NIZI, MARIA GIULIA
NIZI, MARIA GIULIA
Dipartimento di Scienze Farmaceutiche
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors
2021 Pismataro, M. C.; Felicetti, T.; Bertagnin, C.; Nizi, M. G.; Bonomini, A.; Barreca, M. L.; Cecchetti, V.; Jochmans, D.; De Jonghe, S.; Neyts, J.; Loregian, A.; Tabarrini, O.; Massari, S.
[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes
2023 Murthy, Sudarshan; Nizi, Maria Giulia; Maksimainen, Mirko M; Massari, Serena; Alaviuhkola, Juho; Lippok, Barbara E; Vagaggini, Chiara; Sowa, Sven T; Galera-Prat, Albert; Ashok, Yashwanth; Venkannagari, Harikanth; Prunskaite-Hyyryläinen, Renata; Dreassi, Elena; Lüscher, Bernhard; Korn, Patricia; Tabarrini, Oriana; Lehtiö, Lari
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors
2020 Nizi, M. G.; Desantis, J.; Nakatani, Y.; Massari, S.; Mazzarella, M. A.; Shetye, G.; Sabatini, S.; Barreca, M. L.; Manfroni, G.; Felicetti, T.; Rushton-Green, R.; Hards, K.; Latacz, G.; Satala, G.; Bojarski, A. J.; Cecchetti, V.; Kolar, M. H.; Handzlik, J.; Cook, G. M.; Franzblau, S. G.; Tabarrini, O.
Compounds for use in the treatment of cancer and inflammatory conditions
2023 Lehtiö, L; Maksimainen, M; Murthy Sudarshan, N; Tabarrini, O; Nizi, M. G.; Massari, S
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity
2022 Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana
Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions
2021 Massari, S.; Desantis, J.; Nizi, M. G.; Cecchetti, V.; Tabarrini, O.
Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules
2022 Nizi, Maria Giulia; Maksimainen, Mirko M; Lehtiö, Lari; Tabarrini, Oriana
Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15
2022 Nizi, Maria Giulia; Maksimainen, Mirko M; Murthy, Sudarshan; Massari, Serena; Alaviuhkola, Juhob; Lippok, Barbara E.; Sowa, Sven T.; Galera-Prat, Albertb; Prunskaite-Hyyryläinen, Renata; Lüscher, Bernhard; Korn, Patricia; Lehtiö, Lari; Tabarrini, Oriana
Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs
2023 Nizi, M. G.; Sarnari, C.; Tabarrini, O.
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position
2018 Felicetti, T.; Cannalire, R.; Nizi, M. G.; Tabarrini, O.; Massari, S.; Barreca, M. L.; Manfroni, G.; Schindler, B. D.; Cecchetti, V.; Kaatz, G. W.; Sabatini, S.
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase.
2021 Massari, S.; Bertagnin, C.; Pismataro, M. C.; Donnadio, A.; Nannetti, G.; Felicetti, T.; Di Bona, S.; Nizi, M. G.; Tensi, L.; Manfroni, G.; Loza, M. I.; Sabatini, S.; Cecchetti, V.; Brea, J.; Goracci, L.; Loregian, A.; Tabarrini, O.
Synthetically accessible de novo design using reaction vectors: Application to PARP1 inhibitors**
2024 Ghiandoni, Gian Marco; Flanagan, Stuart R.; Bodkin, Michael J.; Nizi, Maria Giulia; Galera‐prat, Albert; Brai, Annalaura; Chen, Beining; Wallace, James E. A.; Hristozov, Dimitar; Webster, James; Manfroni, Giuseppe; Lehtiö, Lari; Tabarrini, Oriana; Gillet, Valerie J.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors | 2021 | Pismataro, M. C.; Felicetti, T.; Bertagnin, C.; Nizi, M. G.; Bonomini, A.; Barreca, M. L.; Cecchetti, V.; Jochmans, D.; De Jonghe, S.; Neyts, J.; Loregian, A.; Tabarrini, O.; Massari, S. | |
| [1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes | 2023 | Murthy, Sudarshan; Nizi, Maria Giulia; Maksimainen, Mirko M; Massari, Serena; Alaviuhkola, Juho; Lippok, Barbara E; Vagaggini, Chiara; Sowa, Sven T; Galera-Prat, Albert; Ashok, Yashwanth; Venkannagari, Harikanth; Prunskaite-Hyyryläinen, Renata; Dreassi, Elena; Lüscher, Bernhard; Korn, Patricia; Tabarrini, Oriana; Lehtiö, Lari | |
| Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors | 2020 | Nizi, M. G.; Desantis, J.; Nakatani, Y.; Massari, S.; Mazzarella, M. A.; Shetye, G.; Sabatini, S.; Barreca, M. L.; Manfroni, G.; Felicetti, T.; Rushton-Green, R.; Hards, K.; Latacz, G.; Satala, G.; Bojarski, A. J.; Cecchetti, V.; Kolar, M. H.; Handzlik, J.; Cook, G. M.; Franzblau, S. G.; Tabarrini, O. | |
| Compounds for use in the treatment of cancer and inflammatory conditions | 2023 | Lehtiö, L; Maksimainen, M; Murthy Sudarshan, N; Tabarrini, O; Nizi, M. G.; Massari, S | |
| Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity | 2022 | Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana | |
| Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions | 2021 | Massari, S.; Desantis, J.; Nizi, M. G.; Cecchetti, V.; Tabarrini, O. | |
| Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules | 2022 | Nizi, Maria Giulia; Maksimainen, Mirko M; Lehtiö, Lari; Tabarrini, Oriana | |
| Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15 | 2022 | Nizi, Maria Giulia; Maksimainen, Mirko M; Murthy, Sudarshan; Massari, Serena; Alaviuhkola, Juhob; Lippok, Barbara E.; Sowa, Sven T.; Galera-Prat, Albertb; Prunskaite-Hyyryläinen, Renata; Lüscher, Bernhard; Korn, Patricia; Lehtiö, Lari; Tabarrini, Oriana | |
| Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs | 2023 | Nizi, M. G.; Sarnari, C.; Tabarrini, O. | |
| Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position | 2018 | Felicetti, T.; Cannalire, R.; Nizi, M. G.; Tabarrini, O.; Massari, S.; Barreca, M. L.; Manfroni, G.; Schindler, B. D.; Cecchetti, V.; Kaatz, G. W.; Sabatini, S. | |
| Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. | 2021 | Massari, S.; Bertagnin, C.; Pismataro, M. C.; Donnadio, A.; Nannetti, G.; Felicetti, T.; Di Bona, S.; Nizi, M. G.; Tensi, L.; Manfroni, G.; Loza, M. I.; Sabatini, S.; Cecchetti, V.; Brea, J.; Goracci, L.; Loregian, A.; Tabarrini, O. | |
| Synthetically accessible de novo design using reaction vectors: Application to PARP1 inhibitors** | 2024 | Ghiandoni, Gian Marco; Flanagan, Stuart R.; Bodkin, Michael J.; Nizi, Maria Giulia; Galera‐prat, Albert; Brai, Annalaura; Chen, Beining; Wallace, James E. A.; Hristozov, Dimitar; Webster, James; Manfroni, Giuseppe; Lehtiö, Lari; Tabarrini, Oriana; Gillet, Valerie J. |