Sfoglia per Autore
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL
2009 Roti, Giovanni; K. N., Ross; A. A., Ferrando; S. C., Blacklow; J., Aster; K., Stegmaier
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
2010 Aste Amézaga, M; Zhang, N; Lineberger, Je; Arnold, Ba; Toner, Tj; Gu, M; Huang, L; Vitelli, S; Vo, Kt; Haytko, P; Zhao, Jz; Baleydier, F; L'Heureux, S; Wang, H; Gordon, Wr; Thoryk, E; Andrawes, Mb; Tiyanont, K; Stegmaier, K; Roti, Giovanni; Ross, Kn; Franlin, Ll; Wang, H; Wang, F; Chastain, M; Bett, Aj; Audoly, Lp; Aster, Jc; Blacklow, Sc; Huber, He
Targeting NOTCH1 in hematopoietic malignancy.
2011 Roti, Giovanni; Stegmaier, K.
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies
2011 Roti, Giovanni; A., Carlton; K. N., Ross; M., Markstein; K., Pajcini; N., Perrimon; A. L., Kung; W. S., Pear; S. C., Blacklow; J. C., Aster; K., Stegmaier
Genetic and proteomic approaches to identify cancer drug targets.
2012 Roti, Giovanni; Stegmaier, K.
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.
2012 Banerji, V; Frumm, Sm; Ross, Kn; Li, Ls; Schinzel, Ac; Hahn, Ck; Kakoza, Rm; Chow, Kt; Ross, L; Alexe, G; Tolliday, N; Inguilizian, H; Galinsky, I; Stone, Rm; Deangelo, Dj; Roti, Giovanni; Aster, Jc; Hahn, Wc; Kung, Al; Stegmaier, K.
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.
2013 Frumm, Sm; Fan, Zp; Ross, Kn; Duvall, Jr; Gupta, S; Verplank, L; Suh, Bc; Holson, E; Wagner, Ff; Smith, Wb; Paranal, Rm; Bassil, Cf; Qi, J; Roti, Giovanni; Kung, Al; Bradner, Je; Tolliday, N; Stegmaier, K.
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
2013 Roti, Giovanni; Carlton, A; Ross, Kn; Markstein, M; Pajcini, K; Su, Ah; Perrimon, N; Pear, Ws; Kung, Al; Blacklow, Sc; Aster, Jc; Stegmaier, K.
New Approaches to Target T-ALL
2014 Roti, Giovanni; Kimberly, Stegmaier
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY
2015 Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo
2016 Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia
2018 Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P.
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin
2018 La Starza, Roberta; Pierini, Tiziana; Pastorino, Lorenza; Albi, Elisa; Matteucci, Caterina; Crescenzi, Barbara; Sportoletti, Paolo; Covarelli, Piero; Falzetti, Franca; Roti, Giovanni; Ascani, Stefano; Mecucci, Cristina
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement
2018 la Starza, Roberta; Messina, Monica; Gianfelici, Valentina; Pierini, Valentina; Matteucci, Caterina; Pierini, Tiziana; Limongi, Maria Zaira; Vitale, Antonella; Roti, Giovanni; Chiaretti, Sabina; Foà, Robin; Mecucci, Cristina
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes.
2019 LEMA FERNANDEZ, ANAIR GRACIELA; Crescenzi, Barbara; Pierini, Valentina; DI BATTISTA, Valeria; Barba, Gianluca; Pellanera, Fabrizia; DI GIACOMO, Danika; Roti, Giovanni; Rocco, Piazza; Adelman, Emmalee R.; Figueroa, MARIA EUGENIA; Mecucci, Cristina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL | 2009 | Roti, Giovanni; K. N., Ross; A. A., Ferrando; S. C., Blacklow; J., Aster; K., Stegmaier | |
| Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. | 2010 | Aste Amézaga, M; Zhang, N; Lineberger, Je; Arnold, Ba; Toner, Tj; Gu, M; Huang, L; Vitelli, S; Vo, Kt; Haytko, P; Zhao, Jz; Baleydier, F; L'Heureux, S; Wang, H; Gordon, Wr; Thoryk, E; Andrawes, Mb; Tiyanont, K; Stegmaier, K; Roti, Giovanni; Ross, Kn; Franlin, Ll; Wang, H; Wang, F; Chastain, M; Bett, Aj; Audoly, Lp; Aster, Jc; Blacklow, Sc; Huber, He | |
| Targeting NOTCH1 in hematopoietic malignancy. | 2011 | Roti, Giovanni; Stegmaier, K. | |
| Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies | 2011 | Roti, Giovanni; A., Carlton; K. N., Ross; M., Markstein; K., Pajcini; N., Perrimon; A. L., Kung; W. S., Pear; S. C., Blacklow; J. C., Aster; K., Stegmaier | |
| Genetic and proteomic approaches to identify cancer drug targets. | 2012 | Roti, Giovanni; Stegmaier, K. | |
| The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. | 2012 | Banerji, V; Frumm, Sm; Ross, Kn; Li, Ls; Schinzel, Ac; Hahn, Ck; Kakoza, Rm; Chow, Kt; Ross, L; Alexe, G; Tolliday, N; Inguilizian, H; Galinsky, I; Stone, Rm; Deangelo, Dj; Roti, Giovanni; Aster, Jc; Hahn, Wc; Kung, Al; Stegmaier, K. | |
| Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. | 2013 | Frumm, Sm; Fan, Zp; Ross, Kn; Duvall, Jr; Gupta, S; Verplank, L; Suh, Bc; Holson, E; Wagner, Ff; Smith, Wb; Paranal, Rm; Bassil, Cf; Qi, J; Roti, Giovanni; Kung, Al; Bradner, Je; Tolliday, N; Stegmaier, K. | |
| Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. | 2013 | Roti, Giovanni; Carlton, A; Ross, Kn; Markstein, M; Pajcini, K; Su, Ah; Perrimon, N; Pear, Ws; Kung, Al; Blacklow, Sc; Aster, Jc; Stegmaier, K. | |
| New Approaches to Target T-ALL | 2014 | Roti, Giovanni; Kimberly, Stegmaier | |
| IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY | 2015 | Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F | |
| BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo | 2016 | Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P | |
| Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia | 2018 | Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P. | |
| Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin | 2018 | La Starza, Roberta; Pierini, Tiziana; Pastorino, Lorenza; Albi, Elisa; Matteucci, Caterina; Crescenzi, Barbara; Sportoletti, Paolo; Covarelli, Piero; Falzetti, Franca; Roti, Giovanni; Ascani, Stefano; Mecucci, Cristina | |
| High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement | 2018 | la Starza, Roberta; Messina, Monica; Gianfelici, Valentina; Pierini, Valentina; Matteucci, Caterina; Pierini, Tiziana; Limongi, Maria Zaira; Vitale, Antonella; Roti, Giovanni; Chiaretti, Sabina; Foà, Robin; Mecucci, Cristina | |
| A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. | 2019 | LEMA FERNANDEZ, ANAIR GRACIELA; Crescenzi, Barbara; Pierini, Valentina; DI BATTISTA, Valeria; Barba, Gianluca; Pellanera, Fabrizia; DI GIACOMO, Danika; Roti, Giovanni; Rocco, Piazza; Adelman, Emmalee R.; Figueroa, MARIA EUGENIA; Mecucci, Cristina |
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