The enantioselective synthesis of (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl) glycine (PCCG-4, 3), a potent and selective mGluR2 antagonist is described.
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors
MARINOZZI, Maura;NATALINI, Benedetto;COSTANTINO, Gabriele;PELLICCIARI, Roberto
1996
Abstract
The enantioselective synthesis of (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl) glycine (PCCG-4, 3), a potent and selective mGluR2 antagonist is described.File in questo prodotto:
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