Sfoglia per Autore
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity
2015 Sancineto, Luca; Mariotti, Alice; Bagnoli, Luana; Marini, Francesca; Desantis, Jenny; Iraci, Nunzio; Santi, Claudio; Pannecouque, Christophe; Tabarrini, Oriana
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction
2015 Massari, Serena; Nannetti, Giulio; Desantis, Jenny; Muratore, Giulia; Sabatini, Stefano; Manfroni, Giuseppe; Mercorelli, Beatrice; Cecchetti, Violetta; Palù, Giorgio; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura; Tabarrini, Oriana
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors
2016 Corona, Angela; Desantis, Jenny; Massari, Serena; Distinto, Simona; Masaoka, Takashi; Sabatini, Stefano; Esposito, Francesca; Manfroni, Giuseppe; Maccioni, Elias; Cecchetti, Violetta; Pannecouque, Christophe; Le Grice, Stuart F. J.; Tramontano, Enzo; Tabarrini, Oriana
Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Protein-protein Interaction as a Target for Next-generation Anti-influenza Therapeutics.
2016 Massari, Serena; Goracci, Laura; Desantis, Jenny; Tabarrini, Oriana
Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV
2016 Tabarrini, Oriana; Desantis, Jenny; Massari, Serena
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives
2017 Massari, Serena; Desantis, Jenny; Nannetti, Giulio; Sabatini, Stefano; Tortorella, Sara; Goracci, Laura; Cecchetti, Violetta; Loregian, Arianna; Tabarrini, Oriana
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity
2017 Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Letizia Barreca, Maria; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana
2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors
2018 Nkizinkiko, Yves; Desantis, Jenny; Koivunen, Jarkko; Teemu, Haikarainen; Murthy, Sudarshan; Sancineto, Luca; Massari, Serena; Ianni, Federica; Obaji, Ezeogo; Loza Maria, I; Pihlajaniemi, Taina; Brea, Jose; Tabarrini, Oriana; Lehtiö, Lari
Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.
2018 Matthes, F; Massari, S; Bochicchio, A; Schorpp, K; Schilling, J; Weber, S; Offermann, N; Desantis, J; Wanker, E; Carloni, P; Hadian, K; Tabarrini, O; Rossetti, G; Krauss, S
4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10
2018 Murthy, S; Desantis, J; Verheugd, P; Maksimainen, Mm; Venkannagari, H; Massari, S; Ashok, Y; Obaji, E; Nkizinkinko, Y; Lüscher, B; Tabarrini, O; Lehtiö, L
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors
2019 Massari, Serena; Corona, Angela; Distinto, Simona; Desantis, Jenny; Caredda, Alessia; Sabatini, Stefano; Manfroni, Giuseppe; Felicetti, Tommaso; Cecchetti, Violetta; Pannecouque, Christophe; Maccioni, Elias; Tramontano, Enzo; Tabarrini, Oriana
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance
2019 Nannetti, G.; Massari, S.; Mercorelli, B.; Bertagnin, C.; Desantis, J.; Palù, G.; Tabarrini, O.; Loregian, A.
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders.
2019 Desantis, J.; Massari, S.; Sosic, A.; Manfroni, G.; Cannalire, R.; Felicetti, T.; Pannecouque, P.; Gatto, B.; Tabarrini, O.
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity
2020 Desantis, J.; Massari, S.; Corona, A.; Astolfi, A.; Sabatini, S.; Manfroni, G.; Palazzotti, D.; Cecchetti, V.; Pannecouque, C.; Tramontano, E.; Tabarrini, O.
Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications
2020 Goracci, L.; Desantis, J.; Valeri, A.; Castellani, B.; Eleuteri, M.; Cruciani, G.
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors
2020 Nizi, M. G.; Desantis, J.; Nakatani, Y.; Massari, S.; Mazzarella, M. A.; Shetye, G.; Sabatini, S.; Barreca, M. L.; Manfroni, G.; Felicetti, T.; Rushton-Green, R.; Hards, K.; Latacz, G.; Satala, G.; Bojarski, A. J.; Cecchetti, V.; Kolar, M. H.; Handzlik, J.; Cook, G. M.; Franzblau, S. G.; Tabarrini, O.
Effects of MTX-23, a novel PROTAC of androgen receptor splice variant-7 and androgen receptor, on CRPC resistant to second-line antiandrogen therapy
2021 Lee, G. T.; Nagaya, N.; Desantis, J.; Madura, K.; Sabaawy, H. E.; Kim, W. -J.; Vaz, R. J.; Cruciani, G.; Kim, I. Y.
Indomethacin-based PROTACs as pan-coronavirus antiviral agents
2021 Desantis, J.; Mercorelli, B.; Celegato, M.; Croci, F.; Bazzacco, A.; Baroni, M.; Siragusa, L.; Cruciani, G.; Loregian, A.; Goracci, L.
Automatic Identification of Lansoprazole Degradants under Stress Conditions by LC-HRMS with MassChemSite and WebChembase
2021 Bonciarelli, S.; Desantis, J.; Goracci, L.; Siragusa, L.; Zamora, I.; Ortega-Carrasco, E.
Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions
2021 Massari, S.; Desantis, J.; Nizi, M. G.; Cecchetti, V.; Tabarrini, O.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity | 2015 | Sancineto, Luca; Mariotti, Alice; Bagnoli, Luana; Marini, Francesca; Desantis, Jenny; Iraci, Nunzio; Santi, Claudio; Pannecouque, Christophe; Tabarrini, Oriana | |
| A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction | 2015 | Massari, Serena; Nannetti, Giulio; Desantis, Jenny; Muratore, Giulia; Sabatini, Stefano; Manfroni, Giuseppe; Mercorelli, Beatrice; Cecchetti, Violetta; Palù, Giorgio; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura; Tabarrini, Oriana | |
| Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors | 2016 | Corona, Angela; Desantis, Jenny; Massari, Serena; Distinto, Simona; Masaoka, Takashi; Sabatini, Stefano; Esposito, Francesca; Manfroni, Giuseppe; Maccioni, Elias; Cecchetti, Violetta; Pannecouque, Christophe; Le Grice, Stuart F. J.; Tramontano, Enzo; Tabarrini, Oriana | |
| Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Protein-protein Interaction as a Target for Next-generation Anti-influenza Therapeutics. | 2016 | Massari, Serena; Goracci, Laura; Desantis, Jenny; Tabarrini, Oriana | |
| Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV | 2016 | Tabarrini, Oriana; Desantis, Jenny; Massari, Serena | |
| Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives | 2017 | Massari, Serena; Desantis, Jenny; Nannetti, Giulio; Sabatini, Stefano; Tortorella, Sara; Goracci, Laura; Cecchetti, Violetta; Loregian, Arianna; Tabarrini, Oriana | |
| Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity | 2017 | Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Letizia Barreca, Maria; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana | |
| 2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors | 2018 | Nkizinkiko, Yves; Desantis, Jenny; Koivunen, Jarkko; Teemu, Haikarainen; Murthy, Sudarshan; Sancineto, Luca; Massari, Serena; Ianni, Federica; Obaji, Ezeogo; Loza Maria, I; Pihlajaniemi, Taina; Brea, Jose; Tabarrini, Oriana; Lehtiö, Lari | |
| Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder. | 2018 | Matthes, F; Massari, S; Bochicchio, A; Schorpp, K; Schilling, J; Weber, S; Offermann, N; Desantis, J; Wanker, E; Carloni, P; Hadian, K; Tabarrini, O; Rossetti, G; Krauss, S | |
| 4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10 | 2018 | Murthy, S; Desantis, J; Verheugd, P; Maksimainen, Mm; Venkannagari, H; Massari, S; Ashok, Y; Obaji, E; Nkizinkinko, Y; Lüscher, B; Tabarrini, O; Lehtiö, L | |
| From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors | 2019 | Massari, Serena; Corona, Angela; Distinto, Simona; Desantis, Jenny; Caredda, Alessia; Sabatini, Stefano; Manfroni, Giuseppe; Felicetti, Tommaso; Cecchetti, Violetta; Pannecouque, Christophe; Maccioni, Elias; Tramontano, Enzo; Tabarrini, Oriana | |
| Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance | 2019 | Nannetti, G.; Massari, S.; Mercorelli, B.; Bertagnin, C.; Desantis, J.; Palù, G.; Tabarrini, O.; Loregian, A. | |
| Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. | 2019 | Desantis, J.; Massari, S.; Sosic, A.; Manfroni, G.; Cannalire, R.; Felicetti, T.; Pannecouque, P.; Gatto, B.; Tabarrini, O. | |
| 1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity | 2020 | Desantis, J.; Massari, S.; Corona, A.; Astolfi, A.; Sabatini, S.; Manfroni, G.; Palazzotti, D.; Cecchetti, V.; Pannecouque, C.; Tramontano, E.; Tabarrini, O. | |
| Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications | 2020 | Goracci, L.; Desantis, J.; Valeri, A.; Castellani, B.; Eleuteri, M.; Cruciani, G. | |
| Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors | 2020 | Nizi, M. G.; Desantis, J.; Nakatani, Y.; Massari, S.; Mazzarella, M. A.; Shetye, G.; Sabatini, S.; Barreca, M. L.; Manfroni, G.; Felicetti, T.; Rushton-Green, R.; Hards, K.; Latacz, G.; Satala, G.; Bojarski, A. J.; Cecchetti, V.; Kolar, M. H.; Handzlik, J.; Cook, G. M.; Franzblau, S. G.; Tabarrini, O. | |
| Effects of MTX-23, a novel PROTAC of androgen receptor splice variant-7 and androgen receptor, on CRPC resistant to second-line antiandrogen therapy | 2021 | Lee, G. T.; Nagaya, N.; Desantis, J.; Madura, K.; Sabaawy, H. E.; Kim, W. -J.; Vaz, R. J.; Cruciani, G.; Kim, I. Y. | |
| Indomethacin-based PROTACs as pan-coronavirus antiviral agents | 2021 | Desantis, J.; Mercorelli, B.; Celegato, M.; Croci, F.; Bazzacco, A.; Baroni, M.; Siragusa, L.; Cruciani, G.; Loregian, A.; Goracci, L. | |
| Automatic Identification of Lansoprazole Degradants under Stress Conditions by LC-HRMS with MassChemSite and WebChembase | 2021 | Bonciarelli, S.; Desantis, J.; Goracci, L.; Siragusa, L.; Zamora, I.; Ortega-Carrasco, E. | |
| Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions | 2021 | Massari, S.; Desantis, J.; Nizi, M. G.; Cecchetti, V.; Tabarrini, O. |
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