Sfoglia per Autore
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors
2014 Manfroni, Giuseppe; Cannalire, Rolando; Barreca, MARIA LETIZIA; Kaushik Basu, Neerja; Leyssen, Pieter; Winquist, Johan; Iraci, Nunzio; Manvar, Dinesh; Paeshuyse, Jan; Guhamazumder, Rupa; Basu, Amartya; Sabatini, Stefano; Tabarrini, Oriana; Danielson U., Helena; Neyts, Johan; Cecchetti, Violetta
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors
2014 Manfroni, Giuseppe; Manvar, Dinesh; Barreca, MARIA LETIZIA; Kaushik Basu, Neerja; Leyssen, Pieter; Paeshuyse, Jan; Cannalire, Rolando; Iraci, Nunzio; Basu, Amartya; Chudaev, Maxim; Zamperini, Claudio; Dreassi, Elena; Sabatini, Stefano; Tabarrini, Oriana; Neyts, Johan; Cecchetti, Violetta
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization
2015 Astolfi, Andrea; Barreca, MARIA LETIZIA; Iraci, Nunzio; Cannalire, Rolando; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta
Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives
2015 Franci, G; Manfroni, Giuseppe; Cannalire, Rolando; Felicetti, Tommaso; Tabarrini, Oriana; Salvato, A; Barreca, MARIA LETIZIA; Altucci, L; Cecchetti, Violetta
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors
2015 Sabatini, Stefano; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Bauer, Silke M; Gargaro, Marco; Cannalire, Rolando; Astolfi, Andrea; Brea, Jose; Vacca, Carmine; Pirro, Matteo; Massari, Serena; Tabarrini, Oriana; Loza, Maria Isabel; Fallarino, Francesca; Laufer, Stefan A; Cecchetti, Violetta
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium
2015 Machado, Diana; Cannalire, Rolando; Santos Costa, Sofia; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
2016 Tarantino, Delia; Cannalire, Rolando; Mastrangelo, Eloise; Croci, Romina; Querat, Gilles; Barreca, MARIA LETIZIA; Bolognesi, Martino; Manfroni, Giuseppe; Cecchetti, Violetta; Milani, Mario
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates
2016 Cannalire, Rolando; Barreca, MARIA LETIZIA; Manfroni, Giuseppe; Cecchetti, Violetta
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues
2017 Felicetti, Tommaso; Cannalire, Rolando; Burali, MARIA SOLE; Massari, Serena; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Tabarrini, Oriana; Schindler, Bryan D; Sabatini, Stefano; Kaatz, Glenn W; Cecchetti, Violetta
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli
2017 Machado, Diana; Fernandes, Laura; Costa, Sofia S.; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Couto, Isabel; Sabatini, Stefano; Viveiros, Miguel
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium
2017 Cannalire, Rolando; Machado, Diana; Felicetti, Tommaso; Santos Costa, Sofia; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano; Cecchetti, Violetta
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones
2018 Cannalire, Rolando; Tiecco, Matteo; Cecchetti, Violetta; Germani, Raimondo; Manfroni, Giuseppe
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position
2018 Felicetti, T.; Cannalire, R.; Nizi, M. G.; Tabarrini, O.; Massari, S.; Barreca, M. L.; Manfroni, G.; Schindler, B. D.; Cecchetti, V.; Kaatz, G. W.; Sabatini, S.
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction
2018 Felicetti, Tommaso; Cannalire, Rolando; Pietrella, Donatella; Latacz, Gniewomir; Lubelska, Annamaria; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Massari, Serena; Tabarrini, Oriana; Kieć-Kononowicz, Katarzyna; Schindler, Bryan D.; Kaatz, Glenn W.; Cecchetti, Violetta; Sabatini, Stefano
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase
2018 Cannalire, Rolando; Tarantino, Delia; Astolfi, Andrea; Barreca, MARIA LETIZIA; Sabatini, Stefano; Massari, Serena; Tabarrini, Oriana; Milani, Mario; Querat, Gilles; Mastrangelo, Eloise; Manfroni, Giuseppe; Cecchetti, Violetta
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions
2019 Cannalire, R.; Tarantino, D.; Piorkowski, G.; Carletti, T.; Massari, S.; Felicetti, T.; Barreca, M. L.; Sabatini, S.; Tabarrini, O.; Marcello, A.; Milani, M.; Cecchetti, V.; Mastrangelo, E.; Manfroni, G.; Querat, G.
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation
2019 Astolfi, A.; Kudolo, M.; Brea, J.; Manni, G.; Manfroni, G.; Palazzotti, D.; Sabatini, S.; Cecchetti, F.; Felicetti, T.; Cannalire, R.; Massari, S.; Tabarrini, O.; Loza, M. I.; Fallarino, F.; Cecchetti, V.; Laufer, S. A.; Barreca, M. L.
Evolution of HCV NS4B Inhibitors
2019 Manfroni, G.; Cannalire, R.
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders.
2019 Desantis, J.; Massari, S.; Sosic, A.; Manfroni, G.; Cannalire, R.; Felicetti, T.; Pannecouque, P.; Gatto, B.; Tabarrini, O.
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants
2019 Felicetti, T.; Machado, D.; Cannalire, R.; Astolfi, A.; Massari, S.; Tabarrini, O.; Manfroni, G.; Barreca, M. L.; Cecchetti, V.; Viveiros, M.; Sabatini, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors | 2014 | Manfroni, Giuseppe; Cannalire, Rolando; Barreca, MARIA LETIZIA; Kaushik Basu, Neerja; Leyssen, Pieter; Winquist, Johan; Iraci, Nunzio; Manvar, Dinesh; Paeshuyse, Jan; Guhamazumder, Rupa; Basu, Amartya; Sabatini, Stefano; Tabarrini, Oriana; Danielson U., Helena; Neyts, Johan; Cecchetti, Violetta | |
| New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors | 2014 | Manfroni, Giuseppe; Manvar, Dinesh; Barreca, MARIA LETIZIA; Kaushik Basu, Neerja; Leyssen, Pieter; Paeshuyse, Jan; Cannalire, Rolando; Iraci, Nunzio; Basu, Amartya; Chudaev, Maxim; Zamperini, Claudio; Dreassi, Elena; Sabatini, Stefano; Tabarrini, Oriana; Neyts, Johan; Cecchetti, Violetta | |
| Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization | 2015 | Astolfi, Andrea; Barreca, MARIA LETIZIA; Iraci, Nunzio; Cannalire, Rolando; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta | |
| Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives | 2015 | Franci, G; Manfroni, Giuseppe; Cannalire, Rolando; Felicetti, Tommaso; Tabarrini, Oriana; Salvato, A; Barreca, MARIA LETIZIA; Altucci, L; Cecchetti, Violetta | |
| The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors | 2015 | Sabatini, Stefano; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Bauer, Silke M; Gargaro, Marco; Cannalire, Rolando; Astolfi, Andrea; Brea, Jose; Vacca, Carmine; Pirro, Matteo; Massari, Serena; Tabarrini, Oriana; Loza, Maria Isabel; Fallarino, Francesca; Laufer, Stefan A; Cecchetti, Violetta | |
| Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium | 2015 | Machado, Diana; Cannalire, Rolando; Santos Costa, Sofia; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano | |
| Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor | 2016 | Tarantino, Delia; Cannalire, Rolando; Mastrangelo, Eloise; Croci, Romina; Querat, Gilles; Barreca, MARIA LETIZIA; Bolognesi, Martino; Manfroni, Giuseppe; Cecchetti, Violetta; Milani, Mario | |
| A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates | 2016 | Cannalire, Rolando; Barreca, MARIA LETIZIA; Manfroni, Giuseppe; Cecchetti, Violetta | |
| Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues | 2017 | Felicetti, Tommaso; Cannalire, Rolando; Burali, MARIA SOLE; Massari, Serena; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Tabarrini, Oriana; Schindler, Bryan D; Sabatini, Stefano; Kaatz, Glenn W; Cecchetti, Violetta | |
| Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli | 2017 | Machado, Diana; Fernandes, Laura; Costa, Sofia S.; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Couto, Isabel; Sabatini, Stefano; Viveiros, Miguel | |
| Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium | 2017 | Cannalire, Rolando; Machado, Diana; Felicetti, Tommaso; Santos Costa, Sofia; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano; Cecchetti, Violetta | |
| Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones | 2018 | Cannalire, Rolando; Tiecco, Matteo; Cecchetti, Violetta; Germani, Raimondo; Manfroni, Giuseppe | |
| Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position | 2018 | Felicetti, T.; Cannalire, R.; Nizi, M. G.; Tabarrini, O.; Massari, S.; Barreca, M. L.; Manfroni, G.; Schindler, B. D.; Cecchetti, V.; Kaatz, G. W.; Sabatini, S. | |
| 2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction | 2018 | Felicetti, Tommaso; Cannalire, Rolando; Pietrella, Donatella; Latacz, Gniewomir; Lubelska, Annamaria; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Massari, Serena; Tabarrini, Oriana; Kieć-Kononowicz, Katarzyna; Schindler, Bryan D.; Kaatz, Glenn W.; Cecchetti, Violetta; Sabatini, Stefano | |
| Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase | 2018 | Cannalire, Rolando; Tarantino, Delia; Astolfi, Andrea; Barreca, MARIA LETIZIA; Sabatini, Stefano; Massari, Serena; Tabarrini, Oriana; Milani, Mario; Querat, Gilles; Mastrangelo, Eloise; Manfroni, Giuseppe; Cecchetti, Violetta | |
| Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions | 2019 | Cannalire, R.; Tarantino, D.; Piorkowski, G.; Carletti, T.; Massari, S.; Felicetti, T.; Barreca, M. L.; Sabatini, S.; Tabarrini, O.; Marcello, A.; Milani, M.; Cecchetti, V.; Mastrangelo, E.; Manfroni, G.; Querat, G. | |
| Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation | 2019 | Astolfi, A.; Kudolo, M.; Brea, J.; Manni, G.; Manfroni, G.; Palazzotti, D.; Sabatini, S.; Cecchetti, F.; Felicetti, T.; Cannalire, R.; Massari, S.; Tabarrini, O.; Loza, M. I.; Fallarino, F.; Cecchetti, V.; Laufer, S. A.; Barreca, M. L. | |
| Evolution of HCV NS4B Inhibitors | 2019 | Manfroni, G.; Cannalire, R. | |
| Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. | 2019 | Desantis, J.; Massari, S.; Sosic, A.; Manfroni, G.; Cannalire, R.; Felicetti, T.; Pannecouque, P.; Gatto, B.; Tabarrini, O. | |
| Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants | 2019 | Felicetti, T.; Machado, D.; Cannalire, R.; Astolfi, A.; Massari, S.; Tabarrini, O.; Manfroni, G.; Barreca, M. L.; Cecchetti, V.; Viveiros, M.; Sabatini, S. |
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