Physicochemical properties of nanosized polymeric drug carrier systems

This chapter is to explore the utilization of biodegradable nanostructured polymers and their associated physicochemical properties in pharmaceutical application. The main hub of the pharma industry is involved in the development of innovative biodegradable and biocompatible polymers that have targeting ability and a predictable release profile of an incorporated active pharmaceutical ingredient or therapeutic agents. Moreover, the pharmaceutical and biological efficiency of the nano-drug delivery system varies with the inherent properties of the polymer. The foremost, important physicochemical properties of biodegradable polymers include molecular weight, hydrophobicity, surface charge, and size. Nevertheless, these properties can be manipulated to modify the kinetics of the delivery system by selecting an optimum polymer (based on physicochemical properties) for a specific purpose.