BRUNETTI, LORENZO
BRUNETTI, LORENZO
Dipartimento di Medicina e Chirurgia
A venetoclax and azacitidine bridge-to-transplant strategy for NPM1-mutated acute myeloid leukaemia in molecular failure
2023 Sartor, C; Brunetti, L; Audisio, E; Cignetti, A; Zannoni, L; Cristiano, G; Nanni, J; Ciruolo, R; Zingarelli, F; Ottaviani, E; Patuelli, A; Bandini, L; Forte, D; Sciabolacci, S; Cardinali, V; Papayannidis, C; Cavo, M; Martelli, M P; Curti, A
Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss
2019 Colleluori, G.; Aguirre, L.; Phadnis, U.; Fowler, K.; Armamento-Villareal, R.; Sun, Z.; Brunetti, L.; Hyoung Park, J.; Kaipparettu, B. A.; Putluri, N.; Auetumrongsawat, V.; Yarasheski, K.; Qualls, C.; Villareal, D. T.
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
2015 Martelli, Maria Paola; Gionfriddo, Ilaria; Mezzasoma, Federica; Milano, Francesca; Pierangeli, Sara; Mulas, Floriana; Pacini, Roberta; Tabarrini, Alessia; Pettirossi, Valentina; Rossi, Roberta; Vetro, Calogero; Brunetti, Lorenzo; Sportoletti, Paolo; Tiacci, Enrico; Di Raimondo, Francesco; Falini, Brunangelo
ARSENIC TRIOXIDE AND ALL-TRANS-RETINOIC ACID TARGET NPM1 MUTANT ONCOPROTEIN LEVELS AND INDUCE APOPTOSIS IN NPM1-MUTATED AML CELLS
2015 Martelli, Maria Paola; Gionfriddo, Ilaria; Mezzasoma, Federica; Milano, Francesca; Pierangeli, Sara; Pettirossi, Valentina; Rossi, R.; Strozzini, Francesca; Vetro, C.; Brunetti, L.; Sportoletti, Paolo; Tiacci, Enrico; Di Raimondo, F.; Falini, Brunangelo
Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice
2020 Sportoletti, Paolo; Sorcini, Daniele; Guzman, Anna G; Reyes, Jaime M; Stella, Arianna; Marra, Andrea; Sartori, Sara; Brunetti, Lorenzo; Rossi, Roberta; Papa, Beatrice Del; Adamo, Francesco Maria; Pianigiani, Giulia; Betti, Camilla; Scialdone, Annarita; Guarente, Valerio; Spinozzi, Giulio; Tini, Valentina; Martelli, Maria Paola; Goodell, Margaret A; Falini, Brunangelo
Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin
2017 Brunetti, L; Di Battista, V; Venanzi, A; Schiavoni, G; Martelli, M. P.; Ascani, S; Mecucci, C; Tiacci, E; Falini, B
CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression
2020 Fousek, Kristen; Watanabe, Junji; Joseph, Sujith K; George, Ann; An, Xingyue; Byrd, Tiara T; Morris, Jessica S; Luong, Annie; Martínez-Paniagua, Melisa A; Sanber, Khaled; Navai, Shoba A; Gad, Ahmed Z; Salsman, Vita S; Mathew, Pretty R; Kim, Hye Na; Wagner, Dimitrios L; Brunetti, Lorenzo; Jang, Albert; Baker, Matthew L; Varadarajan, Navin; Hegde, Meenakshi; Kim, Yong-Mi; Heisterkamp, Nora; Abdel-Azim, Hisham; Ahmed, Nabil
CD123 (IL-3R alpha) IS CONSISTENTLY EXPRESSED ON ACUTE MYELOID LEUKEMIA (AML) CARRYING NUCLEOPHOSMIN (NPM1) GENE MUTATION
2014 Brunetti, Lorenzo; Gionfriddo, Ilaria; Rossi, Roberta; Mezzasoma, Federica; Milano, Francesca; Vetro, C.; Di Raimondo, F.; Falini, Brunangelo; Martelli, Maria Paola
CD123 Is Consistently Expressed on NPM1-Mutated AML Cells
2021 Perriello, V. M.; Gionfriddo, I.; Rossi, R.; Milano, F.; Mezzasoma, F.; Marra, A.; Spinelli, O.; Rambaldi, A.; Annibali, O.; Avvisati, G.; Di Raimondo, F.; Ascani, S.; Falini, B.; Martelli, M. P.; Brunetti, L.
CD200/OX2, a cell surface molecule with immuno-regulatory function, is consistently expressed on hairy cell leukaemia neoplastic cells: Correspondence
2009 Brunetti, L.; Di Noto, R.; Abate, G.; Gorrese, M.; Gravetti, A.; Raia, M.; Scalia, G.; Pascariello, C.; Camera, A.; Del Vecchio, L.
CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.
2010 Martelli, Maria Paola; Pettirossi, Valentina; Thiede, C; Bonifacio, E; Mezzasoma, F; Cecchini, D; Pacini, R; Tabarrini, A; Ciurnelli, R; Gionfriddo, I; Manes, N; Rossi, R; Giunchi, L; Oelschlägel, U; Brunetti, L; Gemei, M; Delia, M; Specchia, G; Liso, A; Di Ianni, M; Di Raimondo, F; Falzetti, F; Del Vecchio, L; Martelli, Massimo Fabrizio; Falini, Brunangelo
Current status and future perspectives in targeted therapy of NPM1-mutated AML
2022 Ranieri, Roberta; Pianigiani, Giulia; Sciabolacci, Sofia; Perriello, Vincenzo Maria; Marra, Andrea; Cardinali, Valeria; Pierangeli, Sara; Milano, Francesca; Gionfriddo, Ilaria; Brunetti, Lorenzo; Martelli, Maria Paola; Falini, Brunangelo
Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia
2015 Falini, Brunangelo; Brunetti, Lorenzo; Martelli, Maria Paola
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML
2021 Gionfriddo, Ilaria; Brunetti, Lorenzo; Mezzasoma, Federica; Milano, Francesca; Cardinali, Valeria; Ranieri, Roberta; Venanzi, Alessandra; Pierangeli, Sara; Vetro, Calogero; Spinozzi, Giulio; Dorillo, Erica; Wu, Hsin Chieh; Berthier, Caroline; Ciurnelli, Raffaella; Griffin, Melanie J; Jennings, Claire E; Tiacci, Enrico; Sportoletti, Paolo; Falzetti, Franca; de Thé, Hugues; Veal, Gareth J; Martelli, Maria Paola; Falini, Brunangelo
Dissecting the Hierarchical Level of Hematopoietic Progenitors' Involvement in AML with NPM1 Gene Mutation and Their Engraftment Potential in Immunocompromised Mice.
2009 Martelli, Maria Paola; Pettirossi, V; Thiede, C; Bonifacio, E; Di Ianni, M; Gionfriddo, I; Cecchini, D; Pacini, R; Tabarrini, A; Mezzasoma, F; Rossi, R; Giunchi, L; Oelschlagel, U; Brunetti, L; Gemei, M; Ciurnelli, R; Cecchetti, F; De Carolis, L; Liso, A; Di Raimondo, F; Martelli, Mf; Falini, B.
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
2017 Huang, Y. -H.; Su, J.; Lei, Y.; Brunetti, L.; Gundry, M. C.; Zhang, X.; Jeong, M.; Li, W.; Goodell, M. A.
DNMT3A in Leukemia
2017 Brunetti, Lorenzo; Gundry, Michael C.; Goodell, Margaret A.
Effect of the COVID-19 Pandemic on Laboratory and Clinical Research: A Testimony and a Call to Action From Researchers
2020 Kabanova, Anna; Gavriilaki, Eleni; Pelzer, Benedikt W; Brunetti, Lorenzo; Maiques-Diaz, Alba
Highly efficient gene disruption of murine and human hematopoietic progenitor cells by CRISPR/Cas9
2018 Brunetti, L.; Gundry, M. C.; Kitano, A.; Nakada, D.; Goodell, M. A.
Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9
2016 Gundry, Michael C.; Brunetti, Lorenzo; Lin, Angelique; Mayle, Allison E.; Kitano, Ayumi; Wagner, Dimitrios; Hsu, Joanne I.; Hoegenauer, Kevin A.; Rooney, Cliona M.; Goodell, Margaret A.; Nakada, Daisuke
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A venetoclax and azacitidine bridge-to-transplant strategy for NPM1-mutated acute myeloid leukaemia in molecular failure | 2023 | Sartor, C; Brunetti, L; Audisio, E; Cignetti, A; Zannoni, L; Cristiano, G; Nanni, J; Ciruolo, R; Zingarelli, F; Ottaviani, E; Patuelli, A; Bandini, L; Forte, D; Sciabolacci, S; Cardinali, V; Papayannidis, C; Cavo, M; Martelli, M P; Curti, A | |
| Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss | 2019 | Colleluori, G.; Aguirre, L.; Phadnis, U.; Fowler, K.; Armamento-Villareal, R.; Sun, Z.; Brunetti, L.; Hyoung Park, J.; Kaipparettu, B. A.; Putluri, N.; Auetumrongsawat, V.; Yarasheski, K.; Qualls, C.; Villareal, D. T. | |
| Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells | 2015 | Martelli, Maria Paola; Gionfriddo, Ilaria; Mezzasoma, Federica; Milano, Francesca; Pierangeli, Sara; Mulas, Floriana; Pacini, Roberta; Tabarrini, Alessia; Pettirossi, Valentina; Rossi, Roberta; Vetro, Calogero; Brunetti, Lorenzo; Sportoletti, Paolo; Tiacci, Enrico; Di Raimondo, Francesco; Falini, Brunangelo | |
| ARSENIC TRIOXIDE AND ALL-TRANS-RETINOIC ACID TARGET NPM1 MUTANT ONCOPROTEIN LEVELS AND INDUCE APOPTOSIS IN NPM1-MUTATED AML CELLS | 2015 | Martelli, Maria Paola; Gionfriddo, Ilaria; Mezzasoma, Federica; Milano, Francesca; Pierangeli, Sara; Pettirossi, Valentina; Rossi, R.; Strozzini, Francesca; Vetro, C.; Brunetti, L.; Sportoletti, Paolo; Tiacci, Enrico; Di Raimondo, F.; Falini, Brunangelo | |
| Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice | 2020 | Sportoletti, Paolo; Sorcini, Daniele; Guzman, Anna G; Reyes, Jaime M; Stella, Arianna; Marra, Andrea; Sartori, Sara; Brunetti, Lorenzo; Rossi, Roberta; Papa, Beatrice Del; Adamo, Francesco Maria; Pianigiani, Giulia; Betti, Camilla; Scialdone, Annarita; Guarente, Valerio; Spinozzi, Giulio; Tini, Valentina; Martelli, Maria Paola; Goodell, Margaret A; Falini, Brunangelo | |
| Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin | 2017 | Brunetti, L; Di Battista, V; Venanzi, A; Schiavoni, G; Martelli, M. P.; Ascani, S; Mecucci, C; Tiacci, E; Falini, B | |
| CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression | 2020 | Fousek, Kristen; Watanabe, Junji; Joseph, Sujith K; George, Ann; An, Xingyue; Byrd, Tiara T; Morris, Jessica S; Luong, Annie; Martínez-Paniagua, Melisa A; Sanber, Khaled; Navai, Shoba A; Gad, Ahmed Z; Salsman, Vita S; Mathew, Pretty R; Kim, Hye Na; Wagner, Dimitrios L; Brunetti, Lorenzo; Jang, Albert; Baker, Matthew L; Varadarajan, Navin; Hegde, Meenakshi; Kim, Yong-Mi; Heisterkamp, Nora; Abdel-Azim, Hisham; Ahmed, Nabil | |
| CD123 (IL-3R alpha) IS CONSISTENTLY EXPRESSED ON ACUTE MYELOID LEUKEMIA (AML) CARRYING NUCLEOPHOSMIN (NPM1) GENE MUTATION | 2014 | Brunetti, Lorenzo; Gionfriddo, Ilaria; Rossi, Roberta; Mezzasoma, Federica; Milano, Francesca; Vetro, C.; Di Raimondo, F.; Falini, Brunangelo; Martelli, Maria Paola | |
| CD123 Is Consistently Expressed on NPM1-Mutated AML Cells | 2021 | Perriello, V. M.; Gionfriddo, I.; Rossi, R.; Milano, F.; Mezzasoma, F.; Marra, A.; Spinelli, O.; Rambaldi, A.; Annibali, O.; Avvisati, G.; Di Raimondo, F.; Ascani, S.; Falini, B.; Martelli, M. P.; Brunetti, L. | |
| CD200/OX2, a cell surface molecule with immuno-regulatory function, is consistently expressed on hairy cell leukaemia neoplastic cells: Correspondence | 2009 | Brunetti, L.; Di Noto, R.; Abate, G.; Gorrese, M.; Gravetti, A.; Raia, M.; Scalia, G.; Pascariello, C.; Camera, A.; Del Vecchio, L. | |
| CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice. | 2010 | Martelli, Maria Paola; Pettirossi, Valentina; Thiede, C; Bonifacio, E; Mezzasoma, F; Cecchini, D; Pacini, R; Tabarrini, A; Ciurnelli, R; Gionfriddo, I; Manes, N; Rossi, R; Giunchi, L; Oelschlägel, U; Brunetti, L; Gemei, M; Delia, M; Specchia, G; Liso, A; Di Ianni, M; Di Raimondo, F; Falzetti, F; Del Vecchio, L; Martelli, Massimo Fabrizio; Falini, Brunangelo | |
| Current status and future perspectives in targeted therapy of NPM1-mutated AML | 2022 | Ranieri, Roberta; Pianigiani, Giulia; Sciabolacci, Sofia; Perriello, Vincenzo Maria; Marra, Andrea; Cardinali, Valeria; Pierangeli, Sara; Milano, Francesca; Gionfriddo, Ilaria; Brunetti, Lorenzo; Martelli, Maria Paola; Falini, Brunangelo | |
| Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia | 2015 | Falini, Brunangelo; Brunetti, Lorenzo; Martelli, Maria Paola | |
| Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML | 2021 | Gionfriddo, Ilaria; Brunetti, Lorenzo; Mezzasoma, Federica; Milano, Francesca; Cardinali, Valeria; Ranieri, Roberta; Venanzi, Alessandra; Pierangeli, Sara; Vetro, Calogero; Spinozzi, Giulio; Dorillo, Erica; Wu, Hsin Chieh; Berthier, Caroline; Ciurnelli, Raffaella; Griffin, Melanie J; Jennings, Claire E; Tiacci, Enrico; Sportoletti, Paolo; Falzetti, Franca; de Thé, Hugues; Veal, Gareth J; Martelli, Maria Paola; Falini, Brunangelo | |
| Dissecting the Hierarchical Level of Hematopoietic Progenitors' Involvement in AML with NPM1 Gene Mutation and Their Engraftment Potential in Immunocompromised Mice. | 2009 | Martelli, Maria Paola; Pettirossi, V; Thiede, C; Bonifacio, E; Di Ianni, M; Gionfriddo, I; Cecchini, D; Pacini, R; Tabarrini, A; Mezzasoma, F; Rossi, R; Giunchi, L; Oelschlagel, U; Brunetti, L; Gemei, M; Ciurnelli, R; Cecchetti, F; De Carolis, L; Liso, A; Di Raimondo, F; Martelli, Mf; Falini, B. | |
| DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A | 2017 | Huang, Y. -H.; Su, J.; Lei, Y.; Brunetti, L.; Gundry, M. C.; Zhang, X.; Jeong, M.; Li, W.; Goodell, M. A. | |
| DNMT3A in Leukemia | 2017 | Brunetti, Lorenzo; Gundry, Michael C.; Goodell, Margaret A. | |
| Effect of the COVID-19 Pandemic on Laboratory and Clinical Research: A Testimony and a Call to Action From Researchers | 2020 | Kabanova, Anna; Gavriilaki, Eleni; Pelzer, Benedikt W; Brunetti, Lorenzo; Maiques-Diaz, Alba | |
| Highly efficient gene disruption of murine and human hematopoietic progenitor cells by CRISPR/Cas9 | 2018 | Brunetti, L.; Gundry, M. C.; Kitano, A.; Nakada, D.; Goodell, M. A. | |
| Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9 | 2016 | Gundry, Michael C.; Brunetti, Lorenzo; Lin, Angelique; Mayle, Allison E.; Kitano, Ayumi; Wagner, Dimitrios; Hsu, Joanne I.; Hoegenauer, Kevin A.; Rooney, Cliona M.; Goodell, Margaret A.; Nakada, Daisuke |