Sfoglia per Autore
Molecular determinats for metabotropic glutamate receptor activation and blockade. Molecular dynamics and electrostatic potential analysis studies
2002 Costantino, Gabriele; M., Belenekin; Macchiarulo, Antonio; Camaioni, Emidio; Pellicciari, Roberto
Studies guanosine binding sites in rat brain: S.A.R. analysis and pharmacophore design
2002 Bombi, G.; Morelli, A.; Palmieri, C.; Costantino, Gabriele; Pellicciari, Roberto; Camaioni, Emidio; Traversa, U.
Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids
2002 Marinozzi, Maura; Camaioni, Emidio; Costantino, Gabriele; G., Giorgi; Macchiarulo, Antonio; Pellicciari, Roberto
1,4 Benzothiazine and 1,4 benzoxazine imidazole derivatives with antifungal activity: a docking study
2002 Macchiarulo, Antonio; Costantino, Gabriele; Fringuelli, D.; Vecchiarelli, Anna; Schiaffella, Fausto; Fringuelli, Renata
Molecular dynamics simulation of the ligand binding domain of mGluR1 in response to agonist and antagonist binding.
2002 Costantino, Gabriele; Macchiarulo, Antonio; Belenikin, M.; Pellicciari, R.
Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids
2002 Pellicciari, Roberto; Marinozzi, Maura; Camaioni, Emidio; Costantino, Gabriele; Nunez, M.; Gasparini, F.; Giorgi, G.; Macchiarulo, Antonio; Subramanian, N.
PARP-1 and its inhibitors: molecular modeling studies
2003 Pellicciari, Roberto; Camaioni, Emidio; Macchiarulo, Antonio; Costantino, Gabriele
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents
2003 Camaioni, Emidio; Costantino, Gabriele; Macchiarulo, Antonio; Marinozzi, Maura; F., Moroni; Pellicciari, Roberto
Binding modes of noncompetitive AMPA Antagonists: A computational approach
2003 De Luca, L.; Macchiarulo, Antonio; Costantino, Gabriele; Barreca, MARIA LETIZIA; Gitto, R.; Chimirri, A.; Pellicciari, Roberto
Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase.
2003 Pellicciari, Roberto; Amori, Laura; Costantino, Gabriele; Giordani, A.; Macchiarulo, Antonio; Mattoli, L.; Pevarello, P.; Speciale, C.; Varasi, M.
Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction
2003 Camaioni, Emidio; Traversa, U.; Costantino, Gabriele; Macchiarulo, Antonio; Bombi, G.; Caciagli, F.; Palmieri, C.; Pellicciari, Roberto
Rat brain guanosine binding site. Biological studies and pseudo-Receptor construction
2003 Traversa, U.; Bombi, G.; Camaioni, Emidio; Macchiarulo, Antonio; Costantino, Gabriele; Palmieri, C.; Caciagli, F.; Pellicciari, Roberto
Novel Isoquinoline-Derived Inhibitors of Poly(ADP-Ribose) Polymerase-1: Pharmacological Characterization and Neuroprotective Effects in an in Vitro Model of Cerebral Ischemia
2003 Chiarugi, A; Meli, E; Calvani, M; Picca, R; Baronti, R; Camaioni, Emidio; Costantino, Gabriele; Marinozzi, Maura; Pellegrini Giampietro, De; Pellicciari, Roberto; Moroni, F.
Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor.
2003 Pellicciari, Roberto; Camaioni, Emidio; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Moroni, F.; Natalini, Benedetto
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR)
2003 Costantino, Gabriele; Macchiarulo, Antonio; Entrena Guadix, A.; Camaioni, Emidio; Pellicciari, Roberto
Stereoselective Synthesis and Preliminary Evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): Identification of (+)-3-MATIDA as a Novel mGluR1 Competitive Antagonist
2004 Costantino, Gabriele; Marinozzi, Maura; Camaioni, Emidio; Natalini, Benedetto; Sarichelou, I.; Micheli, F.; Cavanni, P.; Faedo, S.; Noe, C.; Moroni, F.; Pellicciari, Roberto
Studies on the interaction between PARP’s catalytic site and inhibitors. Design and synthesis of new class of inhibitor derivatives
2004 Camaioni, Emidio; A., Leone; Costantino, Gabriele; D., Bellocchi; Macchiarulo, Antonio; Pellicciari, Roberto
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses
2004 Macchiarulo, Antonio; Costantino, Gabriele; Meniconi, Mirco; Pleban, K.; Ecker, G.; Bellocchi, Daniele; Pellicciari, Roberto
Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure Activity Relationship of a Series of Body and Side Chain Modified Analogs of Chenodeoxycholic Acid
2004 Pellicciari, Roberto; Costantino, Gabriele; Camaioni, Emidio; Sadeghpour, B. M.; Entrena Guadix, A.; Willson, T.; Fiorucci, Stefano; Clerici, C.; Gioiello, Antimo
Homology Model of the Multidrag transporter LmrA from Lactococcus Lactis
2004 Pleban, K.; Macchiarulo, Antonio; Costantino, Gabriele; Pellicciari, Roberto; Chiba, P.; Ecker, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Molecular determinats for metabotropic glutamate receptor activation and blockade. Molecular dynamics and electrostatic potential analysis studies | 2002 | Costantino, Gabriele; M., Belenekin; Macchiarulo, Antonio; Camaioni, Emidio; Pellicciari, Roberto | |
| Studies guanosine binding sites in rat brain: S.A.R. analysis and pharmacophore design | 2002 | Bombi, G.; Morelli, A.; Palmieri, C.; Costantino, Gabriele; Pellicciari, Roberto; Camaioni, Emidio; Traversa, U. | |
| Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids | 2002 | Marinozzi, Maura; Camaioni, Emidio; Costantino, Gabriele; G., Giorgi; Macchiarulo, Antonio; Pellicciari, Roberto | |
| 1,4 Benzothiazine and 1,4 benzoxazine imidazole derivatives with antifungal activity: a docking study | 2002 | Macchiarulo, Antonio; Costantino, Gabriele; Fringuelli, D.; Vecchiarelli, Anna; Schiaffella, Fausto; Fringuelli, Renata | |
| Molecular dynamics simulation of the ligand binding domain of mGluR1 in response to agonist and antagonist binding. | 2002 | Costantino, Gabriele; Macchiarulo, Antonio; Belenikin, M.; Pellicciari, R. | |
| Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids | 2002 | Pellicciari, Roberto; Marinozzi, Maura; Camaioni, Emidio; Costantino, Gabriele; Nunez, M.; Gasparini, F.; Giorgi, G.; Macchiarulo, Antonio; Subramanian, N. | |
| PARP-1 and its inhibitors: molecular modeling studies | 2003 | Pellicciari, Roberto; Camaioni, Emidio; Macchiarulo, Antonio; Costantino, Gabriele | |
| Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents | 2003 | Camaioni, Emidio; Costantino, Gabriele; Macchiarulo, Antonio; Marinozzi, Maura; F., Moroni; Pellicciari, Roberto | |
| Binding modes of noncompetitive AMPA Antagonists: A computational approach | 2003 | De Luca, L.; Macchiarulo, Antonio; Costantino, Gabriele; Barreca, MARIA LETIZIA; Gitto, R.; Chimirri, A.; Pellicciari, Roberto | |
| Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase. | 2003 | Pellicciari, Roberto; Amori, Laura; Costantino, Gabriele; Giordani, A.; Macchiarulo, Antonio; Mattoli, L.; Pevarello, P.; Speciale, C.; Varasi, M. | |
| Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction | 2003 | Camaioni, Emidio; Traversa, U.; Costantino, Gabriele; Macchiarulo, Antonio; Bombi, G.; Caciagli, F.; Palmieri, C.; Pellicciari, Roberto | |
| Rat brain guanosine binding site. Biological studies and pseudo-Receptor construction | 2003 | Traversa, U.; Bombi, G.; Camaioni, Emidio; Macchiarulo, Antonio; Costantino, Gabriele; Palmieri, C.; Caciagli, F.; Pellicciari, Roberto | |
| Novel Isoquinoline-Derived Inhibitors of Poly(ADP-Ribose) Polymerase-1: Pharmacological Characterization and Neuroprotective Effects in an in Vitro Model of Cerebral Ischemia | 2003 | Chiarugi, A; Meli, E; Calvani, M; Picca, R; Baronti, R; Camaioni, Emidio; Costantino, Gabriele; Marinozzi, Maura; Pellegrini Giampietro, De; Pellicciari, Roberto; Moroni, F. | |
| Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor. | 2003 | Pellicciari, Roberto; Camaioni, Emidio; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Moroni, F.; Natalini, Benedetto | |
| Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) | 2003 | Costantino, Gabriele; Macchiarulo, Antonio; Entrena Guadix, A.; Camaioni, Emidio; Pellicciari, Roberto | |
| Stereoselective Synthesis and Preliminary Evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): Identification of (+)-3-MATIDA as a Novel mGluR1 Competitive Antagonist | 2004 | Costantino, Gabriele; Marinozzi, Maura; Camaioni, Emidio; Natalini, Benedetto; Sarichelou, I.; Micheli, F.; Cavanni, P.; Faedo, S.; Noe, C.; Moroni, F.; Pellicciari, Roberto | |
| Studies on the interaction between PARP’s catalytic site and inhibitors. Design and synthesis of new class of inhibitor derivatives | 2004 | Camaioni, Emidio; A., Leone; Costantino, Gabriele; D., Bellocchi; Macchiarulo, Antonio; Pellicciari, Roberto | |
| Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses | 2004 | Macchiarulo, Antonio; Costantino, Gabriele; Meniconi, Mirco; Pleban, K.; Ecker, G.; Bellocchi, Daniele; Pellicciari, Roberto | |
| Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure Activity Relationship of a Series of Body and Side Chain Modified Analogs of Chenodeoxycholic Acid | 2004 | Pellicciari, Roberto; Costantino, Gabriele; Camaioni, Emidio; Sadeghpour, B. M.; Entrena Guadix, A.; Willson, T.; Fiorucci, Stefano; Clerici, C.; Gioiello, Antimo | |
| Homology Model of the Multidrag transporter LmrA from Lactococcus Lactis | 2004 | Pleban, K.; Macchiarulo, Antonio; Costantino, Gabriele; Pellicciari, Roberto; Chiba, P.; Ecker, G. |
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