(2R,3S,4S)-α-(carboxycyclopropyl)glycine of the formula (1) and salts thereof are disclosed. The compound (1) exhibits most potent depolarizing activities among the known NMDA agonists and will be a useful tool to investigate various neuronal functions related to the excitatory amino acid receptors.
3,4-Cyclopropyl Glutamates as Conformationally Restricted Agonists of the NMDA Receptor
PELLICCIARI, Roberto;NATALINI, Benedetto;MARINOZZI, Maura;
1988
Abstract
(2R,3S,4S)-α-(carboxycyclopropyl)glycine of the formula (1) and salts thereof are disclosed. The compound (1) exhibits most potent depolarizing activities among the known NMDA agonists and will be a useful tool to investigate various neuronal functions related to the excitatory amino acid receptors.File in questo prodotto:
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