DE FALCO, FILOMENA
DE FALCO, FILOMENA
DIPARTIMENTO DI MEDICINA E CHIRURGIA
A DYSREGULATED, DRUGGABLE PP2A/AKT/GSK3 beta AXIS SUSTAINS NOTCH1 SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS
2020 De Falco, F; Rosati, E; Del Papa, B; Baldoni, S; Di Ianni, M; Screpanti, I; Sportoletti, P
A NOVEL MECHANISM FOR NOTCH1 ACTIVATIONIN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS: INVOLVEMENT OF NOTCH1 ENDOSOMAL TRAFFICKING AND ALTERATIONS IN RAB PROTEINS
2020 Del Papa, B; De Falco, F; Baldoni, S; Dorillo, E; Rompietti, C; Adamo, F; Scialdone, Ar; Guarente, V; Di Ianni, M; Mondani, E; Cecchini, D; Cantelmi, Mg; Ostini, Ri; Rosati, E; Sportoletti, P
A pro-inflammatory environment in bone marrow of Treg transplanted patients matches with graft-versus-leukemia effect
2023 Guardalupi, Francesco; Sorrentino, Carlo; Corradi, Giulia; Giancola, Raffaella; Baldoni, Stefano; Ulbar, Francesca; Fabi, Bianca; Andres Ejarque, Rosa; Timms, Jessica; Restuccia, Francesco; Santarone, Stella; Accorsi, Patrizia; Sportoletti, Paolo; De Falco, Filomena; Rosati, Emanuela; Carotti, Alessandra; Falzetti, Franca; Velardi, Andrea; Martelli, Massimo Fabrizio; Kordasti, Shahram; Pierini, Antonio; Ruggeri, Loredana; Di Ianni, Mauro
Antibody Response to the SARS-CoV-2 Vaccine and COVID-19 Vulnerability during the Omicron Pandemic in Patients with CLL: Two-Year Follow-Up of a Multicenter Study
2023 Mauro, Francesca R; Giannarelli, Diana; Galluzzo, Clementina M; Visentin, Andrea; Frustaci, Anna M; Sportoletti, Paolo; Vitale, Candida; Reda, Gianluigi; Gentile, Massimo; Levato, Luciano; Murru, Roberta; Armiento, Daniele; Molinari, Maria C; Proietti, Giulia; Pepe, Sara; De Falco, Filomena; Mattiello, Veronica; Barabino, Luca; Amici, Roberta; Coscia, Marta; Tedeschi, Alessandra; Girmenia, Corrado; Trentin, Livio; Baroncelli, Silvia
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia
2018 Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P.
BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo
2016 Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P
Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia
2021 Guarente, V.; Martino, G.; Dorillo, E.; De Falco, F.; Rompietti, C.; Sorcini, D.; Brogna, M.; Cardinali, V.; Ascani, S.; Marra, A.; Sportoletti, P.
Cocaine Addiction Treatment and Home Remedies: Use of the Scopolamine Transdermal Patch
2014 Gambelunghe, Cristiana; Bacci, Mauro; Aroni, Kyriaki; DE FALCO, Filomena; Ayroldi, Emira Maria
Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.
2015 DE FALCO, Filomena; Sabatini, Rita; Falzetti, Franca; Di Ianni, M; Sportoletti, Paolo; Baldoni, S; DEL PAPA, Beatrice; Screpanti, I; Marconi, Pierfrancesco; Rosati, Emanuela
CURCUMIN EXHIBITS IN VITRO AND IN VIVO ANTI-LEUKEMIC ACTIVITY INTERFERING WITH THE NOTCH1 PATHWAY AND INDUCING ENDOPLASMIC RETICULUM STRESS IN CHRONIC LYMPHOCYTIC LEUKEMIA
2020 SILVA BARCELOS, ESTEVAO CARLOS; Rompietti, C; Del Papa, B; De Falco, F; Baldoni, S; Dorillo, E; Adamo, Fm; Sorcini, D; Stella, A; Sartori, S; Scialdone, Ar; Guarente, V; Mondani, E; Cecchini, D; Cantelmi, Mg; Rosati, E; Sportoletti, P
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia
2019 DEL PAPA, Beatrice; Baldoni, Stefano; Dorillo, Erica; DE FALCO, Filomena; Rompietti, Chiara; Cecchini, Debora; Cantelmi, Maria Grazia; Sorcini, Daniele; Nogarotto, Manuel; Adamo, FRANCESCO MARIA; Mezzasoma, Federica; Carlos Silva Barcelos, Estevão; Albi, Elisa; Iacucci Ostini, Roberta; Di Tommaso, Ambra; Marra, Andrea; Montanaro, Guido; Martelli, Maria Paola; Falzetti, Franca; DI IANNI, Mauro; Rosati, Emanuela; Sportoletti, Paolo
FLT3-targeted therapy restores GATA1 pathway function in NPM1/FLT3-ITD mutated acute myeloid leukaemia
2023 Sorcini, D; Stella, A; Scialdone, A; Sartori, S; Marra, A; Rossi, R; De Falco, F; Adamo, F M; Dorillo, E; Geraci, C; Arcaleni, R; Rompietti, C; Esposito, A; Moretti, L; Mameli, M G; Martelli, M P; Falini, B; Sportoletti, P
GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL
2022 De Falco, Filomena; Rompietti, Chiara; Sorcini, Daniele; Esposito, Angela; Scialdone, Annarita; Baldoni, Stefano; Del Papa, Beatrice; Adamo, Francesco Maria; Silva Barcelos, Estevão Carlos; Dorillo, Erica; Stella, Arianna; Di Ianni, Mauro; Screpanti, Isabella; Sportoletti, Paolo; Rosati, Emanuela
IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation.
2018 De Falco, F; Del Papa, B; Baldoni, S; Sabatini, R; Falzetti, F; Di Ianni, M; Martelli, Mp; Mezzasoma, F; Pelullo, M; Marconi, P; Sportoletti, P; Screpanti, I; Rosati, E.
Immune correlates of protection by vaccine against SARS-CoV-2 in patients with chronic lymphocytic leukaemia
2023 Sorcini, D.; De Falco, F.; Gargaro, M.; Bozza, S.; Guarente, V.; Cardinali, V.; Stella, A.; Adamo, F. M.; Silva Barcelos, E. C.; Rompietti, C.; Dorillo, E.; Geraci, C.; Esposito, A.; Arcaleni, R.; Capoccia, S.; Mameli, M. G.; Graziani, A.; Moretti, L.; Cipiciani, A.; Riccardi, C.; Mencacci, A.; Fallarino, F.; Rosati, E.; Sportoletti, P.
IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY
2015 Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F
NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications
2021 Sportoletti, Paolo; DE FALCO, Filomena; Del Papa, Beatrice; Baldoni, Stefano; Guarente, Valerio; Marra, Andrea; Dorillo, Erica; Rompietti, Chiara; Adamo, FRANCESCO MARIA; Ruggeri, Loredana; Di Ianni, Mauro; Rosati, Emanuela
Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL
2015 DE FALCO, Filomena; Sabatini, Rita; DEL PAPA, Beatrice; Falzetti, Franca; DI IANNI, Mauro; Sportoletti, Paolo; Baldoni, Stefano; Screpanti, Isabella; Marconi, Pierfrancesco; Rosati, Emanuela
NOTCH-1 ACTIVATION AND SUBCLONAL MUTATION NEGATIVELY IMPACT ON CHRONIC LYMPHOCYTIC LEUKEMIA OUTCOMES
2020 Baldoni, S; Del Papa, B; Dorillo, E; De Falco, F; Rompietti, C; Adamo, Fm; Cecchini, D; Mondani, E; Zei, T; Fabi, B; Cantelmi, Mg; Guarente, V; Di Ianni, M; Rosati, E; Sportoletti, P
NOTCH1 Aberrations in Chronic Lymphocytic Leukemia.
2018 Rosati, E; Baldoni, S; De Falco, F; Del Papa, B; Dorillo, E; Rompietti, C; Albi, E; Falzetti, F; Di Ianni, M; Sportoletti, P
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A DYSREGULATED, DRUGGABLE PP2A/AKT/GSK3 beta AXIS SUSTAINS NOTCH1 SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS | 2020 | De Falco, F; Rosati, E; Del Papa, B; Baldoni, S; Di Ianni, M; Screpanti, I; Sportoletti, P | |
| A NOVEL MECHANISM FOR NOTCH1 ACTIVATIONIN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS: INVOLVEMENT OF NOTCH1 ENDOSOMAL TRAFFICKING AND ALTERATIONS IN RAB PROTEINS | 2020 | Del Papa, B; De Falco, F; Baldoni, S; Dorillo, E; Rompietti, C; Adamo, F; Scialdone, Ar; Guarente, V; Di Ianni, M; Mondani, E; Cecchini, D; Cantelmi, Mg; Ostini, Ri; Rosati, E; Sportoletti, P | |
| A pro-inflammatory environment in bone marrow of Treg transplanted patients matches with graft-versus-leukemia effect | 2023 | Guardalupi, Francesco; Sorrentino, Carlo; Corradi, Giulia; Giancola, Raffaella; Baldoni, Stefano; Ulbar, Francesca; Fabi, Bianca; Andres Ejarque, Rosa; Timms, Jessica; Restuccia, Francesco; Santarone, Stella; Accorsi, Patrizia; Sportoletti, Paolo; De Falco, Filomena; Rosati, Emanuela; Carotti, Alessandra; Falzetti, Franca; Velardi, Andrea; Martelli, Massimo Fabrizio; Kordasti, Shahram; Pierini, Antonio; Ruggeri, Loredana; Di Ianni, Mauro | |
| Antibody Response to the SARS-CoV-2 Vaccine and COVID-19 Vulnerability during the Omicron Pandemic in Patients with CLL: Two-Year Follow-Up of a Multicenter Study | 2023 | Mauro, Francesca R; Giannarelli, Diana; Galluzzo, Clementina M; Visentin, Andrea; Frustaci, Anna M; Sportoletti, Paolo; Vitale, Candida; Reda, Gianluigi; Gentile, Massimo; Levato, Luciano; Murru, Roberta; Armiento, Daniele; Molinari, Maria C; Proietti, Giulia; Pepe, Sara; De Falco, Filomena; Mattiello, Veronica; Barabino, Luca; Amici, Roberta; Coscia, Marta; Tedeschi, Alessandra; Girmenia, Corrado; Trentin, Livio; Baroncelli, Silvia | |
| Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia | 2018 | Baldoni, S; Del Papa, B; Dorillo, E; Aureli, P; De Falco, F; Rompietti, C; Sorcini, D; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; Rosati, E; Alexe, G; Roti, G; Stegmaier, K; Di Ianni, M; Falzetti, F; Sportoletti, P. | |
| BEPRIDIL IS A POTENT NOTCH1 INHIBITOR AND EFFICIENTLY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL) CELLS in vitro AND in vivo | 2016 | Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Zei, T; Iacucci, R; Cecchini, D; Di Tommaso, A; De Falco, F; Plebani, S; Roti, G; Stegmaier, K; Rosati, E; Di Ianni, M; Falzetti, F; Sportoletti, P | |
| Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia | 2021 | Guarente, V.; Martino, G.; Dorillo, E.; De Falco, F.; Rompietti, C.; Sorcini, D.; Brogna, M.; Cardinali, V.; Ascani, S.; Marra, A.; Sportoletti, P. | |
| Cocaine Addiction Treatment and Home Remedies: Use of the Scopolamine Transdermal Patch | 2014 | Gambelunghe, Cristiana; Bacci, Mauro; Aroni, Kyriaki; DE FALCO, Filomena; Ayroldi, Emira Maria | |
| Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation. | 2015 | DE FALCO, Filomena; Sabatini, Rita; Falzetti, Franca; Di Ianni, M; Sportoletti, Paolo; Baldoni, S; DEL PAPA, Beatrice; Screpanti, I; Marconi, Pierfrancesco; Rosati, Emanuela | |
| CURCUMIN EXHIBITS IN VITRO AND IN VIVO ANTI-LEUKEMIC ACTIVITY INTERFERING WITH THE NOTCH1 PATHWAY AND INDUCING ENDOPLASMIC RETICULUM STRESS IN CHRONIC LYMPHOCYTIC LEUKEMIA | 2020 | SILVA BARCELOS, ESTEVAO CARLOS; Rompietti, C; Del Papa, B; De Falco, F; Baldoni, S; Dorillo, E; Adamo, Fm; Sorcini, D; Stella, A; Sartori, S; Scialdone, Ar; Guarente, V; Mondani, E; Cecchini, D; Cantelmi, Mg; Rosati, E; Sportoletti, P | |
| Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia | 2019 | DEL PAPA, Beatrice; Baldoni, Stefano; Dorillo, Erica; DE FALCO, Filomena; Rompietti, Chiara; Cecchini, Debora; Cantelmi, Maria Grazia; Sorcini, Daniele; Nogarotto, Manuel; Adamo, FRANCESCO MARIA; Mezzasoma, Federica; Carlos Silva Barcelos, Estevão; Albi, Elisa; Iacucci Ostini, Roberta; Di Tommaso, Ambra; Marra, Andrea; Montanaro, Guido; Martelli, Maria Paola; Falzetti, Franca; DI IANNI, Mauro; Rosati, Emanuela; Sportoletti, Paolo | |
| FLT3-targeted therapy restores GATA1 pathway function in NPM1/FLT3-ITD mutated acute myeloid leukaemia | 2023 | Sorcini, D; Stella, A; Scialdone, A; Sartori, S; Marra, A; Rossi, R; De Falco, F; Adamo, F M; Dorillo, E; Geraci, C; Arcaleni, R; Rompietti, C; Esposito, A; Moretti, L; Mameli, M G; Martelli, M P; Falini, B; Sportoletti, P | |
| GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL | 2022 | De Falco, Filomena; Rompietti, Chiara; Sorcini, Daniele; Esposito, Angela; Scialdone, Annarita; Baldoni, Stefano; Del Papa, Beatrice; Adamo, Francesco Maria; Silva Barcelos, Estevão Carlos; Dorillo, Erica; Stella, Arianna; Di Ianni, Mauro; Screpanti, Isabella; Sportoletti, Paolo; Rosati, Emanuela | |
| IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation. | 2018 | De Falco, F; Del Papa, B; Baldoni, S; Sabatini, R; Falzetti, F; Di Ianni, M; Martelli, Mp; Mezzasoma, F; Pelullo, M; Marconi, P; Sportoletti, P; Screpanti, I; Rosati, E. | |
| Immune correlates of protection by vaccine against SARS-CoV-2 in patients with chronic lymphocytic leukaemia | 2023 | Sorcini, D.; De Falco, F.; Gargaro, M.; Bozza, S.; Guarente, V.; Cardinali, V.; Stella, A.; Adamo, F. M.; Silva Barcelos, E. C.; Rompietti, C.; Dorillo, E.; Geraci, C.; Esposito, A.; Arcaleni, R.; Capoccia, S.; Mameli, M. G.; Graziani, A.; Moretti, L.; Cipiciani, A.; Riccardi, C.; Mencacci, A.; Fallarino, F.; Rosati, E.; Sportoletti, P. | |
| IN VITRO AND IN VIVO ANTILEUKEMIC ACTIVITY OF BEPRIDIL IN CHRONIC LYMPHOCYTIC LEUKEMIA IS ASSOCIATED WITH INHIBITION OF THE NOTCH1 PATHWAY | 2015 | Sportoletti, P; Baldoni, S; Del Papa, B; Aureli, P; Dorillo, E; Varasano, E; Cecchini, D; Zei, T; Di Tommaso, A; De Falco, F; Plebani, S; Amico, V; Roti, G; Stegmaier, K; Rosati, E; Falini, B; Di Ianni, M; Falzetti, F | |
| NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications | 2021 | Sportoletti, Paolo; DE FALCO, Filomena; Del Papa, Beatrice; Baldoni, Stefano; Guarente, Valerio; Marra, Andrea; Dorillo, Erica; Rompietti, Chiara; Adamo, FRANCESCO MARIA; Ruggeri, Loredana; Di Ianni, Mauro; Rosati, Emanuela | |
| Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL | 2015 | DE FALCO, Filomena; Sabatini, Rita; DEL PAPA, Beatrice; Falzetti, Franca; DI IANNI, Mauro; Sportoletti, Paolo; Baldoni, Stefano; Screpanti, Isabella; Marconi, Pierfrancesco; Rosati, Emanuela | |
| NOTCH-1 ACTIVATION AND SUBCLONAL MUTATION NEGATIVELY IMPACT ON CHRONIC LYMPHOCYTIC LEUKEMIA OUTCOMES | 2020 | Baldoni, S; Del Papa, B; Dorillo, E; De Falco, F; Rompietti, C; Adamo, Fm; Cecchini, D; Mondani, E; Zei, T; Fabi, B; Cantelmi, Mg; Guarente, V; Di Ianni, M; Rosati, E; Sportoletti, P | |
| NOTCH1 Aberrations in Chronic Lymphocytic Leukemia. | 2018 | Rosati, E; Baldoni, S; De Falco, F; Del Papa, B; Dorillo, E; Rompietti, C; Albi, E; Falzetti, F; Di Ianni, M; Sportoletti, P |