IRIS - Res&Arch Institutional Research Information System - Research & Archive

Orașul în literatura românească de secol XIX

Two Decades of NPM1-Mutated Acute Myeloid Leukemia: From Molecular Insights to Clinical Decision-Making

: NPM1-mutated acute myeloid leukemia (AML) represents one of the most frequent and biologically distinct AML entities, characterized by the aberrant cytoplasmic localization of the NPM1 mutant protein. The recent advances in molecular biology and translational research have progressively redefined the clinical management of this disease. This narrative review summarizes the evolution of NPM1-mutated AML over the last two decades, focusing on the transition from immunohistochemical observatio...

Hydropower, expertise, and attempted Italian economic imperialism in Dalmatia. Nitrogen fixation in ‘the Norway of the Mediterranean’ (1902–1945)

This article analyzes the rise and decline of the electrochemical industry in Dalmatia between 1902 and 1945, with particular attention paid to production of the nitrogen fertilizer calcium cyanamide, made from calcium carbide. Central to the discussion is the Sufid company – which made Dalmatia the world’s second largest producer of calcium cyanamide after Scandinavia – that projected Italian capitalism beyond national borders by linking industrial, financial, and diplomatic interests. ...

First nuclear ultraheavy dark matter search in argon time projection chambers with the DarkSide-50 experiment

We report on the first search for nuclear ultraheavy dark matter (UHDM) in a dual-phase liquid argon time projection chamber using the DarkSide-50 experiment. Unlike conventional weakly interacting massive particles, a nuclear UHDM model may be composed of many dark nucleons and scatter numerous times while passing through the detector. Accounting for energy loss through the Earth's overburden, we apply selection criteria optimized for multiscatter event topologies using the 532-day low-radia...