ROTI, GIOVANNI
 Distribuzione geografica
Continente #
NA - Nord America 1.800
EU - Europa 1.230
AS - Asia 1.106
SA - Sud America 162
Continente sconosciuto - Info sul continente non disponibili 117
AF - Africa 39
Totale 4.454
Nazione #
US - Stati Uniti d'America 1.746
SG - Singapore 532
IE - Irlanda 240
SE - Svezia 183
IT - Italia 178
RU - Federazione Russa 176
CN - Cina 160
BR - Brasile 127
HK - Hong Kong 127
VN - Vietnam 122
FI - Finlandia 85
FR - Francia 77
UA - Ucraina 76
DE - Germania 66
GB - Regno Unito 53
CA - Canada 26
KR - Corea 25
IN - India 21
PL - Polonia 19
AR - Argentina 16
BD - Bangladesh 16
IQ - Iraq 16
RO - Romania 16
ZA - Sudafrica 16
NL - Olanda 14
PK - Pakistan 14
JP - Giappone 13
MX - Messico 13
TR - Turchia 13
CH - Svizzera 9
CZ - Repubblica Ceca 9
UZ - Uzbekistan 9
BE - Belgio 8
ES - Italia 7
AT - Austria 6
JO - Giordania 6
CO - Colombia 5
JM - Giamaica 5
MA - Marocco 5
ET - Etiopia 4
SA - Arabia Saudita 4
VE - Venezuela 4
CI - Costa d'Avorio 3
CL - Cile 3
EC - Ecuador 3
GR - Grecia 3
ID - Indonesia 3
KZ - Kazakistan 3
NP - Nepal 3
TN - Tunisia 3
AM - Armenia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
CR - Costa Rica 2
HN - Honduras 2
IL - Israele 2
KW - Kuwait 2
LB - Libano 2
MY - Malesia 2
PE - Perù 2
SI - Slovenia 2
AE - Emirati Arabi Uniti 1
BB - Barbados 1
BS - Bahamas 1
BZ - Belize 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EG - Egitto 1
GE - Georgia 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LT - Lituania 1
NG - Nigeria 1
NI - Nicaragua 1
OM - Oman 1
PH - Filippine 1
PY - Paraguay 1
RE - Reunion 1
RW - Ruanda 1
SC - Seychelles 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
YT - Mayotte 1
Totale 4.337
Città #
Singapore 331
Chandler 248
Dublin 240
San Mateo 164
San Jose 147
Hong Kong 127
Ashburn 105
Boardman 82
Santa Clara 75
Moscow 67
Ann Arbor 61
Altamura 57
Perugia 57
Medford 55
Princeton 54
Dong Ket 53
Lauterbourg 48
Wilmington 48
Lawrence 44
Andover 38
Jacksonville 38
Beijing 32
The Dalles 31
Ho Chi Minh City 27
Los Angeles 27
Helsinki 25
Seoul 25
New York 23
Munich 22
Council Bluffs 15
Orem 15
Saint Petersburg 15
Bucharest 14
Tokyo 13
Warsaw 13
Montreal 12
Turku 11
Frankfurt am Main 10
Nuremberg 10
Johannesburg 9
Piscataway 9
Woodbridge 9
Assisi 8
Boston 8
Brussels 8
Chennai 8
Houston 8
Rio de Janeiro 8
Stockholm 8
São Paulo 8
Dallas 7
Norwalk 7
Amsterdam 6
Atlanta 6
Brooklyn 6
Chicago 6
Dearborn 6
Des Moines 6
Hanoi 6
Lahore 6
Amman 5
Baghdad 5
Belo Horizonte 5
Charlotte 5
Kingston 5
London 5
Milan 5
Olomouc 5
Phoenix 5
Poplar 5
Tashkent 5
Toronto 5
Ankara 4
Augusta 4
Bastia 4
City of London 4
Frankfurt Am Main 4
Haiphong 4
Mexico City 4
San Francisco 4
San Paolo di Civitate 4
Shanghai 4
Abidjan 3
Addis Ababa 3
Auburn Hills 3
Brno 3
Buenos Aires 3
Buffalo 3
Casablanca 3
Curitiba 3
Da Nang 3
Denver 3
Guangzhou 3
Istanbul 3
Manchester 3
Mumbai 3
Sorocaba 3
Anshun 2
Baku 2
Beccar 2
Totale 2.783
Nome #
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 183
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. 174
Acute lymphoblastic leukaemia in Noonan syndrome 132
Constitutive phosphorylation of Janus kinase2 in the GL15 glioblastoma derived human cell line 130
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML) 111
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 110
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome 109
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia 107
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. 107
Bone marrow endothelial cells carry BCR/ABL fusion gene from chronic myeloid leukemia patients. 105
e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia 105
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 104
Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia 104
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY 100
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype 99
Different genomic imbalances in low- and high-grade HCV-related lymphomas 98
Genetic pathways in low-and high-grade HCV-related lymphomas are different 98
DHPLC analysis of NPM1 mutations in adult primary AML. 96
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo 95
Angiopoietins expression by human myeloma cells. 93
Denaturing high performance liquid chromatography analysis of npm1 mutations in adult primary acute myeloid leukemia. 85
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 85
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 83
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement 81
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in Acute Myeloid Leukemia 81
Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML 80
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML). 73
Hematologic malignancies with extramedullary spread of disease. Case 1. Multiple myeloma with extramedullary involvement of the pleura and testes. 72
Mutational analisys of JAK2 VAL617PHE in a new series of chronic myelomonocytic leukemia and related atypical myeloproliferative disorders 69
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia. 69
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 67
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 65
NPM1 monoallelic deletion in a subgroup of MDS/AML with del(5q) or monosomy 5 and complex karyotype 64
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 63
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies 62
Molecular cytogenetic studies of myelodysplastic/ myloproliferative disease. 61
NPM1 gene mutations in acute myeloid leukemia. 61
Il-7 is induced by il-6 in human myeloma cells: role in multiple myeloma. 60
NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 59
Multiple Myeloma Patient with unusual extramedullary involvement 59
Genetic profile of acute lymphoblastic leukemia in a patient with the noonan syndrome 57
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines. 55
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype. 54
Human myeloma cells produce angiopoietin-1 but not angiopoietin-2: Potential relationship with myeloma-induced angiogenesis 53
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 52
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. 52
Human myeloma cells express IL-7 mRNA and secrete IL-7 in presence of IL-6. 52
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 51
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma. 48
Modulating Notch1 With Signature-based Small Molecule Library Screening 46
Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis. 45
Identification of AML1-ETO modulators by chemical genomics. 45
Osteopontin is produced by human multiple myeloma cells. 44
Targeting NOTCH1 in hematopoietic malignancy. 42
New Approaches to Target T-ALL 42
Genetic and proteomic approaches to identify cancer drug targets. 32
BIALLELIC LOSS OF RB1 AND LPAR6 AT 13Q14 DRIVES KEY CELL CYCLE ABNORMALITIES IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA 10
Deregulation of FOXF1/FENDRR from t(14;16)(q32;q24) defines a subtype of high-risk lineage ambiguous leukemia 10
Ex vivo drug response profiling guides therapy in a case of high-risk acute undifferentiated leukemia with PICALM::MLLT10 4
COMBINED NF1/SUZ12 HAPLOINSUFFICIENCY DRIVES ABERRANT ACTIVATION OF THE RAS SIGNALING CASCADE IN IMMATURE HOXA-POSITIVE T-ALL 1
Totale 4.454
Categoria #
all - tutte 22.250
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.250


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022518 0 115 11 30 24 3 1 158 7 22 71 76
2022/2023780 56 155 5 72 47 76 0 38 308 0 19 4
2023/2024312 27 26 20 12 2 3 63 0 19 10 44 86
2024/2025676 16 72 37 21 110 19 14 47 127 40 111 62
2025/20261.436 96 90 68 205 213 123 241 69 142 146 29 14
2026/202774 30 44 0 0 0 0 0 0 0 0 0 0
Totale 4.454