VARASANO, EMANUELA
VARASANO, EMANUELA
DIPARTIMENTO DI MEDICINA (attivo dal 01/01/2014 al 31/10/2020)
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia
2018 Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P.
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo
2016 Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P
Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults
2010 Gorello, Paolo; LA STARZA, Roberta; Varasano, Emanuela; Chiaretti, S; Elia, L; Pierini, Valentina; Barba, Gianluca; Brandimarte, Lucia; Crescenzi, Barbara; Vitale, A; Messina, M; Grammatico, S; Mancini, M; Matteucci, Caterina; Bardi, A; Guarini, A; Martelli, Massimo Fabrizio; Foà, R; Mecucci, Cristina
Comparative genomic hybridization identifies 17q11.2 approximately q12 duplication as an early event in cutaneous T-cell lymphomas
2008 Barba, Gianluca; Matteucci, Caterina; Girolomoni, G.; Brandimarte, Lucia; Varasano, Emanuela; Martelli, Massimo Fabrizio; Mecucci, Cristina
GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations
2019 Sportoletti, P; Celani, L; Varasano, E; Rossi, R; Sorcini, D; Rompietti, C; Strozzini, F; Del Papa, B; Guarente, Valerio; Spinozzi, Giulio; Cecchini, D; Bereshchenko, O; Haferlach, T; Martelli, Mp; Falzetti, F; Falini, B
Identification and Characterization of Novel Rare Nucleophosmin (NPM1) Gene Mutations in Acute Myeloid Leukemia (AML) By a Combinatorial Approach of Immunohistochemistry and Molecular Analyses
2016 Martelli, Maria Paola; Rossi, Roberta; Varasano, Emanuela; Specchia, G; Di Raimondo, F; Avvisati, G; Tiacci, Enrico; Falzetti, Franca; Sportoletti, Paolo; Falini, Brunangelo
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY
2015 Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F
Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications
2015 Sportoletti, Paolo; Varasano, Emanuela; Rossi, R; Mupo, A; Tiacci, Enrico; Vassiliou, G; Martelli, Maria Paola; Falini, Brunangelo
NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells.
2018 Di Ianni, M; Baldoni, S; Del Papa, B; Aureli, Patrizia; Dorillo, Erica; De Falco, F; Albi, Elisa; Varasano, E; Di Tommaso, A; Giancola, R; Accorsi, P; Rotta, G; Rompietti, Chiara; SILVA BARCELOS, ESTEVAO CARLOS; Campese, Af; Di Bartolomeo, P; Screpanti, I; Rosati, E; Falzetti, F; Sportoletti, P
Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML
2021 Martelli, M. P.; Rossi, R.; Venanzi, A.; Meggendorfer, M.; Perriello, V. M.; Martino, G.; Spinelli, O.; Ciurnelli, R.; Varasano, E.; Brunetti, L.; Ascani, S.; Quadalti, C.; Cardinali, V.; Mezzasoma, F.; Gionfriddo, I.; Milano, F.; Pacini, R.; Tabarrini, A.; Bigerna, B.; Albano, F.; Specchia, G.; Vetro, C.; Di Raimondo, F.; Annibali, O.; Avvisati, G.; Rambaldi, A.; Falzetti, F.; Tiacci, E.; Sportoletti, P.; Haferlach, T.; Haferlach, C.; Falini, B.
NPM1 AND FLT3-ITD MUTATIONS COOPERATE TO IMPAIR HEMATOPOIETIC STEM/PROGENITOR CELLS DIFFERENTIATION AND DEREGULATE GATA1 IN A MOUSE MODEL OF AML
2014 Sportoletti, Paolo; Varasano, Emanuela; Rossi, Roberta; Celani, Letizia; Rompietti, Chiara; Strozzini, Francesca; Proietti, A. Alunni; DEL PAPA, Beatrice; Bonifacio, E.; Bereshchenko, Oxana; Martelli, Maria Paola; Falzetti, Franca; Falini, Brunangelo
NPM1 AND FLT3-ITD MUTATIONS SINERGISTICALLY INDUCE GATA1 EPIGENETIC SILENCING IN A AML MOUSE MODEL
2016 Sportoletti, Paolo; Varasano, Emanuela; Celani, Letizia; Rossi, Roberta; Rompietti, Chiara; Strozzini, Francesca; DEL PAPA, Beatrice; Cecchini, Debora; Bereshchenko, Oxana; Haferlach, T.; Martelli, Maria Paola; Falzetti, Franca; Falini, Brunangelo
Rescue of genomic information in adult acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics: a GIMEMA centralized biological study
2010 Matteucci, Caterina; Barba, Gianluca; Varasano, Emanuela; Vitale, A; Mancini, M; Testoni, N; Cuneo, A; REGE CAMBRIN, G; Elia, L; LA STARZA, Roberta; Pierini, V; Brandimarte, Lucia; Vignetti, M; Foà, R; Mecucci, Cristina; GIMEMA ACUTE LEUKAEMIA WORKING, Party
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
2013 Sportoletti, Paolo; Varasano, Emanuela; Rossi, Roberta; Bereshchenko, Oxana; Cecchini, Debora; Gionfriddo, Ilaria; Bolli, Niccolo'; Tiacci, Enrico; Intermesoli, T; Zanghì, P; Masciulli, A; Martelli, Maria Paola; Falzetti, Franca; Martelli, Massimo Fabrizio; Falini, Brunangelo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia | 2018 | Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P. | |
| BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo | 2016 | Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P | |
| Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults | 2010 | Gorello, Paolo; LA STARZA, Roberta; Varasano, Emanuela; Chiaretti, S; Elia, L; Pierini, Valentina; Barba, Gianluca; Brandimarte, Lucia; Crescenzi, Barbara; Vitale, A; Messina, M; Grammatico, S; Mancini, M; Matteucci, Caterina; Bardi, A; Guarini, A; Martelli, Massimo Fabrizio; Foà, R; Mecucci, Cristina | |
| Comparative genomic hybridization identifies 17q11.2 approximately q12 duplication as an early event in cutaneous T-cell lymphomas | 2008 | Barba, Gianluca; Matteucci, Caterina; Girolomoni, G.; Brandimarte, Lucia; Varasano, Emanuela; Martelli, Massimo Fabrizio; Mecucci, Cristina | |
| GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations | 2019 | Sportoletti, P; Celani, L; Varasano, E; Rossi, R; Sorcini, D; Rompietti, C; Strozzini, F; Del Papa, B; Guarente, Valerio; Spinozzi, Giulio; Cecchini, D; Bereshchenko, O; Haferlach, T; Martelli, Mp; Falzetti, F; Falini, B | |
| Identification and Characterization of Novel Rare Nucleophosmin (NPM1) Gene Mutations in Acute Myeloid Leukemia (AML) By a Combinatorial Approach of Immunohistochemistry and Molecular Analyses | 2016 | Martelli, Maria Paola; Rossi, Roberta; Varasano, Emanuela; Specchia, G; Di Raimondo, F; Avvisati, G; Tiacci, Enrico; Falzetti, Franca; Sportoletti, Paolo; Falini, Brunangelo | |
| IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY | 2015 | Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F | |
| Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications | 2015 | Sportoletti, Paolo; Varasano, Emanuela; Rossi, R; Mupo, A; Tiacci, Enrico; Vassiliou, G; Martelli, Maria Paola; Falini, Brunangelo | |
| NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells. | 2018 | Di Ianni, M; Baldoni, S; Del Papa, B; Aureli, Patrizia; Dorillo, Erica; De Falco, F; Albi, Elisa; Varasano, E; Di Tommaso, A; Giancola, R; Accorsi, P; Rotta, G; Rompietti, Chiara; SILVA BARCELOS, ESTEVAO CARLOS; Campese, Af; Di Bartolomeo, P; Screpanti, I; Rosati, E; Falzetti, F; Sportoletti, P | |
| Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML | 2021 | Martelli, M. P.; Rossi, R.; Venanzi, A.; Meggendorfer, M.; Perriello, V. M.; Martino, G.; Spinelli, O.; Ciurnelli, R.; Varasano, E.; Brunetti, L.; Ascani, S.; Quadalti, C.; Cardinali, V.; Mezzasoma, F.; Gionfriddo, I.; Milano, F.; Pacini, R.; Tabarrini, A.; Bigerna, B.; Albano, F.; Specchia, G.; Vetro, C.; Di Raimondo, F.; Annibali, O.; Avvisati, G.; Rambaldi, A.; Falzetti, F.; Tiacci, E.; Sportoletti, P.; Haferlach, T.; Haferlach, C.; Falini, B. | |
| NPM1 AND FLT3-ITD MUTATIONS COOPERATE TO IMPAIR HEMATOPOIETIC STEM/PROGENITOR CELLS DIFFERENTIATION AND DEREGULATE GATA1 IN A MOUSE MODEL OF AML | 2014 | Sportoletti, Paolo; Varasano, Emanuela; Rossi, Roberta; Celani, Letizia; Rompietti, Chiara; Strozzini, Francesca; Proietti, A. Alunni; DEL PAPA, Beatrice; Bonifacio, E.; Bereshchenko, Oxana; Martelli, Maria Paola; Falzetti, Franca; Falini, Brunangelo | |
| NPM1 AND FLT3-ITD MUTATIONS SINERGISTICALLY INDUCE GATA1 EPIGENETIC SILENCING IN A AML MOUSE MODEL | 2016 | Sportoletti, Paolo; Varasano, Emanuela; Celani, Letizia; Rossi, Roberta; Rompietti, Chiara; Strozzini, Francesca; DEL PAPA, Beatrice; Cecchini, Debora; Bereshchenko, Oxana; Haferlach, T.; Martelli, Maria Paola; Falzetti, Franca; Falini, Brunangelo | |
| Rescue of genomic information in adult acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics: a GIMEMA centralized biological study | 2010 | Matteucci, Caterina; Barba, Gianluca; Varasano, Emanuela; Vitale, A; Mancini, M; Testoni, N; Cuneo, A; REGE CAMBRIN, G; Elia, L; LA STARZA, Roberta; Pierini, V; Brandimarte, Lucia; Vignetti, M; Foà, R; Mecucci, Cristina; GIMEMA ACUTE LEUKAEMIA WORKING, Party | |
| The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model. | 2013 | Sportoletti, Paolo; Varasano, Emanuela; Rossi, Roberta; Bereshchenko, Oxana; Cecchini, Debora; Gionfriddo, Ilaria; Bolli, Niccolo'; Tiacci, Enrico; Intermesoli, T; Zanghì, P; Masciulli, A; Martelli, Maria Paola; Falzetti, Franca; Martelli, Massimo Fabrizio; Falini, Brunangelo |