IRIS - Res&Arch Institutional Research Information System - Research & Archive

ROTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 1.476
EU - Europa 1.088
AS - Asia 903
SA - Sud America 135
AF - Africa 20
Totale 3.622
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Nazione #
US - Stati Uniti d'America 1.449
SG - Singapore 440
IE - Irlanda 239
SE - Svezia 183
IT - Italia 163
CN - Cina 147
RU - Federazione Russa 128
HK - Hong Kong 127
BR - Brasile 119
VN - Vietnam 101
FI - Finlandia 85
UA - Ucraina 73
DE - Germania 61
GB - Regno Unito 47
KR - Corea 25
PL - Polonia 19
FR - Francia 18
RO - Romania 16
CA - Canada 13
NL - Olanda 13
JP - Giappone 12
ZA - Sudafrica 10
CH - Svizzera 9
CZ - Repubblica Ceca 9
MX - Messico 9
AR - Argentina 8
BE - Belgio 7
IQ - Iraq 7
UZ - Uzbekistan 7
AT - Austria 6
ES - Italia 5
TR - Turchia 5
BD - Bangladesh 4
IN - India 4
PK - Pakistan 4
CO - Colombia 3
GR - Grecia 3
IL - Israele 3
JO - Giordania 3
AM - Armenia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
EC - Ecuador 2
ET - Etiopia 2
ID - Indonesia 2
LB - Libano 2
MA - Marocco 2
PE - Perù 2
BB - Barbados 1
BS - Bahamas 1
GE - Georgia 1
HN - Honduras 1
JM - Giamaica 1
KE - Kenya 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LT - Lituania 1
MY - Malesia 1
NI - Nicaragua 1
NP - Nepal 1
OM - Oman 1
RE - Reunion 1
RW - Ruanda 1
SI - Slovenia 1
VE - Venezuela 1
YT - Mayotte 1
Totale 3.622
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Città #
Singapore 259
Chandler 248
Dublin 239
San Mateo 164
Hong Kong 127
Boardman 82
Ashburn 74
Santa Clara 68
Ann Arbor 61
Altamura 57
Medford 55
Perugia 54
Princeton 54
Dong Ket 53
Wilmington 48
Lawrence 44
Moscow 40
Andover 38
Jacksonville 38
Beijing 32
Seoul 25
Helsinki 24
Munich 24
Ho Chi Minh City 22
Los Angeles 20
New York 16
Saint Petersburg 15
Bucharest 14
Warsaw 13
The Dalles 12
Tokyo 12
Turku 12
Council Bluffs 11
Nuremberg 9
Woodbridge 9
Assisi 8
Boston 8
Johannesburg 8
Stockholm 8
São Paulo 8
Brussels 7
Houston 7
Montreal 7
Norwalk 7
Orem 7
Rio de Janeiro 7
Amsterdam 6
Dallas 6
Dearborn 6
Des Moines 6
Piscataway 6
Belo Horizonte 5
Brooklyn 5
Chicago 5
Hanoi 5
Olomouc 5
Poplar 5
Atlanta 4
Bastia 4
Frankfurt Am Main 4
Frankfurt am Main 4
London 4
Mexico City 4
Phoenix 4
San Francisco 4
San Jose 4
San Paolo di Civitate 4
Amman 3
Auburn Hills 3
Augusta 3
Brno 3
City of London 3
Curitiba 3
Denver 3
Falkenstein 3
Guangzhou 3
Haiphong 3
Shanghai 3
Sorocaba 3
Tashkent 3
Tel Aviv 3
Abidjan 2
Ankara 2
Anshun 2
Baghdad 2
Baku 2
Bexley 2
Biên Hòa 2
Bogotá 2
Charlotte 2
Chennai 2
Contagem 2
Da Nang 2
Den Haag 2
Erbil 2
Falls Church 2
Florianópolis 2
Foligno 2
Goiânia 2
Guernica 2
Totale 2.335
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Nome #
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 159
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. 157
Acute lymphoblastic leukaemia in Noonan syndrome 120
Constitutive phosphorylation of Janus kinase2 in the GL15 glioblastoma derived human cell line 109
Bone marrow endothelial cells carry BCR/ABL fusion gene from chronic myeloid leukemia patients. 99
e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia 99
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia 95
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML) 92
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 88
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 87
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome 87
Different genomic imbalances in low- and high-grade HCV-related lymphomas 85
Genetic pathways in low-and high-grade HCV-related lymphomas are different 85
Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia 84
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype 83
DHPLC analysis of NPM1 mutations in adult primary AML. 83
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY 83
Angiopoietins expression by human myeloma cells. 79
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. 79
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo 73
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 72
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 71
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement 67
Denaturing high performance liquid chromatography analysis of npm1 mutations in adult primary acute myeloid leukemia. 66
null 63
Mutational analisys of JAK2 VAL617PHE in a new series of chronic myelomonocytic leukemia and related atypical myeloproliferative disorders 61
Hematologic malignancies with extramedullary spread of disease. Case 1. Multiple myeloma with extramedullary involvement of the pleura and testes. 60
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML). 57
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia. 57
Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML 56
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 56
NPM1 monoallelic deletion in a subgroup of MDS/AML with del(5q) or monosomy 5 and complex karyotype 55
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 55
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 54
Molecular cytogenetic studies of myelodysplastic/ myloproliferative disease. 53
Multiple Myeloma Patient with unusual extramedullary involvement 52
Il-7 is induced by il-6 in human myeloma cells: role in multiple myeloma. 50
Genetic profile of acute lymphoblastic leukemia in a patient with the noonan syndrome 49
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies 48
NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 48
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype. 48
Human myeloma cells express IL-7 mRNA and secrete IL-7 in presence of IL-6. 45
Human myeloma cells produce angiopoietin-1 but not angiopoietin-2: Potential relationship with myeloma-induced angiogenesis 45
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines. 45
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma. 42
NPM1 gene mutations in acute myeloid leukemia. 42
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 41
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. 40
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 40
Identification of AML1-ETO modulators by chemical genomics. 39
Modulating Notch1 With Signature-based Small Molecule Library Screening 38
Targeting NOTCH1 in hematopoietic malignancy. 38
Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis. 37
Osteopontin is produced by human multiple myeloma cells. 36
New Approaches to Target T-ALL 34
Genetic and proteomic approaches to identify cancer drug targets. 25
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in Acute Myeloid Leukemia 22
Totale 3.733
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Categoria #
all - tutte 18.711
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.711
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021163 0 0 0 0 0 28 13 3 27 13 18 61
2021/2022527 9 115 11 30 24 3 1 158 7 22 71 76
2022/2023780 56 155 5 72 47 76 0 38 308 0 19 4
2023/2024312 27 26 20 12 2 3 63 0 19 10 44 86
2024/2025686 16 72 37 21 110 21 14 49 128 40 113 65
2025/2026779 98 91 70 206 218 96 0 0 0 0 0 0
Totale 3.733