IRACI, NUNZIO
IRACI, NUNZIO
DIPARTIMENTO DI SCIENZE FARMACEUTICHE
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT
2007 Patrizia, Logoteta; Iraci, Nunzio; LAURA DE, Luca; Stefania, Ferro; Barreca, MARIA LETIZIA; ERIK DE, Clercq; Alba, Chimirri; ANNA MARIA, Monforte
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT
2007 Logoteta, P; Iraci, Nunzio; DE LUCA, L; Ferro, S; Barreca, MARIA LETIZIA; DE CLERCQ, E; Chimirri, A.
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities
2013 Sancineto, Luca; Iraci, Nunzio; Massari, Serena; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta; Tabarrini, Oriana
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists
2006 Gitto, R; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; Ferro, S; Arstad, E; Chimirri, A.
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors
2015 Astolfi, Andrea; Iraci, Nunzio; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Cecchetti, Violetta
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.
2012 Shytaj, Il; Norelli, S; Chirullo, B; Della Corte, A; Collins, M; Yalley Ogunro, J; Greenhouse, J; Iraci, Nunzio; Acosta, Ep; Barreca, MARIA LETIZIA; Lewis, Mg; Savarino, A.
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors
2006 DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Chimirri, A.
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors
2008 LAURA DE, Luca; Barreca, MARIA LETIZIA; Stefania, Ferro; Iraci, Nunzio; Zeger, Debyser; MYRIAM WITVROUW AND ALBA, Chimirri
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.
2008 DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Michiels, M; Christ, F; Debyser, Z; Witvrouw, M; Chimirri, A.
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy
2009 DE LUCA, L; Ferro, S; Agnello, S; Gitto, R; Monforte, A. M.; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z; Chimirri, A.
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study.
2014 Barreca, MARIA LETIZIA; Iraci, Nunzio; Manfroni, Giuseppe; Gaetani, Rosy; Guercini, Chiara; Sabatini, Stefano; Tabarrini, Oriana; Cecchetti, Violetta
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development
2011 Barreca, MARIA LETIZIA; Iraci, Nunzio; Manfroni, Giuseppe; Cecchetti, Violetta
beta-CYCLODEXTRIN HINDERS PLGA PLASTICIZATION DURING MICROPARTICLE MANUFACTURING
2015 Albertini, Barbara; Iraci, Nunzio; Schoubben, Aurelie Marie Madeleine; Giovagnoli, Stefano; Ricci, Maurizio; Blasi, Paolo; Rossi, Carlo
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase
2006 Barreca, MARIA LETIZIA; De Luca, L.; Iraci, Nunzio; Chimirri, A.
Computational Strategies for Discovering novel HIV-1 RT Inhibitors
2005 Iraci, Nunzio; Barreca, MARIA LETIZIA; De Luca, L.; Rao, A.; Monforte, A. M.; Chimirri, A.
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity
2013 Sancineto, Luca; Iraci, Nunzio; Massari, Serena; Vanessa, Attanasio; Gianmarco, Corazza; Barreca, MARIA LETIZIA; Sabatini, Stefano; Manfroni, Giuseppe; Nilla Roberta, Avanzi; Cecchetti, Violetta; Christophe, Pannecouque; Alessandro, Marcello; Tabarrini, Oriana
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity
2013 Iraci, Nunzio; Sancineto, Luca; Barreca, MARIA LETIZIA; Massari, Serena; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta; Tabarrini, Oriana
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES
2015 Iraci, Nunzio; Stincardini, Claudia; Barreca, MARIA LETIZIA; Biasini, Emiliano
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity
2015 Sancineto, Luca; Mariotti, Alice; Bagnoli, Luana; Marini, Francesca; Desantis, Jenny; Iraci, Nunzio; Santi, Claudio; Pannecouque, Christophe; Tabarrini, Oriana
Design and synthesis of NR2B Subtype-Selective Antagonist
2005 Gitto, R.; De Luca, L.; Barreca, MARIA LETIZIA; Iraci, Nunzio; Iannì, P.; Chimirri, A.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT | 2007 | Patrizia, Logoteta; Iraci, Nunzio; LAURA DE, Luca; Stefania, Ferro; Barreca, MARIA LETIZIA; ERIK DE, Clercq; Alba, Chimirri; ANNA MARIA, Monforte | |
| 1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT | 2007 | Logoteta, P; Iraci, Nunzio; DE LUCA, L; Ferro, S; Barreca, MARIA LETIZIA; DE CLERCQ, E; Chimirri, A. | |
| 2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities | 2013 | Sancineto, Luca; Iraci, Nunzio; Massari, Serena; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta; Tabarrini, Oriana | |
| 3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists | 2006 | Gitto, R; DE LUCA, L; Barreca, MARIA LETIZIA; Iraci, Nunzio; Ferro, S; Arstad, E; Chimirri, A. | |
| A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors | 2015 | Astolfi, Andrea; Iraci, Nunzio; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Cecchetti, Violetta | |
| A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. | 2012 | Shytaj, Il; Norelli, S; Chirullo, B; Della Corte, A; Collins, M; Yalley Ogunro, J; Greenhouse, J; Iraci, Nunzio; Acosta, Ep; Barreca, MARIA LETIZIA; Lewis, Mg; Savarino, A. | |
| A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors | 2006 | DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Chimirri, A. | |
| A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors | 2008 | LAURA DE, Luca; Barreca, MARIA LETIZIA; Stefania, Ferro; Iraci, Nunzio; Zeger, Debyser; MYRIAM WITVROUW AND ALBA, Chimirri | |
| A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series. | 2008 | DE LUCA, L; Barreca, MARIA LETIZIA; Ferro, S; Iraci, Nunzio; Michiels, M; Christ, F; Debyser, Z; Witvrouw, M; Chimirri, A. | |
| A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy | 2009 | DE LUCA, L; Ferro, S; Agnello, S; Gitto, R; Monforte, A. M.; Iraci, Nunzio; Barreca, MARIA LETIZIA; Debyser, Z; Chimirri, A. | |
| Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. | 2014 | Barreca, MARIA LETIZIA; Iraci, Nunzio; Manfroni, Giuseppe; Gaetani, Rosy; Guercini, Chiara; Sabatini, Stefano; Tabarrini, Oriana; Cecchetti, Violetta | |
| Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development | 2011 | Barreca, MARIA LETIZIA; Iraci, Nunzio; Manfroni, Giuseppe; Cecchetti, Violetta | |
| beta-CYCLODEXTRIN HINDERS PLGA PLASTICIZATION DURING MICROPARTICLE MANUFACTURING | 2015 | Albertini, Barbara; Iraci, Nunzio; Schoubben, Aurelie Marie Madeleine; Giovagnoli, Stefano; Ricci, Maurizio; Blasi, Paolo; Rossi, Carlo | |
| Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase | 2006 | Barreca, MARIA LETIZIA; De Luca, L.; Iraci, Nunzio; Chimirri, A. | |
| Computational Strategies for Discovering novel HIV-1 RT Inhibitors | 2005 | Iraci, Nunzio; Barreca, MARIA LETIZIA; De Luca, L.; Rao, A.; Monforte, A. M.; Chimirri, A. | |
| Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity | 2013 | Sancineto, Luca; Iraci, Nunzio; Massari, Serena; Vanessa, Attanasio; Gianmarco, Corazza; Barreca, MARIA LETIZIA; Sabatini, Stefano; Manfroni, Giuseppe; Nilla Roberta, Avanzi; Cecchetti, Violetta; Christophe, Pannecouque; Alessandro, Marcello; Tabarrini, Oriana | |
| Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity | 2013 | Iraci, Nunzio; Sancineto, Luca; Barreca, MARIA LETIZIA; Massari, Serena; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta; Tabarrini, Oriana | |
| DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES | 2015 | Iraci, Nunzio; Stincardini, Claudia; Barreca, MARIA LETIZIA; Biasini, Emiliano | |
| Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity | 2015 | Sancineto, Luca; Mariotti, Alice; Bagnoli, Luana; Marini, Francesca; Desantis, Jenny; Iraci, Nunzio; Santi, Claudio; Pannecouque, Christophe; Tabarrini, Oriana | |
| Design and synthesis of NR2B Subtype-Selective Antagonist | 2005 | Gitto, R.; De Luca, L.; Barreca, MARIA LETIZIA; Iraci, Nunzio; Iannì, P.; Chimirri, A. |