D'AMORE, CLAUDIO
D'AMORE, CLAUDIO
DIPARTIMENTO DI MEDICINA (attivo dal 01/01/2014 al 31/10/2020)
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity.
2012 De Marino, S; Ummarino, R; D'Auria, Mv; Chini, Mg; Bifulco, G; D'Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, S; Fiorucci, Stefano; Zampella, A.
a Farnesoid-X-Receptor (FXR)-Glucocorticoid Receptor (GR) Cascade Regulates Intestinal Innate Immunity in Response to FXR Activation
2012 Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Zampella, A; Distrutti, Eleonora; Fiorucci, Stefano
A Novel Source of Intestinal Damage: The HIV Protease Inhibitor Ritonavir Worsens Damage Caused by COX Inhibitors
2013 Mencarelli, A; Renga, B; Cipriani, S; D'Amore, C; Francisci, D; Baldelli, F; Distrutti, E; Donini, A; Fiorucci, S
Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists.
2014 Hodnik, Ž; Peterlin Mašič, L; Tomašić, T; Smodiš, D; D'Amore, Claudio; Fiorucci, Stefano; Kikelj, D.
Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.
2013 Di Leva, Fs; Festa, C; D'Amore, Claudio; De Marino, S; Renga, Barbara; D'Auria, Mv; Novellino, E; Limongelli, V; Zampella, A; Fiorucci, Stefano
CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination.
2013 Mencarelli, Andrea; Graziosi, L; Renga, Barbara; Cipriani, Sabrina; D'Amore, Claudio; Francisci, Daniela; Bruno, A; Baldelli, Franco; Donini, Annibale; Fiorucci, Stefano
Conicasterol E, a Small Heterodimer PartnerSparing Farnesoid X Receptor Modulator Endowed with a Pregnane X ReceptorAgonistic Activity, from the Marine Sponge Theonella swinhoei
2012 Sepe, V; Ummarino, R; D'Auria, Mv; Chini, Mg; Bifulco, G; Renga, Barbara; D'Amore, Claudio; Debitus, C; Fiorucci, Stefano; Zampella, A.
Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors.
2014 D'Amore, Claudio; Di Leva, Fs; Sepe, V; Renga, Barbara; Del Gaudio, C; D'Auria, Mv; Zampella, A; Fiorucci, Stefano; Limongelli, V.
Diethylstilbestrol-scaffold-based pregnane X receptor modulators
2015 Hodnik, Ž; Tomašič, T; Smodiš, D; D'Amore, Claudio; Mašič, Lp; Fiorucci, Stefano; Kikelj, D.
Discovery of sulfated sterols from marine invertebrates as a new class of marine naturalantagonists of farnesoid-X-receptor.
2011 Sepe, V; Bifulco, G; Renga, Barbara; D'Amore, Claudio; Fiorucci, Stefano; Zampella, A.
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.
2012 Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Cipriani, Sabrina; D'Auria, Mv; Sepe, V; Chini, Mg; Monti, Mc; Bifulco, G; Zampella, A; Fiorucci, Stefano
Dissociation of intestinal and hepatic activities of FXR and LXRα supports metabolic effects of terminal ileum interposition in rodents.
2013 Mencarelli, Andrea; Renga, Barbara; D'Amore, Claudio; Santorelli, C; Graziosi, L; Bruno, A; Monti, Mc; Distrutti, Eleonora; Cipriani, Sabrina; Donini, Annibale; Fiorucci, Stefano
Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice.
2013 Cipriani, Sabrina; Francisci, Daniela; Mencarelli, Andrea; Renga, Barbara; Schiaroli, Elisabetta; D'Amore, Claudio; Baldelli, Franco; Fiorucci, Stefano
Epigenetic modulation by methionine deficiency attenuates the potential for gastric cancer cell dissemination.
2013 Graziosi, Luigina; Mencarelli, Andrea; Renga, Barbara; D'Amore, Claudio; Bruno, A; Santorelli, C; Cavazzoni, Emanuel; Cantarella, Francesco; Rosati, E; Donini, Annibale; Fiorucci, Stefano
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands
2014 Festa, C; Renga, Barbara; D'Amore, Claudio; Sepe, V; Finamore, C; De Marino, S; Carino, A.; Cipriani, Sabrina; Monti, Mc; Zampella, A; Fiorucci, Stefano; Carino, Adriana
Farnesoid X receptor suppresses constitutive androstane receptoractivity at the multidrug resistance protein-4 promoter.
2011 Renga, Barbara; Migliorati, M; Mencarelli, Andrea; Cipriani, Sabrina; D'Amore, Claudio; Distrutti, Eleonora; Fiorucci, Stefano
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.
2013 Renga, Barbara; D'Amore, Claudio; Cipriani, Sabrina; Mencarelli, Andrea; Carino, A; Sepe, V; Zampella, A; Distrutti, Eleonora; Fiorucci, Stefano; Carino, Adriana
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition
2012 Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Cipriani, Sabrina; Baldelli, Franco; A., Zampella; Distrutti, Eleonora; Fiorucci, Stefano
HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes
2012 Renga, Barbara; Francisci, Daniela; D'Amore, Claudio; Schiaroli, Elisabetta; Carino, A.; Baldelli, Franco; Fiorucci, Stefano; Carino, Adriana
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling
2015 Cipriani, Sabrina; Renga, Barbara; D'Amore, Claudio; Simonetti, M; De Tursi, Aa; Carino, Adriana; Monti, Mc; Sepe, V; Zampella, A; Fiorucci, Stefano
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity. | 2012 | De Marino, S; Ummarino, R; D'Auria, Mv; Chini, Mg; Bifulco, G; D'Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, S; Fiorucci, Stefano; Zampella, A. | |
a Farnesoid-X-Receptor (FXR)-Glucocorticoid Receptor (GR) Cascade Regulates Intestinal Innate Immunity in Response to FXR Activation | 2012 | Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Zampella, A; Distrutti, Eleonora; Fiorucci, Stefano | |
A Novel Source of Intestinal Damage: The HIV Protease Inhibitor Ritonavir Worsens Damage Caused by COX Inhibitors | 2013 | Mencarelli, A; Renga, B; Cipriani, S; D'Amore, C; Francisci, D; Baldelli, F; Distrutti, E; Donini, A; Fiorucci, S | |
Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists. | 2014 | Hodnik, Ž; Peterlin Mašič, L; Tomašić, T; Smodiš, D; D'Amore, Claudio; Fiorucci, Stefano; Kikelj, D. | |
Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands. | 2013 | Di Leva, Fs; Festa, C; D'Amore, Claudio; De Marino, S; Renga, Barbara; D'Auria, Mv; Novellino, E; Limongelli, V; Zampella, A; Fiorucci, Stefano | |
CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination. | 2013 | Mencarelli, Andrea; Graziosi, L; Renga, Barbara; Cipriani, Sabrina; D'Amore, Claudio; Francisci, Daniela; Bruno, A; Baldelli, Franco; Donini, Annibale; Fiorucci, Stefano | |
Conicasterol E, a Small Heterodimer PartnerSparing Farnesoid X Receptor Modulator Endowed with a Pregnane X ReceptorAgonistic Activity, from the Marine Sponge Theonella swinhoei | 2012 | Sepe, V; Ummarino, R; D'Auria, Mv; Chini, Mg; Bifulco, G; Renga, Barbara; D'Amore, Claudio; Debitus, C; Fiorucci, Stefano; Zampella, A. | |
Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors. | 2014 | D'Amore, Claudio; Di Leva, Fs; Sepe, V; Renga, Barbara; Del Gaudio, C; D'Auria, Mv; Zampella, A; Fiorucci, Stefano; Limongelli, V. | |
Diethylstilbestrol-scaffold-based pregnane X receptor modulators | 2015 | Hodnik, Ž; Tomašič, T; Smodiš, D; D'Amore, Claudio; Mašič, Lp; Fiorucci, Stefano; Kikelj, D. | |
Discovery of sulfated sterols from marine invertebrates as a new class of marine naturalantagonists of farnesoid-X-receptor. | 2011 | Sepe, V; Bifulco, G; Renga, Barbara; D'Amore, Claudio; Fiorucci, Stefano; Zampella, A. | |
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis. | 2012 | Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Cipriani, Sabrina; D'Auria, Mv; Sepe, V; Chini, Mg; Monti, Mc; Bifulco, G; Zampella, A; Fiorucci, Stefano | |
Dissociation of intestinal and hepatic activities of FXR and LXRα supports metabolic effects of terminal ileum interposition in rodents. | 2013 | Mencarelli, Andrea; Renga, Barbara; D'Amore, Claudio; Santorelli, C; Graziosi, L; Bruno, A; Monti, Mc; Distrutti, Eleonora; Cipriani, Sabrina; Donini, Annibale; Fiorucci, Stefano | |
Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice. | 2013 | Cipriani, Sabrina; Francisci, Daniela; Mencarelli, Andrea; Renga, Barbara; Schiaroli, Elisabetta; D'Amore, Claudio; Baldelli, Franco; Fiorucci, Stefano | |
Epigenetic modulation by methionine deficiency attenuates the potential for gastric cancer cell dissemination. | 2013 | Graziosi, Luigina; Mencarelli, Andrea; Renga, Barbara; D'Amore, Claudio; Bruno, A; Santorelli, C; Cavazzoni, Emanuel; Cantarella, Francesco; Rosati, E; Donini, Annibale; Fiorucci, Stefano | |
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands | 2014 | Festa, C; Renga, Barbara; D'Amore, Claudio; Sepe, V; Finamore, C; De Marino, S; Carino, A.; Cipriani, Sabrina; Monti, Mc; Zampella, A; Fiorucci, Stefano; Carino, Adriana | |
Farnesoid X receptor suppresses constitutive androstane receptoractivity at the multidrug resistance protein-4 promoter. | 2011 | Renga, Barbara; Migliorati, M; Mencarelli, Andrea; Cipriani, Sabrina; D'Amore, Claudio; Distrutti, Eleonora; Fiorucci, Stefano | |
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents. | 2013 | Renga, Barbara; D'Amore, Claudio; Cipriani, Sabrina; Mencarelli, Andrea; Carino, A; Sepe, V; Zampella, A; Distrutti, Eleonora; Fiorucci, Stefano; Carino, Adriana | |
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition | 2012 | Renga, Barbara; Mencarelli, Andrea; D'Amore, Claudio; Cipriani, Sabrina; Baldelli, Franco; A., Zampella; Distrutti, Eleonora; Fiorucci, Stefano | |
HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes | 2012 | Renga, Barbara; Francisci, Daniela; D'Amore, Claudio; Schiaroli, Elisabetta; Carino, A.; Baldelli, Franco; Fiorucci, Stefano; Carino, Adriana | |
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling | 2015 | Cipriani, Sabrina; Renga, Barbara; D'Amore, Claudio; Simonetti, M; De Tursi, Aa; Carino, Adriana; Monti, Mc; Sepe, V; Zampella, A; Fiorucci, Stefano |