ROTI, GIOVANNI
 Distribuzione geografica
Continente #
NA - Nord America 2.056
EU - Europa 1.245
AS - Asia 1.113
SA - Sud America 172
Continente sconosciuto - Info sul continente non disponibili 117
AF - Africa 39
Totale 4.742
Nazione #
US - Stati Uniti d'America 1.991
SG - Singapore 534
IE - Irlanda 240
IT - Italia 190
SE - Svezia 183
RU - Federazione Russa 176
CN - Cina 160
BR - Brasile 135
HK - Hong Kong 127
VN - Vietnam 123
FI - Finlandia 85
FR - Francia 77
UA - Ucraina 76
DE - Germania 66
GB - Regno Unito 55
CA - Canada 33
KR - Corea 25
IN - India 21
PL - Polonia 20
AR - Argentina 17
BD - Bangladesh 16
IQ - Iraq 16
RO - Romania 16
ZA - Sudafrica 16
JP - Giappone 14
NL - Olanda 14
PK - Pakistan 14
MX - Messico 13
TR - Turchia 13
CH - Svizzera 9
CZ - Repubblica Ceca 9
UZ - Uzbekistan 9
BE - Belgio 8
ES - Italia 7
JM - Giamaica 7
AT - Austria 6
JO - Giordania 6
CO - Colombia 5
MA - Marocco 5
SA - Arabia Saudita 5
EC - Ecuador 4
ET - Etiopia 4
VE - Venezuela 4
AM - Armenia 3
CI - Costa d'Avorio 3
CL - Cile 3
GR - Grecia 3
ID - Indonesia 3
KZ - Kazakistan 3
NP - Nepal 3
TN - Tunisia 3
AZ - Azerbaigian 2
BG - Bulgaria 2
CR - Costa Rica 2
HN - Honduras 2
IL - Israele 2
KW - Kuwait 2
LB - Libano 2
MY - Malesia 2
PE - Perù 2
PH - Filippine 2
SI - Slovenia 2
TT - Trinidad e Tobago 2
AE - Emirati Arabi Uniti 1
BB - Barbados 1
BS - Bahamas 1
BZ - Belize 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EG - Egitto 1
GE - Georgia 1
GT - Guatemala 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LT - Lituania 1
NG - Nigeria 1
NI - Nicaragua 1
OM - Oman 1
PY - Paraguay 1
RE - Reunion 1
RW - Ruanda 1
SC - Seychelles 1
UY - Uruguay 1
YT - Mayotte 1
Totale 4.625
Città #
Singapore 331
Chandler 248
Dublin 240
San Jose 185
San Mateo 164
Ashburn 131
Hong Kong 127
Boardman 82
Council Bluffs 80
Santa Clara 78
Moscow 67
Ann Arbor 61
Altamura 57
Perugia 57
Medford 55
Princeton 54
Dong Ket 53
Lauterbourg 48
Wilmington 48
Lawrence 44
Andover 38
Jacksonville 38
Beijing 32
The Dalles 31
Los Angeles 28
Ho Chi Minh City 27
New York 27
Helsinki 25
Seoul 25
Munich 22
Dallas 16
Orem 15
Saint Petersburg 15
Bucharest 14
São Paulo 14
Tokyo 14
Warsaw 14
Montreal 12
Turku 11
Frankfurt am Main 10
Nuremberg 10
Chicago 9
Johannesburg 9
Phoenix 9
Piscataway 9
Woodbridge 9
Assisi 8
Boston 8
Brussels 8
Chennai 8
Houston 8
Rio de Janeiro 8
Stockholm 8
Toronto 8
Hanoi 7
Norwalk 7
Amsterdam 6
Atlanta 6
Brooklyn 6
Charlotte 6
Dearborn 6
Des Moines 6
Kingston 6
Lahore 6
Milan 6
Amman 5
Baghdad 5
Belo Horizonte 5
London 5
Olomouc 5
Poplar 5
Tashkent 5
Ankara 4
Augusta 4
Bastia 4
City of London 4
Frankfurt Am Main 4
Haiphong 4
Mexico City 4
San Francisco 4
San Paolo di Civitate 4
Shanghai 4
Abidjan 3
Addis Ababa 3
Auburn Hills 3
Brno 3
Buenos Aires 3
Buffalo 3
Casablanca 3
Curitiba 3
Da Nang 3
Denver 3
Guangzhou 3
Istanbul 3
Manchester 3
Mumbai 3
Naples 3
New Orleans 3
Sorocaba 3
Anshun 2
Totale 2.953
Nome #
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 187
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. 178
Acute lymphoblastic leukaemia in Noonan syndrome 136
Constitutive phosphorylation of Janus kinase2 in the GL15 glioblastoma derived human cell line 133
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 119
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML) 116
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome 114
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia 113
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. 113
DHPLC analysis of NPM1 mutations in adult primary AML. 108
Bone marrow endothelial cells carry BCR/ABL fusion gene from chronic myeloid leukemia patients. 108
e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia 108
Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia 108
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 107
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY 106
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype 104
Genetic pathways in low-and high-grade HCV-related lymphomas are different 102
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo 100
Different genomic imbalances in low- and high-grade HCV-related lymphomas 99
Angiopoietins expression by human myeloma cells. 97
Denaturing high performance liquid chromatography analysis of npm1 mutations in adult primary acute myeloid leukemia. 91
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 89
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 89
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement 87
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in Acute Myeloid Leukemia 87
Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML 86
Mutational analisys of JAK2 VAL617PHE in a new series of chronic myelomonocytic leukemia and related atypical myeloproliferative disorders 79
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML). 76
Hematologic malignancies with extramedullary spread of disease. Case 1. Multiple myeloma with extramedullary involvement of the pleura and testes. 75
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia. 73
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 71
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 69
Molecular cytogenetic studies of myelodysplastic/ myloproliferative disease. 69
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 67
NPM1 monoallelic deletion in a subgroup of MDS/AML with del(5q) or monosomy 5 and complex karyotype 65
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies 65
NPM1 gene mutations in acute myeloid leukemia. 65
Multiple Myeloma Patient with unusual extramedullary involvement 63
Il-7 is induced by il-6 in human myeloma cells: role in multiple myeloma. 62
NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 62
Genetic profile of acute lymphoblastic leukemia in a patient with the noonan syndrome 59
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines. 59
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype. 58
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 56
Human myeloma cells express IL-7 mRNA and secrete IL-7 in presence of IL-6. 56
Human myeloma cells produce angiopoietin-1 but not angiopoietin-2: Potential relationship with myeloma-induced angiogenesis 56
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. 55
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 54
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma. 52
Modulating Notch1 With Signature-based Small Molecule Library Screening 49
Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis. 49
Identification of AML1-ETO modulators by chemical genomics. 48
Osteopontin is produced by human multiple myeloma cells. 47
Targeting NOTCH1 in hematopoietic malignancy. 46
New Approaches to Target T-ALL 45
Genetic and proteomic approaches to identify cancer drug targets. 35
BIALLELIC LOSS OF RB1 AND LPAR6 AT 13Q14 DRIVES KEY CELL CYCLE ABNORMALITIES IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA 29
Deregulation of FOXF1/FENDRR from t(14;16)(q32;q24) defines a subtype of high-risk lineage ambiguous leukemia 18
COMBINED NF1/SUZ12 HAPLOINSUFFICIENCY DRIVES ABERRANT ACTIVATION OF THE RAS SIGNALING CASCADE IN IMMATURE HOXA-POSITIVE T-ALL 14
Ex vivo drug response profiling guides therapy in a case of high-risk acute undifferentiated leukemia with PICALM::MLLT10 11
Totale 4.742
Categoria #
all - tutte 23.448
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.448


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022392 0 0 0 30 24 3 1 158 7 22 71 76
2022/2023780 56 155 5 72 47 76 0 38 308 0 19 4
2023/2024312 27 26 20 12 2 3 63 0 19 10 44 86
2024/2025676 16 72 37 21 110 19 14 47 127 40 111 62
2025/20261.436 96 90 68 205 213 123 241 69 142 146 29 14
2026/2027362 30 48 89 195 0 0 0 0 0 0 0 0
Totale 4.742