ROTI, GIOVANNI
 Distribuzione geografica
Continente #
NA - Nord America 1.699
EU - Europa 1.212
AS - Asia 1.104
SA - Sud America 157
AF - Africa 37
Totale 4.209
Nazione #
US - Stati Uniti d'America 1.659
SG - Singapore 531
IE - Irlanda 240
SE - Svezia 183
RU - Federazione Russa 176
IT - Italia 166
CN - Cina 160
HK - Hong Kong 127
BR - Brasile 124
VN - Vietnam 122
FI - Finlandia 85
FR - Francia 75
UA - Ucraina 75
DE - Germania 66
GB - Regno Unito 52
KR - Corea 25
IN - India 21
PL - Polonia 19
CA - Canada 17
IQ - Iraq 16
RO - Romania 16
AR - Argentina 15
BD - Bangladesh 15
ZA - Sudafrica 15
PK - Pakistan 14
JP - Giappone 13
MX - Messico 13
NL - Olanda 13
TR - Turchia 13
CH - Svizzera 9
CZ - Repubblica Ceca 9
UZ - Uzbekistan 9
BE - Belgio 7
ES - Italia 7
AT - Austria 6
JO - Giordania 6
CO - Colombia 5
JM - Giamaica 5
MA - Marocco 5
ET - Etiopia 4
SA - Arabia Saudita 4
VE - Venezuela 4
CI - Costa d'Avorio 3
EC - Ecuador 3
GR - Grecia 3
ID - Indonesia 3
KZ - Kazakistan 3
NP - Nepal 3
TN - Tunisia 3
AM - Armenia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
CL - Cile 2
IL - Israele 2
KW - Kuwait 2
LB - Libano 2
MY - Malesia 2
PE - Perù 2
SI - Slovenia 2
AE - Emirati Arabi Uniti 1
BB - Barbados 1
BS - Bahamas 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EG - Egitto 1
GE - Georgia 1
HN - Honduras 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LT - Lituania 1
NG - Nigeria 1
NI - Nicaragua 1
OM - Oman 1
PH - Filippine 1
PY - Paraguay 1
RE - Reunion 1
RW - Ruanda 1
UY - Uruguay 1
YT - Mayotte 1
Totale 4.209
Città #
Singapore 331
Chandler 248
Dublin 240
San Mateo 164
San Jose 133
Hong Kong 127
Ashburn 101
Boardman 82
Santa Clara 70
Moscow 67
Ann Arbor 61
Altamura 57
Medford 55
Perugia 54
Princeton 54
Dong Ket 53
Lauterbourg 48
Wilmington 48
Lawrence 44
Andover 38
Jacksonville 38
Beijing 32
The Dalles 31
Ho Chi Minh City 27
Helsinki 25
Seoul 25
Munich 22
Los Angeles 20
New York 17
Council Bluffs 15
Saint Petersburg 15
Bucharest 14
Orem 14
Tokyo 13
Warsaw 13
Turku 11
Frankfurt am Main 10
Nuremberg 10
Johannesburg 9
Woodbridge 9
Assisi 8
Boston 8
Chennai 8
Montreal 8
Piscataway 8
Stockholm 8
São Paulo 8
Brussels 7
Dallas 7
Houston 7
Norwalk 7
Rio de Janeiro 7
Amsterdam 6
Chicago 6
Dearborn 6
Des Moines 6
Hanoi 6
Lahore 6
Amman 5
Atlanta 5
Baghdad 5
Belo Horizonte 5
Brooklyn 5
Kingston 5
Olomouc 5
Poplar 5
Tashkent 5
Ankara 4
Augusta 4
Bastia 4
City of London 4
Frankfurt Am Main 4
Haiphong 4
London 4
Mexico City 4
Milan 4
Phoenix 4
San Francisco 4
San Paolo di Civitate 4
Shanghai 4
Abidjan 3
Addis Ababa 3
Auburn Hills 3
Brno 3
Buenos Aires 3
Casablanca 3
Curitiba 3
Da Nang 3
Denver 3
Guangzhou 3
Istanbul 3
Manchester 3
Mumbai 3
Sorocaba 3
Toronto 3
Anshun 2
Baku 2
Beccar 2
Bexley 2
Biên Hòa 2
Totale 2.724
Nome #
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 179
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. 172
Acute lymphoblastic leukaemia in Noonan syndrome 129
Constitutive phosphorylation of Janus kinase2 in the GL15 glioblastoma derived human cell line 126
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 109
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML) 107
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia 106
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome 106
Bone marrow endothelial cells carry BCR/ABL fusion gene from chronic myeloid leukemia patients. 105
e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia 104
Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia 103
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. 103
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 101
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY 99
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype 97
Different genomic imbalances in low- and high-grade HCV-related lymphomas 96
DHPLC analysis of NPM1 mutations in adult primary AML. 94
Genetic pathways in low-and high-grade HCV-related lymphomas are different 94
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo 91
Angiopoietins expression by human myeloma cells. 89
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 82
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 80
Denaturing high performance liquid chromatography analysis of npm1 mutations in adult primary acute myeloid leukemia. 79
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement 79
Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML 76
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in Acute Myeloid Leukemia 75
Hematologic malignancies with extramedullary spread of disease. Case 1. Multiple myeloma with extramedullary involvement of the pleura and testes. 72
Mechanism of altered nucleo-cytoplasmic traffic of nucleophosmin in acute myelogenous leukemia carrying exon12 NPM mutations (NPMc plus AML). 69
Mutational analisys of JAK2 VAL617PHE in a new series of chronic myelomonocytic leukemia and related atypical myeloproliferative disorders 68
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia. 68
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 66
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 64
NPM1 monoallelic deletion in a subgroup of MDS/AML with del(5q) or monosomy 5 and complex karyotype 63
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 63
Molecular cytogenetic studies of myelodysplastic/ myloproliferative disease. 61
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies 61
NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 59
NPM1 gene mutations in acute myeloid leukemia. 59
Il-7 is induced by il-6 in human myeloma cells: role in multiple myeloma. 58
Multiple Myeloma Patient with unusual extramedullary involvement 58
Genetic profile of acute lymphoblastic leukemia in a patient with the noonan syndrome 56
Quantitative detection of NPM1 mutations as marker of minimal residual disease (MRD) in the large majority of AML with normal karyotype. 54
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines. 53
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 52
Human myeloma cells produce angiopoietin-1 but not angiopoietin-2: Potential relationship with myeloma-induced angiogenesis 52
Human myeloma cells express IL-7 mRNA and secrete IL-7 in presence of IL-6. 51
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. 49
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 49
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma. 48
Identification of AML1-ETO modulators by chemical genomics. 45
Osteopontin is produced by human multiple myeloma cells. 44
Modulating Notch1 With Signature-based Small Molecule Library Screening 43
Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis. 43
New Approaches to Target T-ALL 41
Targeting NOTCH1 in hematopoietic malignancy. 40
Genetic and proteomic approaches to identify cancer drug targets. 32
Totale 4.322
Categoria #
all - tutte 19.921
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.921


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202192 0 0 0 0 0 0 0 0 0 13 18 61
2021/2022527 9 115 11 30 24 3 1 158 7 22 71 76
2022/2023780 56 155 5 72 47 76 0 38 308 0 19 4
2023/2024312 27 26 20 12 2 3 63 0 19 10 44 86
2024/2025676 16 72 37 21 110 19 14 47 127 40 111 62
2025/20261.378 96 90 68 205 213 123 241 69 142 131 0 0
Totale 4.322