IRIS - Res&Arch Institutional Research Information System - Research & Archive

SPORTOLETTI, PAOLO
 Distribuzione geografica
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Continente #
NA - Nord America 3.746
AS - Asia 3.066
EU - Europa 2.844
SA - Sud America 518
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 10.242
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Nazione #
US - Stati Uniti d'America 3.645
SG - Singapore 1.395
IT - Italia 945
IE - Irlanda 577
CN - Cina 501
HK - Hong Kong 456
BR - Brasile 437
VN - Vietnam 331
RU - Federazione Russa 269
DE - Germania 217
FI - Finlandia 166
SE - Svezia 138
KR - Corea 132
UA - Ucraina 125
GB - Regno Unito 81
IN - India 56
RO - Romania 50
CA - Canada 47
FR - Francia 45
MX - Messico 44
AT - Austria 41
AR - Argentina 35
NL - Olanda 32
TR - Turchia 32
PL - Polonia 31
BE - Belgio 30
BD - Bangladesh 26
UZ - Uzbekistan 24
CZ - Repubblica Ceca 21
JP - Giappone 21
ZA - Sudafrica 20
CH - Svizzera 17
LT - Lituania 17
ES - Italia 15
IQ - Iraq 14
EC - Ecuador 13
PE - Perù 10
PK - Pakistan 9
ID - Indonesia 8
CI - Costa d'Avorio 7
CL - Cile 7
IR - Iran 7
IL - Israele 6
AZ - Azerbaigian 5
KZ - Kazakistan 5
MA - Marocco 5
PT - Portogallo 5
EG - Egitto 4
JO - Giordania 4
KE - Kenya 4
LB - Libano 4
NP - Nepal 4
PH - Filippine 4
PY - Paraguay 4
SC - Seychelles 4
VE - Venezuela 4
AO - Angola 3
CO - Colombia 3
GR - Grecia 3
PA - Panama 3
PS - Palestinian Territory 3
SA - Arabia Saudita 3
TN - Tunisia 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
AL - Albania 2
BO - Bolivia 2
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
EU - Europa 2
GE - Georgia 2
IM - Isola di Man 2
KH - Cambogia 2
LV - Lettonia 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
UG - Uganda 2
AM - Armenia 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
CG - Congo 1
DJ - Gibuti 1
EE - Estonia 1
ET - Etiopia 1
GH - Ghana 1
HN - Honduras 1
HR - Croazia 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LY - Libia 1
ME - Montenegro 1
MK - Macedonia 1
MT - Malta 1
MZ - Mozambico 1
Totale 10.231
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Città #
Singapore 968
Chandler 594
Dublin 571
Perugia 478
Hong Kong 456
San Mateo 384
Ashburn 219
Boardman 207
Santa Clara 165
Dong Ket 140
Altamura 131
Seoul 129
Munich 117
Medford 107
Princeton 105
Lawrence 101
Beijing 94
Ann Arbor 81
Ho Chi Minh City 71
Moscow 71
New York 71
Los Angeles 68
Wilmington 66
Andover 63
Helsinki 59
Jacksonville 58
Turku 56
Piscataway 47
Bucharest 43
Hanoi 43
São Paulo 37
Brussels 30
Rome 30
Des Moines 27
Dearborn 26
Houston 26
Brooklyn 25
Redmond 25
The Dalles 25
Dallas 24
Foligno 23
Nuremberg 23
Vienna 22
Warsaw 22
Hefei 21
Tokyo 21
San Paolo di Civitate 20
Shanghai 20
Belo Horizonte 19
Mexico City 18
Norwalk 18
Amsterdam 17
Montreal 17
Redwood City 17
London 16
Assisi 15
Rio de Janeiro 15
San Francisco 15
Izmir 14
Saint Petersburg 14
Stockholm 14
Denver 13
Frankfurt am Main 13
Johannesburg 13
Orem 13
Tashkent 13
Atlanta 12
Chicago 12
Guangzhou 12
Haiphong 12
Menlo Park 12
Phoenix 12
Brno 11
Milan 11
Toronto 10
Chennai 9
Council Bluffs 9
Manchester 9
Poplar 9
Woodbridge 9
Ankara 8
Collazzone 8
Falkenstein 8
Falls Church 8
Abidjan 7
Boston 7
Changsha 7
Charlotte 7
Mumbai 7
San Jose 7
Tianjin 7
Tower Hamlets 7
Baghdad 6
Brasília 6
Cambridge 6
Curitiba 6
Dhaka 6
Fairfield 6
Ha Long 6
Nanning 6
Totale 6.769
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Nome #
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 160
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells 158
Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation. 153
Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice 148
Immune correlates of protection by vaccine against SARS-CoV-2 in patients with chronic lymphocytic leukaemia 145
Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity? 143
Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction 136
A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis 135
Activated autologous T cells exert an anti-B-cell chronic lymphatic leukemia effect in vitro and in vivo. 128
BCOR gene alterations in hematological diseases 123
ARSENIC TRIOXIDE AND ALL-TRANS-RETINOIC ACID TARGET NPM1 MUTANT ONCOPROTEIN LEVELS AND INDUCE APOPTOSIS IN NPM1-MUTATED AML CELLS 118
NOTCH1 Aberrations in Chronic Lymphocytic Leukemia. 116
Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita 115
Wnt/beta-Catenin Signaling Induces Integrin alpha 4 beta 1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice 114
Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL 114
NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models 113
Mesenchymal cells: a vehicle for gene therapy 112
Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives. 111
NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status 109
The NOTCH1/CD39 axis: A Treg trip-switch for GvHD 108
NPM1 AND FLT3-ITD MUTATIONS SINERGISTICALLY INDUCE GATA1 EPIGENETIC SILENCING IN A AML MOUSE MODEL 107
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia 107
NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications 107
Clinical-Grade Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell Dependent Graft-versus-Leukemia Effect in Murine Models 106
NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells. 104
GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations 103
The radiosensitizer Silver nanoparticles effects are prevent to ion channel blocker DIDS in U251 human glioblastoma cell line. 101
IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation. 100
Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice 99
A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice. 98
Blockade of Oncogenic NOTCH1 With the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia 98
CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity. 97
Human stromal cells engineered with interleukin-7 enhance the survival of naive T lymphocytes. 96
T regulatory cell separation for clinical application. 96
BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity 95
Dissecting Clonal Hematopoiesis in Tissues of Classical Hodgkin Lymphoma Patients 95
BRAF mutations in hairy-cell leukemia. 94
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML 94
NPM1 AND FLT3-ITD MUTATIONS COOPERATE TO IMPAIR HEMATOPOIETIC STEM/PROGENITOR CELLS DIFFERENTIATION AND DEREGULATE GATA1 IN A MOUSE MODEL OF AML 93
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. 92
A novel NOTCH1 PEST domain mutation in a case of Chronic Lymphocytic Leukemia 92
Mutant NPM1 Maintains the Leukemic State through HOX Expression 92
Richter's transformation in the heart 92
Isolation and characterization of a new human T regulatory cell subset from peripheral blood CD4+ T lymphocyte 90
Ibrutinib treatment of a patient with relapsing chronic lymphocytic leukemia and sustained remission of Richter syndrome 90
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 89
Interleukin-7-engineered mesenchymal cells: in vitro effects on naive T-cell population. 87
A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia 86
CURCUMIN EXHIBITS IN VITRO AND IN VIVO ANTI-LEUKEMIC ACTIVITY INTERFERING WITH THE NOTCH1 PATHWAY AND INDUCING ENDOPLASMIC RETICULUM STRESS IN CHRONIC LYMPHOCYTIC LEUKEMIA 83
NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL. 83
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model. 83
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY 83
Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML 83
Mutational landscape of AML with normal cytogenetics: biological and clinical implications 81
Comparison of ibrutinib and idelalisib plus rituximab in real-life relapsed/resistant chronic lymphocytic leukemia cases 81
Clinical-Grade Expanded Regulatory T Cells Are Enriched with Highly Suppressive Cells Producing IL-10, Granzyme B, and IL-35 81
Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia 81
Glucocorticoidi-Induced TNFR family Related gene (GITR) enhances dendritic cell activity 80
GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL 79
Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1-mutated AML 78
The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice 77
Identification and Characterization of Novel Rare Nucleophosmin (NPM1) Gene Mutations in Acute Myeloid Leukemia (AML) By a Combinatorial Approach of Immunohistochemistry and Molecular Analyses 75
Synthesis and characterization of UiO-66 metal-organic frameworks nanoparticles and their evaluation as drug delivery carriers in U251 glioblastoma cells 74
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo 74
NOTCH and NF-κB interplay in chronic lymphocytic leukemia is independent of genetic lesion. 73
Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL 72
Therapeutic Targeting Potential of Novel Silver Nanoparticles Coated with Anti-CD20 Antibody against Chronic Lymphocytic Leukemia 71
Interleukin 7-engineered stromal cells: a new approach for hastening naive T cell recruitment 71
Assessment of the 4-factor score: Retrospective analysis of 586 CLL patients receiving ibrutinib. A campus CLL study 71
A pro-inflammatory environment in bone marrow of Treg transplanted patients matches with graft-versus-leukemia effect 70
A NOVEL MECHANISM FOR NOTCH1 ACTIVATIONIN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS: INVOLVEMENT OF NOTCH1 ENDOSOMAL TRAFFICKING AND ALTERATIONS IN RAB PROTEINS 70
A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells 70
Mesenchymal cells recruit and regulate T regulatory cells. 70
A curious novel combination of nucleophosmin (Npm1) gene mutations leading to aberrant cytoplasmic dislocation of npm1 in acute myeloid leukemia (aml) 70
Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications 68
Uncommon lymphoplasmacytic lymphoma with IgA paraproteinemia: a challenging clinical diagnosis solved by MYD88 mutation analysis. 68
Functions of the native NPM1 protein and its leukemic mutant 67
Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation. 67
NPM1-mutated acute myeloid leukemia: from bench to bedside 67
NOTCH-1 ACTIVATION AND SUBCLONAL MUTATION NEGATIVELY IMPACT ON CHRONIC LYMPHOCYTIC LEUKEMIA OUTCOMES 65
FLT3-targeted therapy restores GATA1 pathway function in NPM1/FLT3-ITD mutated acute myeloid leukaemia 65
Catalase prevents DNA damage and cationic current activation by silver nanoparticles in U251 human glioblastoma cell line 64
Venetoclax in CLL patients who progress after B-cell Receptor inhibitor treatment: a retrospective multi-centre Italian experience 64
Prognostic Impact and Risk Factors of Infections in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib 63
A scale of "bad" co-mutations in NPM1-driven AML 62
Effectiveness of ibrutinib as first-line therapy for chronic lymphocytic leukemia patients and indirect comparison with rituximab-bendamustine: Results of study on 486 cases outside clinical trials 62
Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia. 61
A DYSREGULATED, DRUGGABLE PP2A/AKT/GSK3 beta AXIS SUSTAINS NOTCH1 SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS 60
NOTCH1-mutated chronic lymphocytic leukemia displays high endoplasmic reticulum stress response with druggable potential 60
Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation. 59
The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein 58
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis. 56
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia 55
Recurrent primary plasmacytoma of the eyelid with rapid regional metastasis. 55
NOTCH1 Aberrant Activation Is a Common Nonmutational Early Event in Chronic Lymphocytic Leukemia Hematopoietic Stem-Cells 54
The landscape of BRAF transcript and protein variants in human cancer. 54
Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics 53
NOTCH and Graft-Versus-Host Disease 53
The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model 52
Venetoclax-Rituximab Treatment of Relapsed/Refractory CLL During the COVID-19 Pandemic: A Real-Life Experience in Selected Central-Southern Italian Regions 52
Totale 8.807
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Categoria #
all - tutte 51.932
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.932
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021350 0 0 0 0 0 31 37 29 47 21 35 150
2021/20221.312 48 376 9 44 26 9 18 226 30 138 210 178
2022/20231.946 111 371 18 183 140 195 11 85 708 8 81 35
2023/2024918 40 81 52 35 6 24 282 10 52 31 137 168
2024/20252.398 77 195 63 81 293 142 211 172 478 109 366 211
2025/20262.698 360 303 237 597 741 460 0 0 0 0 0 0
Totale 10.676