Sfoglia per Autore
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains
2007 Barreca, MARIA LETIZIA; Rao, A.; De Luca, L.; Iraci, Nunzio; Monforte, A. M.; Maga, G.; De Clercq, E.; Pannecouque, C.; Balzarini, J.; Chimirri, A.
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors.
2007 Barreca, MARIA LETIZIA; DE LUCA, L; Iraci, Nunzio; Rao, A; Ferro, S; Maga, G; Chimirri, A.
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin.
2008 Stancanelli, R; Crupi, V; DE LUCA, L; Ficarra, P; Ficarra, R; Gitto, R; Guardo, M; Iraci, Nunzio; Majolino, D; Tommasini, S; Venuti, V.
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions
2008 Stefania, Ferro; LAURA DE, Luca; Barreca, MARIA LETIZIA; Iraci, Nunzio; SARA DE, Grazia; Zeger, Debyser; Myriam, Witvrouw; Alba, Chimirri
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS
2008 Stefania, Ferro; LAURA DE, Luca; Barreca, MARIA LETIZIA; Iraci, Nunzio; Rosaria, Gitto; ANNA MARIA, Monforte; Frauke, Christ; Zeger, Debyser; Alba, Chimirri
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS
2008 Stefania, Ferro; LAURA DE, Luca; SARA DE, Grazia; Barreca, MARIA LETIZIA; Iraci, Nunzio; Frauke, Christ; Zeger, Debyser; Alba, Chimirri
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors
2008 LAURA DE, Luca; Barreca, MARIA LETIZIA; Stefania, Ferro; Iraci, Nunzio; Zeger, Debyser; MYRIAM WITVROUW AND ALBA, Chimirri
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs)
2008 Patrizia, Logoteta; Iraci, Nunzio; LAURA DE, Luca; Stefania, Ferro; ERIK DE, Clercq; Giovanni, Maga; Alba, Chimirri; ANNA MARIA, Monforte
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors.
2008 Monforte, Am; Rao, A; Logoteta, P; Ferro, S; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; Maga, G; DE CLERCQ, E; Pannecouque, C; Chimirri, A.
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.
2008 DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Michiels, M; Christ, F; Debyser, Z; Witvrouw, M; Chimirri, A.
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents
2009 Logoteta, P; Iraci, Nunzio; DE LUCA, L; Ferro, S; DE CLERCQ, E; Maga, G; Chimirri, A; Monforte, A. M.
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.
2009 Monforte, A. M.; Logoteta, P.; Ferro, S.; De Luca, L.; Iraci, Nunzio; Maga, G.; De Clercq, E.; Pannecouque, C.; Chimirri, A.
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy
2009 DE LUCA, L; Ferro, S; Agnello, S; Gitto, R; Monforte, A. M.; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z; Chimirri, A.
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction
2009 Ferro, S; DE LUCA, L; Agnello, S; Barreca, MARIA LETIZIA; Iraci, Nunzio; Gitto, R; Monforte, A. M.; Christ, F; Debyser, Z; Chimirri, A.
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi
2009 Meschini, Francesco; Manfroni, Giuseppe; Sabatini, Stefano; Iraci, Nunzio; Cecchetti, Violetta
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research
2009 Chimirri, A; DE CLERCQ, E; Maga, G; Logoteta, P; Ferro, S; DE LUCA, L; Iraci, Nunzio; Pannecouque, C; Monforte, A. M.
From 3D-pharmacophore models to synthetic route towards anti-HIV agents
2009 Chimirri, A; DE LUCA, L; Ferro, S; Agnello, S; DE GRAZIA, S; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z.
Docking studies on a new HIV integrase–Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions
2009 Ferro, S; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; DE GRAZIA, S; Christ, F; Witvrouw, M; Debyser, Z; Chimirri, A.
Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
2009 DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Christ, F; Iraci, Nunzio; Gitto, R; Monforte, Am; Debyser, Z; Chimirri, A.
Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors. ChemMedChem
2009 Barreca, MARIA LETIZIA; Iraci, Nunzio; DE LUCA, L; Chimirri, A.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains | 2007 | Barreca, MARIA LETIZIA; Rao, A.; De Luca, L.; Iraci, Nunzio; Monforte, A. M.; Maga, G.; De Clercq, E.; Pannecouque, C.; Balzarini, J.; Chimirri, A. | |
| Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. | 2007 | Barreca, MARIA LETIZIA; DE LUCA, L; Iraci, Nunzio; Rao, A; Ferro, S; Maga, G; Chimirri, A. | |
| Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin. | 2008 | Stancanelli, R; Crupi, V; DE LUCA, L; Ficarra, P; Ficarra, R; Gitto, R; Guardo, M; Iraci, Nunzio; Majolino, D; Tommasini, S; Venuti, V. | |
| HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions | 2008 | Stefania, Ferro; LAURA DE, Luca; Barreca, MARIA LETIZIA; Iraci, Nunzio; SARA DE, Grazia; Zeger, Debyser; Myriam, Witvrouw; Alba, Chimirri | |
| MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS | 2008 | Stefania, Ferro; LAURA DE, Luca; Barreca, MARIA LETIZIA; Iraci, Nunzio; Rosaria, Gitto; ANNA MARIA, Monforte; Frauke, Christ; Zeger, Debyser; Alba, Chimirri | |
| INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS | 2008 | Stefania, Ferro; LAURA DE, Luca; SARA DE, Grazia; Barreca, MARIA LETIZIA; Iraci, Nunzio; Frauke, Christ; Zeger, Debyser; Alba, Chimirri | |
| A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors | 2008 | LAURA DE, Luca; Barreca, MARIA LETIZIA; Stefania, Ferro; Iraci, Nunzio; Zeger, Debyser; MYRIAM WITVROUW AND ALBA, Chimirri | |
| Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) | 2008 | Patrizia, Logoteta; Iraci, Nunzio; LAURA DE, Luca; Stefania, Ferro; ERIK DE, Clercq; Giovanni, Maga; Alba, Chimirri; ANNA MARIA, Monforte | |
| Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. | 2008 | Monforte, Am; Rao, A; Logoteta, P; Ferro, S; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; Maga, G; DE CLERCQ, E; Pannecouque, C; Chimirri, A. | |
| A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series. | 2008 | DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Michiels, M; Christ, F; Debyser, Z; Witvrouw, M; Chimirri, A. | |
| Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents | 2009 | Logoteta, P; Iraci, Nunzio; DE LUCA, L; Ferro, S; DE CLERCQ, E; Maga, G; Chimirri, A; Monforte, A. M. | |
| Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. | 2009 | Monforte, A. M.; Logoteta, P.; Ferro, S.; De Luca, L.; Iraci, Nunzio; Maga, G.; De Clercq, E.; Pannecouque, C.; Chimirri, A. | |
| A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy | 2009 | DE LUCA, L; Ferro, S; Agnello, S; Gitto, R; Monforte, A. M.; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z; Chimirri, A. | |
| Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction | 2009 | Ferro, S; DE LUCA, L; Agnello, S; Barreca, MARIA LETIZIA; Iraci, Nunzio; Gitto, R; Monforte, A. M.; Christ, F; Debyser, Z; Chimirri, A. | |
| Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi | 2009 | Meschini, Francesco; Manfroni, Giuseppe; Sabatini, Stefano; Iraci, Nunzio; Cecchetti, Violetta | |
| Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research | 2009 | Chimirri, A; DE CLERCQ, E; Maga, G; Logoteta, P; Ferro, S; DE LUCA, L; Iraci, Nunzio; Pannecouque, C; Monforte, A. M. | |
| From 3D-pharmacophore models to synthetic route towards anti-HIV agents | 2009 | Chimirri, A; DE LUCA, L; Ferro, S; Agnello, S; DE GRAZIA, S; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z. | |
| Docking studies on a new HIV integrase–Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions | 2009 | Ferro, S; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; DE GRAZIA, S; Christ, F; Witvrouw, M; Debyser, Z; Chimirri, A. | |
| Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75. | 2009 | DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Christ, F; Iraci, Nunzio; Gitto, R; Monforte, Am; Debyser, Z; Chimirri, A. | |
| Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors. ChemMedChem | 2009 | Barreca, MARIA LETIZIA; Iraci, Nunzio; DE LUCA, L; Chimirri, A. |
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