Recently, we reported the recent isolation and structure elucidation of leucinostatin D, a minor, biologically active, peptide component of the antibiotic mixture produced by submerged cultures of Paecilomyces marquandii (Massee) Hughes. In a search for further biologically active metabolites, the dark-brownish oily resude from the benzene extract of the culture broth was subjected to repeated flash chromatography on silica gel column.
Leucinostatins H and K, two novel peptide antibiotics with tertiary amine-oxide terminal group from Paecilomyces marquandii. Isolation, structure, and biological activity
ROSSI, Carlo;RICCI, Maurizio;
1987
Abstract
Recently, we reported the recent isolation and structure elucidation of leucinostatin D, a minor, biologically active, peptide component of the antibiotic mixture produced by submerged cultures of Paecilomyces marquandii (Massee) Hughes. In a search for further biologically active metabolites, the dark-brownish oily resude from the benzene extract of the culture broth was subjected to repeated flash chromatography on silica gel column.File in questo prodotto:
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