COSTANTINO, Gabriele
COSTANTINO, Gabriele
DIPARTIMENTO DI SCIENZE FARMACEUTICHE
"*-Diazocarbonyl Chemistry - Target Driven Applications"
1998 Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Mattoli, L.; Natalini, Benedetto
(2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties
2001 Pellicciari, Roberto; Marinozzi, Maura; Costantino, Gabriele; Natalini, Benedetto; Moroni, F.; Pellegrini Giampietro, D.
1,4 Benzothiazine and 1,4 benzoxazine imidazole derivatives with antifungal activity: a docking study
2002 Macchiarulo, Antonio; Costantino, Gabriele; Fringuelli, D.; Vecchiarelli, Anna; Schiaffella, Fausto; Fringuelli, Renata
1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS
1995 Pellicciari, Roberto; R., Luneia; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto; P., Jakobsen; A., Kanstrup; G., Lombardi; F., Moroni; C., Thomsen
Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D
1998 Marinozzi, Maura; Costantino, Gabriele; D. E., Pellegrini Giampietro; Pellicciari, Roberto
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors
1996 Marinozzi, Maura; Natalini, Benedetto; Costantino, Gabriele; P., Tijskens; C., Thomsen; Pellicciari, Roberto
Autocorrelation as a tool for a congruent description of molecu¬les in 3D-QSAR studies
1993 Clementi, Sergio; Cruciani, Gabriele; D., Riganelli; Valigi, Roberta; Costantino, Gabriele; Baroni, Massimo; S., Wold
Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure Activity Relationship of a Series of Body and Side Chain Modified Analogs of Chenodeoxycholic Acid
2004 Pellicciari, Roberto; Costantino, Gabriele; Camaioni, Emidio; Sadeghpour, B. M.; Entrena Guadix, A.; Willson, T.; Fiorucci, Stefano; Clerici, C.; Gioiello, Antimo
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR)
2003 Costantino, Gabriele; Macchiarulo, Antonio; Entrena Guadix, A.; Camaioni, Emidio; Pellicciari, Roberto
Binding modes of noncompetitive AMPA Antagonists: A computational approach
2003 De Luca, L.; Macchiarulo, Antonio; Costantino, Gabriele; Barreca, MARIA LETIZIA; Gitto, R.; Chimirri, A.; Pellicciari, Roberto
Bulky 1,4-benzoxazine derivatives with antifungal activity
2009 Fringuelli, Renata; Giacche', Nicola; Milanese, Lara; Cenci, Elio; Macchiarulo, Antonio; Vecchiarelli, Anna; Costantino, Gabriele; Schiaffella, Fausto
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives
2001 Natalini, Benedetto; Marinozzi, Maura; Costantino, Gabriele; Pellicciari, Roberto; Capodiferro, V.; Mattoli, L.
Conformational requirements for interaction of L-glutamate with the metabotropic EAA receptor
1993 Costantino, Gabriele; Natalini, Benedetto; Pellicciari, Roberto
Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase
1993 Costantino, Gabriele; Natalini, Benedetto; Pellicciari, Roberto; F., Moroni; G., Lombardi
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents
2003 Camaioni, Emidio; Costantino, Gabriele; Macchiarulo, Antonio; Marinozzi, Maura; F., Moroni; Pellicciari, Roberto
Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents
2006 Camaioni, Emidio; P., Sabbatini; Costantino, Gabriele; D., Bellocchi; A., Chiarugi; F., Moroni; A., Wood; Pellicciari, Roberto
Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors
2001 Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Amori, L.; Flor, P.; Gasparini, F.; Kuhn, R.; Urwyler, S.
Design, Synthesis, and Microbiolgical Evaluation of New Candida albicans CYP51 Inhibitors
2005 Schiaffella, Fausto; Macchiarulo, Antonio; Milanese, Lara; Vecchiarelli, Anna; Costantino, Gabriele; Pietrella, Donatella; Fringuelli, Renata
Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes
1997 Pellicciari, Roberto; Annibali, D; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
2021 Biagioli, Michele; Marchianò, Silvia; Roselli, Rosalinda; Di Giorgio, Cristina; Bellini, Rachele; Bordoni, Martina; Gidari, Anna; Sabbatini, Samuele; Francisci, Daniela; Fiorillo, Bianca; Catalanotti, Bruno; Distrutti, Eleonora; Carino, Adriana; Zampella, Angela; Costantino, Gabriele; Fiorucci, Stefano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| "*-Diazocarbonyl Chemistry - Target Driven Applications" | 1998 | Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Mattoli, L.; Natalini, Benedetto | |
| (2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties | 2001 | Pellicciari, Roberto; Marinozzi, Maura; Costantino, Gabriele; Natalini, Benedetto; Moroni, F.; Pellegrini Giampietro, D. | |
| 1,4 Benzothiazine and 1,4 benzoxazine imidazole derivatives with antifungal activity: a docking study | 2002 | Macchiarulo, Antonio; Costantino, Gabriele; Fringuelli, D.; Vecchiarelli, Anna; Schiaffella, Fausto; Fringuelli, Renata | |
| 1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS | 1995 | Pellicciari, Roberto; R., Luneia; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto; P., Jakobsen; A., Kanstrup; G., Lombardi; F., Moroni; C., Thomsen | |
| Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D | 1998 | Marinozzi, Maura; Costantino, Gabriele; D. E., Pellegrini Giampietro; Pellicciari, Roberto | |
| Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors | 1996 | Marinozzi, Maura; Natalini, Benedetto; Costantino, Gabriele; P., Tijskens; C., Thomsen; Pellicciari, Roberto | |
| Autocorrelation as a tool for a congruent description of molecu¬les in 3D-QSAR studies | 1993 | Clementi, Sergio; Cruciani, Gabriele; D., Riganelli; Valigi, Roberta; Costantino, Gabriele; Baroni, Massimo; S., Wold | |
| Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure Activity Relationship of a Series of Body and Side Chain Modified Analogs of Chenodeoxycholic Acid | 2004 | Pellicciari, Roberto; Costantino, Gabriele; Camaioni, Emidio; Sadeghpour, B. M.; Entrena Guadix, A.; Willson, T.; Fiorucci, Stefano; Clerici, C.; Gioiello, Antimo | |
| Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) | 2003 | Costantino, Gabriele; Macchiarulo, Antonio; Entrena Guadix, A.; Camaioni, Emidio; Pellicciari, Roberto | |
| Binding modes of noncompetitive AMPA Antagonists: A computational approach | 2003 | De Luca, L.; Macchiarulo, Antonio; Costantino, Gabriele; Barreca, MARIA LETIZIA; Gitto, R.; Chimirri, A.; Pellicciari, Roberto | |
| Bulky 1,4-benzoxazine derivatives with antifungal activity | 2009 | Fringuelli, Renata; Giacche', Nicola; Milanese, Lara; Cenci, Elio; Macchiarulo, Antonio; Vecchiarelli, Anna; Costantino, Gabriele; Schiaffella, Fausto | |
| Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives | 2001 | Natalini, Benedetto; Marinozzi, Maura; Costantino, Gabriele; Pellicciari, Roberto; Capodiferro, V.; Mattoli, L. | |
| Conformational requirements for interaction of L-glutamate with the metabotropic EAA receptor | 1993 | Costantino, Gabriele; Natalini, Benedetto; Pellicciari, Roberto | |
| Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase | 1993 | Costantino, Gabriele; Natalini, Benedetto; Pellicciari, Roberto; F., Moroni; G., Lombardi | |
| Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents | 2003 | Camaioni, Emidio; Costantino, Gabriele; Macchiarulo, Antonio; Marinozzi, Maura; F., Moroni; Pellicciari, Roberto | |
| Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents | 2006 | Camaioni, Emidio; P., Sabbatini; Costantino, Gabriele; D., Bellocchi; A., Chiarugi; F., Moroni; A., Wood; Pellicciari, Roberto | |
| Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors | 2001 | Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Amori, L.; Flor, P.; Gasparini, F.; Kuhn, R.; Urwyler, S. | |
| Design, Synthesis, and Microbiolgical Evaluation of New Candida albicans CYP51 Inhibitors | 2005 | Schiaffella, Fausto; Macchiarulo, Antonio; Milanese, Lara; Vecchiarelli, Anna; Costantino, Gabriele; Pietrella, Donatella; Fringuelli, Renata | |
| Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes | 1997 | Pellicciari, Roberto; Annibali, D; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto | |
| Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction | 2021 | Biagioli, Michele; Marchianò, Silvia; Roselli, Rosalinda; Di Giorgio, Cristina; Bellini, Rachele; Bordoni, Martina; Gidari, Anna; Sabbatini, Samuele; Francisci, Daniela; Fiorillo, Bianca; Catalanotti, Bruno; Distrutti, Eleonora; Carino, Adriana; Zampella, Angela; Costantino, Gabriele; Fiorucci, Stefano |