SIRAGUSA, LYDIA
SIRAGUSA, LYDIA
DIPARTIMENTO DI CHIMICA (attivo dal 01/11/1982 al 31/12/2013)
An Integrated Machine Learning Model To Spot Peptide Binding Pockets in 3D Protein Screening
2022 Trisciuzzi, Daniela; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Nicolotti, Orazio
Automatic Identification of Lansoprazole Degradants under Stress Conditions by LC-HRMS with MassChemSite and WebChembase
2021 Bonciarelli, S.; Desantis, J.; Goracci, L.; Siragusa, L.; Zamora, I.; Ortega-Carrasco, E.
BioGPS descriptors for rational engineering of enzyme promiscuity and structure based bioinformatic analysis
2014 Ferrario, Valerio; Siragusa, Lydia; Ebert, Cynthia; Baroni, Massimo; Foscato, Marco; Cruciani, Gabriele; Gardossi, Lucia
BioGPS: Navigating biological space to predict polypharmacology, off-targeting, and selectivity
2015 Siragusa, Lydia; Cross, Simon; Baroni, Massimo; Goracci, Laura; Cruciani, Gabriele
Bisphenol A binding promiscuity: A virtual journey through the universe of proteins
2020 Lo Piparo, Elena; Siragusa, Lydia; Raymond, Frederic; Passeri, Giovanna Ilaria; Cruciani, Gabriele; Schilter, Benoît
Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case
2016 Siragusa, Lydia; Luciani, Rosaria; Borsari, Chiara; Ferrari, Stefania; Costi, Maria Paola; Cruciani, Gabriele; Spyrakis, Francesca
Detecting similar binding pockets to enable systems polypharmacology
2017 Duran-frigola, Miguel; Siragusa, Lydia; Ruppin, Eytan; Barril, Xavier; Cruciani, Gabriele; Aloy, Patrick
Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A
2022 Pacifico, R.; Del Gaudio, N.; Bove, G.; Altucci, L.; Siragusa, L.; Cruciani, G.; Ruvo, M.; Bellavita, R.; Grieco, P.; Adamo, M. F. A.
ELIOT: A platform to navigate the E3 pocketome and aid the design of new PROTACs
2023 Palomba, Tommaso; Baroni, Massimo; Cross, Simon; Cruciani, Gabriele; Siragusa, Lydia
Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design
2022 Palomba, Tommaso; Tassone, Giusy; Vacca, Carmine; Bartalucci, Matteo; Valeri, Aurora; Pozzi, Cecilia; Cross, Simon; Siragusa, Lydia; Desantis, Jenny
Exploring Ligand Binding Domain Dynamics in the NRs Superfamily
2022 D'Arrigo, Giulia; Autiero, Ida; Gianquinto, Eleonora; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Spyrakis, Francesca
Indomethacin-based PROTACs as pan-coronavirus antiviral agents
2021 Desantis, J.; Mercorelli, B.; Celegato, M.; Croci, F.; Bazzacco, A.; Baroni, M.; Siragusa, L.; Cruciani, G.; Loregian, A.; Goracci, L.
Targeting Nsp9 as an anti-SARS-CoV-2 strategy
2021 Farias, A. B.; Candiotto, G.; Siragusa, L.; Goracci, L.; Cruciani, G.; Oliveira, E. R. A.; Horta, B. A. C.
Targeting protein-protein interactions with low molecular weight and short peptide modulators: insights on disease pathways and starting points for drug discovery
2023 Trisciuzzi, Daniela; Villoutreix, Bruno O; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Nicolotti, Orazio
Vitamin E: metabolism and molecular aspects
2020 Torquato, Pierangelo; Marinelli, Rita; Bartolini, Desirée; Giusepponi, Danilo; Cruciani, Gabriele; Siragusa, Lydia; Galarini, Roberta; Sebastiani, Bartolomeo; Gioiello, Antimo; Galli, Francesco
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| An Integrated Machine Learning Model To Spot Peptide Binding Pockets in 3D Protein Screening | 2022 | Trisciuzzi, Daniela; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Nicolotti, Orazio | |
| Automatic Identification of Lansoprazole Degradants under Stress Conditions by LC-HRMS with MassChemSite and WebChembase | 2021 | Bonciarelli, S.; Desantis, J.; Goracci, L.; Siragusa, L.; Zamora, I.; Ortega-Carrasco, E. | |
| BioGPS descriptors for rational engineering of enzyme promiscuity and structure based bioinformatic analysis | 2014 | Ferrario, Valerio; Siragusa, Lydia; Ebert, Cynthia; Baroni, Massimo; Foscato, Marco; Cruciani, Gabriele; Gardossi, Lucia | |
| BioGPS: Navigating biological space to predict polypharmacology, off-targeting, and selectivity | 2015 | Siragusa, Lydia; Cross, Simon; Baroni, Massimo; Goracci, Laura; Cruciani, Gabriele | |
| Bisphenol A binding promiscuity: A virtual journey through the universe of proteins | 2020 | Lo Piparo, Elena; Siragusa, Lydia; Raymond, Frederic; Passeri, Giovanna Ilaria; Cruciani, Gabriele; Schilter, Benoît | |
| Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case | 2016 | Siragusa, Lydia; Luciani, Rosaria; Borsari, Chiara; Ferrari, Stefania; Costi, Maria Paola; Cruciani, Gabriele; Spyrakis, Francesca | |
| Detecting similar binding pockets to enable systems polypharmacology | 2017 | Duran-frigola, Miguel; Siragusa, Lydia; Ruppin, Eytan; Barril, Xavier; Cruciani, Gabriele; Aloy, Patrick | |
| Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A | 2022 | Pacifico, R.; Del Gaudio, N.; Bove, G.; Altucci, L.; Siragusa, L.; Cruciani, G.; Ruvo, M.; Bellavita, R.; Grieco, P.; Adamo, M. F. A. | |
| ELIOT: A platform to navigate the E3 pocketome and aid the design of new PROTACs | 2023 | Palomba, Tommaso; Baroni, Massimo; Cross, Simon; Cruciani, Gabriele; Siragusa, Lydia | |
| Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design | 2022 | Palomba, Tommaso; Tassone, Giusy; Vacca, Carmine; Bartalucci, Matteo; Valeri, Aurora; Pozzi, Cecilia; Cross, Simon; Siragusa, Lydia; Desantis, Jenny | |
| Exploring Ligand Binding Domain Dynamics in the NRs Superfamily | 2022 | D'Arrigo, Giulia; Autiero, Ida; Gianquinto, Eleonora; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Spyrakis, Francesca | |
| Indomethacin-based PROTACs as pan-coronavirus antiviral agents | 2021 | Desantis, J.; Mercorelli, B.; Celegato, M.; Croci, F.; Bazzacco, A.; Baroni, M.; Siragusa, L.; Cruciani, G.; Loregian, A.; Goracci, L. | |
| Targeting Nsp9 as an anti-SARS-CoV-2 strategy | 2021 | Farias, A. B.; Candiotto, G.; Siragusa, L.; Goracci, L.; Cruciani, G.; Oliveira, E. R. A.; Horta, B. A. C. | |
| Targeting protein-protein interactions with low molecular weight and short peptide modulators: insights on disease pathways and starting points for drug discovery | 2023 | Trisciuzzi, Daniela; Villoutreix, Bruno O; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Nicolotti, Orazio | |
| Vitamin E: metabolism and molecular aspects | 2020 | Torquato, Pierangelo; Marinelli, Rita; Bartolini, Desirée; Giusepponi, Danilo; Cruciani, Gabriele; Siragusa, Lydia; Galarini, Roberta; Sebastiani, Bartolomeo; Gioiello, Antimo; Galli, Francesco |