
2003
Abstract
Enantiomerically pure 2,3.5-trisubstituted morpholines with two newly created stereocenters have been prepared by a short synthetic sequence having as the key step the selenium-promoted addition of (R)-phenylglycinol to a substituted alkene.File in questo prodotto:
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