DATTI, Alessandro
DATTI, Alessandro
Dipartimento di Scienze Agrarie, Alimentari ed Ambientali
"BIOCHIMICA" Campbell Farrell
2006 Altieri, F.; Balduini, C.; Bevilacqua, M.; Canton, M.; Datti, Alessandro; Di Lisa, F.; Faraonio, R.; Ferraro, A.; Kaludercic, N.; Landi, L.; Orlacchio, Aldo; Russo, G.; Santamaria, R.; Stoppini, M.; Urbanelli, L.; Zambrano, N.; Zanetti, G.
A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2
2006 Mao, X.; Stewart, A. K.; Hurren, R.; Datti, Alessandro; Shi, C. X.; Zhu, Y. X.; Lee, K.; Tiedemann, R.; Eberhard, Y.; Corey, S. J.; Wrana, J.; Schimmer, A. D.
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin
2007 Mao, X.; Stewart, A.; Hurren, R.; Datti, Alessandro; Zhu, X.; Zhu, Y.; Shi, C.; Lee, K.; Tiedemann, R.; Eberhard, Y.; Trudel, S.; Liang, S.; Corey, S.; Gillis, L.; Barber, D.; Wrana, J.; Ezzat, S.; Schimmer, A.
A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis
2007 Mawji, I. A.; Simpson, C. D.; Gronda, M.; Williams, M. A.; Hurren, R.; Henderson, C. J.; Datti, Alessandro; Wrana, J. L.; Schimmer, A. D.
A coupled assay for UDP-GlcNAc:Galβ1-3GalNAc-R β1,6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc)
1992 Datti, Alessandro; Orlacchio, Aldo; Siminovitch, K. A.; Dennis, J. W.
A drug discovery platform to identify compounds that inhibit EGFR triple mutants
2020 Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis; Wybenga-Groot, Leanne E; Weiss, Konstantin; Rai, Ankit; Radulovich, Nikolina; Drecun, Luka; Vučković, Nika; Vučetić, Adriana; Wong, Victoria; Thériault, Brigitte; Pham, Nhu-An; Park, Jin H; Datti, Alessandro; Wang, Jenny; Pathmanathan, Shivanthy; Aboualizadeh, Farzaneh; Lyakisheva, Anna; Yao, Zhong; Wang, Yuhui; Joseph, Babu; Aman, Ahmed; Moran, Michael F; Prakesch, Michael; Poda, Gennady; Marcellus, Richard; Uehling, David; Samaržija, Miroslav; Jakopović, Marko; Tsao, Ming-Sound; Shepherd, Frances A; Sacher, Adrian; Leighl, Natasha; Akhmanova, Anna; Al-Awar, Rima; Zerial, Marino; Stagljar, Igor
A Fluorescent Assay for the Determination of UDP-GlcNAc: Galβ1,3GalNAc-R (GlcNAc to GalNAc) β-1,6 N-Acetylglucosaminyltransferase Activity
1995 Palmerini, Carlo Alberto; Datti, Alessandro; Alunni, S.; Vanderelst, I. E.; Orlacchio, Aldo
A high throughput seeking myeloma therapeutics identifies glucocorticoids as inhibitors of c-Maf-dependent transactivation of cyclin D2
2005 Mao, X.; Stewart, A. K.; Datti, Alessandro; Schimmer, A. D.
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization
2008 Xu, G. W.; Mawji, I. A.; Macrae, C. J.; Koch, C. A.; Datti, Alessandro; Wrana, J. L.; Dennis, J. W.; Schimmer, A. D.
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors
2000 Datti, Alessandro; Donovan, R. S.; Korczak, B.; Dennis, J. W.
A HOMOGENEOUS CELL-BASED ASSAY TO IDENTIFY N-LINKED CARBOHYDRATE PROCESSING INHIBITORS
2000 Datti, Alessandro; Donovan, R. S.; Korczak, B.; Dennis, J. W.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
2013 Vizeacoumar, Fj; Arnold, R; Vizeacoumar, Fs; Chandrashekhar, M; Buzina, A; Young, Jtf; Kwan, Jhm; Sayad, A; Mero, P; Lawo, S; Tanaka, H; Brown, Kr; Baryshnikova, A; Mak, Ab; Fedyshyn, Y; Wang, Y; Brito, Gc; Kasimer, D; Makhnevych, T; Ketela, T; Datti, Alessandro; Babu, M; Emili, A; Pelletier, L; Wrana, J; Wainberg, Z; Kim, Pm; Rottapel, R; O'Brien, Ca; Andrews, B; Boone, C; Moffat, J.
A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma
2008 Mao, X.; Wood, T. W.; Wang, X.; St Germain, J.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D.
A repurposing strategy identifies novel synergistic inhibitors of plasmodium falciparum heat shock protein 90
2010 Shahinas, D.; Liang, M.; Datti, Alessandro; Pillai, D. R.
A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia
2009 Mao, X.; Wood, T. E.; Hurren, R.; Tong, J.; Wang, X.; Spagnuolo, P. A.; Maclean, N.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D.
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside
2012 Mcdermott, S. P.; Eppert, K.; Notta, F.; Isaac, M.; Datti, Alessandro; Al awar, R.; Wrana, J.; Minden, M. D.; Dick, J. E.
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway
2011 Mao, X.; Cao, B.; Wood, T. E.; Hurren, R.; Tong, J.; Wang, X.; Wang, W.; Li, J.; Jin, Y.; Sun, W.; Spagnuolo, P. A.; Maclean, N.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D.
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research
1999 Donovan, R. S.; Datti, Alessandro; Baek, M. G.; Wu, Q.; Sas, I. J.; Korczak, B.; Berger, E. G.; Roy, R.; Dennis, J. W.
A SOLID-PHASE GLYCOSYLTRANSFERASE ASSAY FOR HIGH-THROUGHPUT SCREENING IN DRUG DISCOVERY RESEARCH
2000 Donovan, R. S.; Datti, Alessandro; Baek, M. G.; Wu, Q.; Sas, I. J.; Korczak, B.; Berger, E. G.; Roy, R.; Dennis, J. W.
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening
2014 Jouhyun, Jeon; Satra, Nim; Joan, Teyra; Datti, Alessandro; Jeffrey L., Wrana; Sachdev S., Sidhu; Jason, Moffat; Philip M., Kim
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
"BIOCHIMICA" Campbell Farrell | 2006 | Altieri, F.; Balduini, C.; Bevilacqua, M.; Canton, M.; Datti, Alessandro; Di Lisa, F.; Faraonio, R.; Ferraro, A.; Kaludercic, N.; Landi, L.; Orlacchio, Aldo; Russo, G.; Santamaria, R.; Stoppini, M.; Urbanelli, L.; Zambrano, N.; Zanetti, G. | |
A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2 | 2006 | Mao, X.; Stewart, A. K.; Hurren, R.; Datti, Alessandro; Shi, C. X.; Zhu, Y. X.; Lee, K.; Tiedemann, R.; Eberhard, Y.; Corey, S. J.; Wrana, J.; Schimmer, A. D. | |
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin | 2007 | Mao, X.; Stewart, A.; Hurren, R.; Datti, Alessandro; Zhu, X.; Zhu, Y.; Shi, C.; Lee, K.; Tiedemann, R.; Eberhard, Y.; Trudel, S.; Liang, S.; Corey, S.; Gillis, L.; Barber, D.; Wrana, J.; Ezzat, S.; Schimmer, A. | |
A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis | 2007 | Mawji, I. A.; Simpson, C. D.; Gronda, M.; Williams, M. A.; Hurren, R.; Henderson, C. J.; Datti, Alessandro; Wrana, J. L.; Schimmer, A. D. | |
A coupled assay for UDP-GlcNAc:Galβ1-3GalNAc-R β1,6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) | 1992 | Datti, Alessandro; Orlacchio, Aldo; Siminovitch, K. A.; Dennis, J. W. | |
A drug discovery platform to identify compounds that inhibit EGFR triple mutants | 2020 | Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis; Wybenga-Groot, Leanne E; Weiss, Konstantin; Rai, Ankit; Radulovich, Nikolina; Drecun, Luka; Vučković, Nika; Vučetić, Adriana; Wong, Victoria; Thériault, Brigitte; Pham, Nhu-An; Park, Jin H; Datti, Alessandro; Wang, Jenny; Pathmanathan, Shivanthy; Aboualizadeh, Farzaneh; Lyakisheva, Anna; Yao, Zhong; Wang, Yuhui; Joseph, Babu; Aman, Ahmed; Moran, Michael F; Prakesch, Michael; Poda, Gennady; Marcellus, Richard; Uehling, David; Samaržija, Miroslav; Jakopović, Marko; Tsao, Ming-Sound; Shepherd, Frances A; Sacher, Adrian; Leighl, Natasha; Akhmanova, Anna; Al-Awar, Rima; Zerial, Marino; Stagljar, Igor | |
A Fluorescent Assay for the Determination of UDP-GlcNAc: Galβ1,3GalNAc-R (GlcNAc to GalNAc) β-1,6 N-Acetylglucosaminyltransferase Activity | 1995 | Palmerini, Carlo Alberto; Datti, Alessandro; Alunni, S.; Vanderelst, I. E.; Orlacchio, Aldo | |
A high throughput seeking myeloma therapeutics identifies glucocorticoids as inhibitors of c-Maf-dependent transactivation of cyclin D2 | 2005 | Mao, X.; Stewart, A. K.; Datti, Alessandro; Schimmer, A. D. | |
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization | 2008 | Xu, G. W.; Mawji, I. A.; Macrae, C. J.; Koch, C. A.; Datti, Alessandro; Wrana, J. L.; Dennis, J. W.; Schimmer, A. D. | |
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors | 2000 | Datti, Alessandro; Donovan, R. S.; Korczak, B.; Dennis, J. W. | |
A HOMOGENEOUS CELL-BASED ASSAY TO IDENTIFY N-LINKED CARBOHYDRATE PROCESSING INHIBITORS | 2000 | Datti, Alessandro; Donovan, R. S.; Korczak, B.; Dennis, J. W. | |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities | 2013 | Vizeacoumar, Fj; Arnold, R; Vizeacoumar, Fs; Chandrashekhar, M; Buzina, A; Young, Jtf; Kwan, Jhm; Sayad, A; Mero, P; Lawo, S; Tanaka, H; Brown, Kr; Baryshnikova, A; Mak, Ab; Fedyshyn, Y; Wang, Y; Brito, Gc; Kasimer, D; Makhnevych, T; Ketela, T; Datti, Alessandro; Babu, M; Emili, A; Pelletier, L; Wrana, J; Wainberg, Z; Kim, Pm; Rottapel, R; O'Brien, Ca; Andrews, B; Boone, C; Moffat, J. | |
A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma | 2008 | Mao, X.; Wood, T. W.; Wang, X.; St Germain, J.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D. | |
A repurposing strategy identifies novel synergistic inhibitors of plasmodium falciparum heat shock protein 90 | 2010 | Shahinas, D.; Liang, M.; Datti, Alessandro; Pillai, D. R. | |
A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia | 2009 | Mao, X.; Wood, T. E.; Hurren, R.; Tong, J.; Wang, X.; Spagnuolo, P. A.; Maclean, N.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D. | |
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside | 2012 | Mcdermott, S. P.; Eppert, K.; Notta, F.; Isaac, M.; Datti, Alessandro; Al awar, R.; Wrana, J.; Minden, M. D.; Dick, J. E. | |
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway | 2011 | Mao, X.; Cao, B.; Wood, T. E.; Hurren, R.; Tong, J.; Wang, X.; Wang, W.; Li, J.; Jin, Y.; Sun, W.; Spagnuolo, P. A.; Maclean, N.; Moran, M. F.; Datti, Alessandro; Wrana, J.; Batey, R. A.; Schimmer, A. D. | |
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research | 1999 | Donovan, R. S.; Datti, Alessandro; Baek, M. G.; Wu, Q.; Sas, I. J.; Korczak, B.; Berger, E. G.; Roy, R.; Dennis, J. W. | |
A SOLID-PHASE GLYCOSYLTRANSFERASE ASSAY FOR HIGH-THROUGHPUT SCREENING IN DRUG DISCOVERY RESEARCH | 2000 | Donovan, R. S.; Datti, Alessandro; Baek, M. G.; Wu, Q.; Sas, I. J.; Korczak, B.; Berger, E. G.; Roy, R.; Dennis, J. W. | |
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening | 2014 | Jouhyun, Jeon; Satra, Nim; Joan, Teyra; Datti, Alessandro; Jeffrey L., Wrana; Sachdev S., Sidhu; Jason, Moffat; Philip M., Kim |