PASQUALUCCI, Laura
PASQUALUCCI, Laura
DIPARTIMENTO DI MEDICINA E CHIRURGIA
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.
2007 Saito, M.; Gao, J.; Basso, K.; Kitagawa, Y.; Smith, P. M.; Bhagat, G.; Pernis, A.; Pasqualucci, Laura; Dalla Favera, R.
Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma.
2003 G., Gaidano; Pasqualucci, Laura; D., Capello; E., Berra; C., Deambrogi; D., Rossi; L. M., Larocca; A., Gloghini; A., Carbone; R., Dalla Favera
Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders.
2004 M., Cerri; D., Capello; G., Muti; A., Rambaldi; M., Paulli; A., Gloghini; E., Berra; C., Deambrogi; D., Rossi; S., Franceschetti; A., Conconi; E., Morra; Pasqualucci, Laura; A., Carbone; G., Gaidano
Aberrant somatic hypermutation in primary mediastinal large B-cell lymphoma.
2005 Rossi, D; Cerri, M; Capello, D; Deambrogi, C; Berra, E; Franceschetti, S; Alabiso, O; Gloghini, A; Paulli, M; Carbone, A; Pileri, Sa; Pasqualucci, Laura; Gaidano, G.
Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.
2006 D., Rossi; E., Berra; M., Cerri; C., Deambrogi; C., Barbieri; S., Franceschetti; M., Lunghi; A., Conconi; M., Paulli; A., Matolcsy; Pasqualucci, Laura; D., Capello; G., Gaidano
Aberrant somatic hypermutation in tumor cells of nodular lymphocyte-predominant and classical Hodgkin's lymphoma.
2006 Liso, A.; Capello, D.; Marafiori, T.; Tiacci, E.; Cerri, M.; Distler, V.; Paulli, M.; Carbone, A.; Delson, G.; Campo, E.; Pileri, S.; Pasqualucci, Laura; Gaidano, G.; Falini, B.
AID is required for germinal center-derived lymphomagenesis.
2008 Pasqualucci, Laura; Bhagat, G.; Jankovic, M.; Compagno, M.; Smith, P.; Muramatsu, M.; Honjo, T.; Morse H. C., Iii; Nussenzweig, M.; Dalla Favera, R.
Alterations of BIRC3 and multiple other NF-kB pathway genes in splenic marginal zone lymphoma
2011 Rossi, D; Deaglio, S; Dominguez Sola, D; Rasi, S; Vaisitti, T; Agostinelli, C; Spina, V; Bruscaggin, A; Monti, S; Cerri, M; Cresta, S; Fangazio, M; Arcaini, L; Lucioni, M; Marasca, R; Thieblemont, C; Capello, D; Facchetti, F; Kwee, I; Pileri, Sa; Foà, R; Bertoni, F; Dalla Favera, R; Pasqualucci, Laura; Gaidano, G.
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities
2021 Flümann, Ruth; Rehkämper, Tim; Nieper, Pascal; Pfeiffer, Pauline; Holzem, Alessandra; Klein, Sebastian; Bhatia, Sanil; Kochanek, Moritz; Kisis, Ilmars; Pelzer, Benedikt W; Ahlert, Heinz; Hauer, Julia; da Palma Guerreiro, Alexandra; Ryan, Jeremy A; Reimann, Maurice; Riabinska, Arina; Wiederstein, Janica; Krüger, Marcus; Deckert, Martina; Altmüller, Janine; Klatt, Andreas R; Frenzel, Lukas P; Pasqualucci, Laura; Béguelin, Wendy; Melnick, Ari M; Sander, Sandrine; Montesinos-Rongen, Manuel; Brunn, Anna; Lohneis, Philipp; Büttner, Reinhard; Kashkar, Hamid; Borkhardt, Arndt; Letai, Anthony; Persigehl, Thorsten; Peifer, Martin; Schmitt, Clemens A; Reinhardt, Hans Christian; Knittel, Gero
An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression
2015 Zhang, Baochun; Calado, Dinis Pedro; Wang, Zhe; Fröhler, Sebastian; Köchert, Karl; Qian, Yu; Koralov, Sergei B; Schmidt Supprian, Marc; Sasaki, Yoshiteru; Unitt, Christine; Rodig, Scott; Chen, Wei; Dalla Favera, Riccardo; Alt, Frederick W; Pasqualucci, Laura; Rajewsky, Klaus
Analysis of a 69-kb contiguous genomic sequence at a putative tumor suppressor gene locus on human chromosome 6q27.
1998 X. Y., Qu; R. S., Hauptschein; A., Rzhetsky; L., Scotto; M. C., Chien; X., Ye; F., Frigeri; P. H., Rao; Pasqualucci, Laura; B., Gamberi; L. L., Deaven; P., Zhang; R. S., Chaganti; R., Dalla Favera; J. J., Russo
Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
2011 Fabbri, G; Rasi, S; Rossi, D; Trifonov, V; Khiabanian, H; Ma, J; Grunn, A; Fangazio, M; Capello, D; Monti, S; Cresta, S; Gargiulo, E; Forconi, F; Guarini, A; Arcaini, L; Paulli, M; Laurenti, L; Larocca, Lm; Marasca, R; Gattei, V; Oscieri, D; Bertoni, F; Mullighan, Cg; Foa’, R; Pasqualucci, Laura; Rabadan, R; Dalla Favera, R; Gaidano, G.
Analysis of the coding genome of diffuse large B cell lymphoma
2011 Pasqualucci, Laura; Trifonov, V; Fabbri, G; Ma, J; Rossi, D; Chiarenza, A; Wells, Va; Grunn, A; Messina, M; Elliot, O; Chan, J; Bhagat, G; Chadburn, A; Gaidano, G; Mullighan, Cg; Rabadan, R; Dalla Favera, R.
Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice.
1996 A., Terenzi; A., Bolognesi; Pasqualucci, Laura; L., Flenghi; S., Pileri; H., Stein; M., Kadin; B., Bigerna; L., Polito; P. L., Tazzari; Martelli, Massimo Fabrizio; F., Stirpe; Falini, Brunangelo
Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma.
1995 Pasqualucci, Laura; M., Wasik; B. A., Teicher; L., Flenghi; A., Bolognesi; F., Stirpe; L., Polito; Falini, Brunangelo; M. E., Kadin
B-cell receptor signaling derailed in lymphomas.
2010 U., Klein; Pasqualucci, Laura
BCL-6 in aids-related lymphomas: pathogenetic and histogenetic implications.
1998 G., Gaidano; D., Capello; A., Gloghini; C., Pastore; A., Migliazza; S., Quattrone; F., Savinelli; D., Buonaiuto; A. M., Cilia; T., Perin; Pasqualucci, Laura; V., Canzonieri; G., Saglio; R., Dalla Favera; A., Carbone
BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia.
2000 Pasqualucci, Laura; A., Neri; L., Baldini; R., Dalla Favera; A., Migliazza
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci.
1998 Pasqualucci, Laura; A., Migliazza; N., Fracchiolla; C., William; A., Neri; L., Baldini; R. S., Chaganti; U., Klein; R., Küppers; K., Rajewsky; R., Dalla Favera
Bcl-6 protein expression in normal and neoplastic lymphoid tissues.
1997 Falini, Brunangelo; M., Fizzotti; S., Pileri; A., Liso; Pasqualucci, Laura; L., Flenghi
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. | 2007 | Saito, M.; Gao, J.; Basso, K.; Kitagawa, Y.; Smith, P. M.; Bhagat, G.; Pernis, A.; Pasqualucci, Laura; Dalla Favera, R. | |
| Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma. | 2003 | G., Gaidano; Pasqualucci, Laura; D., Capello; E., Berra; C., Deambrogi; D., Rossi; L. M., Larocca; A., Gloghini; A., Carbone; R., Dalla Favera | |
| Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders. | 2004 | M., Cerri; D., Capello; G., Muti; A., Rambaldi; M., Paulli; A., Gloghini; E., Berra; C., Deambrogi; D., Rossi; S., Franceschetti; A., Conconi; E., Morra; Pasqualucci, Laura; A., Carbone; G., Gaidano | |
| Aberrant somatic hypermutation in primary mediastinal large B-cell lymphoma. | 2005 | Rossi, D; Cerri, M; Capello, D; Deambrogi, C; Berra, E; Franceschetti, S; Alabiso, O; Gloghini, A; Paulli, M; Carbone, A; Pileri, Sa; Pasqualucci, Laura; Gaidano, G. | |
| Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma. | 2006 | D., Rossi; E., Berra; M., Cerri; C., Deambrogi; C., Barbieri; S., Franceschetti; M., Lunghi; A., Conconi; M., Paulli; A., Matolcsy; Pasqualucci, Laura; D., Capello; G., Gaidano | |
| Aberrant somatic hypermutation in tumor cells of nodular lymphocyte-predominant and classical Hodgkin's lymphoma. | 2006 | Liso, A.; Capello, D.; Marafiori, T.; Tiacci, E.; Cerri, M.; Distler, V.; Paulli, M.; Carbone, A.; Delson, G.; Campo, E.; Pileri, S.; Pasqualucci, Laura; Gaidano, G.; Falini, B. | |
| AID is required for germinal center-derived lymphomagenesis. | 2008 | Pasqualucci, Laura; Bhagat, G.; Jankovic, M.; Compagno, M.; Smith, P.; Muramatsu, M.; Honjo, T.; Morse H. C., Iii; Nussenzweig, M.; Dalla Favera, R. | |
| Alterations of BIRC3 and multiple other NF-kB pathway genes in splenic marginal zone lymphoma | 2011 | Rossi, D; Deaglio, S; Dominguez Sola, D; Rasi, S; Vaisitti, T; Agostinelli, C; Spina, V; Bruscaggin, A; Monti, S; Cerri, M; Cresta, S; Fangazio, M; Arcaini, L; Lucioni, M; Marasca, R; Thieblemont, C; Capello, D; Facchetti, F; Kwee, I; Pileri, Sa; Foà, R; Bertoni, F; Dalla Favera, R; Pasqualucci, Laura; Gaidano, G. | |
| An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities | 2021 | Flümann, Ruth; Rehkämper, Tim; Nieper, Pascal; Pfeiffer, Pauline; Holzem, Alessandra; Klein, Sebastian; Bhatia, Sanil; Kochanek, Moritz; Kisis, Ilmars; Pelzer, Benedikt W; Ahlert, Heinz; Hauer, Julia; da Palma Guerreiro, Alexandra; Ryan, Jeremy A; Reimann, Maurice; Riabinska, Arina; Wiederstein, Janica; Krüger, Marcus; Deckert, Martina; Altmüller, Janine; Klatt, Andreas R; Frenzel, Lukas P; Pasqualucci, Laura; Béguelin, Wendy; Melnick, Ari M; Sander, Sandrine; Montesinos-Rongen, Manuel; Brunn, Anna; Lohneis, Philipp; Büttner, Reinhard; Kashkar, Hamid; Borkhardt, Arndt; Letai, Anthony; Persigehl, Thorsten; Peifer, Martin; Schmitt, Clemens A; Reinhardt, Hans Christian; Knittel, Gero | |
| An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression | 2015 | Zhang, Baochun; Calado, Dinis Pedro; Wang, Zhe; Fröhler, Sebastian; Köchert, Karl; Qian, Yu; Koralov, Sergei B; Schmidt Supprian, Marc; Sasaki, Yoshiteru; Unitt, Christine; Rodig, Scott; Chen, Wei; Dalla Favera, Riccardo; Alt, Frederick W; Pasqualucci, Laura; Rajewsky, Klaus | |
| Analysis of a 69-kb contiguous genomic sequence at a putative tumor suppressor gene locus on human chromosome 6q27. | 1998 | X. Y., Qu; R. S., Hauptschein; A., Rzhetsky; L., Scotto; M. C., Chien; X., Ye; F., Frigeri; P. H., Rao; Pasqualucci, Laura; B., Gamberi; L. L., Deaven; P., Zhang; R. S., Chaganti; R., Dalla Favera; J. J., Russo | |
| Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation | 2011 | Fabbri, G; Rasi, S; Rossi, D; Trifonov, V; Khiabanian, H; Ma, J; Grunn, A; Fangazio, M; Capello, D; Monti, S; Cresta, S; Gargiulo, E; Forconi, F; Guarini, A; Arcaini, L; Paulli, M; Laurenti, L; Larocca, Lm; Marasca, R; Gattei, V; Oscieri, D; Bertoni, F; Mullighan, Cg; Foa’, R; Pasqualucci, Laura; Rabadan, R; Dalla Favera, R; Gaidano, G. | |
| Analysis of the coding genome of diffuse large B cell lymphoma | 2011 | Pasqualucci, Laura; Trifonov, V; Fabbri, G; Ma, J; Rossi, D; Chiarenza, A; Wells, Va; Grunn, A; Messina, M; Elliot, O; Chan, J; Bhagat, G; Chadburn, A; Gaidano, G; Mullighan, Cg; Rabadan, R; Dalla Favera, R. | |
| Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice. | 1996 | A., Terenzi; A., Bolognesi; Pasqualucci, Laura; L., Flenghi; S., Pileri; H., Stein; M., Kadin; B., Bigerna; L., Polito; P. L., Tazzari; Martelli, Massimo Fabrizio; F., Stirpe; Falini, Brunangelo | |
| Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma. | 1995 | Pasqualucci, Laura; M., Wasik; B. A., Teicher; L., Flenghi; A., Bolognesi; F., Stirpe; L., Polito; Falini, Brunangelo; M. E., Kadin | |
| B-cell receptor signaling derailed in lymphomas. | 2010 | U., Klein; Pasqualucci, Laura | |
| BCL-6 in aids-related lymphomas: pathogenetic and histogenetic implications. | 1998 | G., Gaidano; D., Capello; A., Gloghini; C., Pastore; A., Migliazza; S., Quattrone; F., Savinelli; D., Buonaiuto; A. M., Cilia; T., Perin; Pasqualucci, Laura; V., Canzonieri; G., Saglio; R., Dalla Favera; A., Carbone | |
| BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia. | 2000 | Pasqualucci, Laura; A., Neri; L., Baldini; R., Dalla Favera; A., Migliazza | |
| BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci. | 1998 | Pasqualucci, Laura; A., Migliazza; N., Fracchiolla; C., William; A., Neri; L., Baldini; R. S., Chaganti; U., Klein; R., Küppers; K., Rajewsky; R., Dalla Favera | |
| Bcl-6 protein expression in normal and neoplastic lymphoid tissues. | 1997 | Falini, Brunangelo; M., Fizzotti; S., Pileri; A., Liso; Pasqualucci, Laura; L., Flenghi |