GROHMANN, Ursula

GROHMANN, Ursula  

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3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine 1-gen-2021 Clement, C. C.; D'Alessandro, A.; Thangaswamy, S.; Chalmers, S.; Furtado, R.; Spada, S.; Mondanelli, G.; Ianni, F.; Gehrke, S.; Gargaro, M.; Manni, G.; Cara, L. C. L.; Runge, P.; Tsai, W. L.; Karaman, S.; Arasa, J.; Fernandez-Rodriguez, R.; Beck, A.; Macchiarulo, A.; Gadina, M.; Halin, C.; Fallarino, F.; Skobe, M.; Veldhoen, M.; Moretti, S.; Formenti, S.; Demaria, S.; Soni, R. K.; Galarini, R.; Sardella, R.; Lauvau, G.; Putterman, C.; Alitalo, K.; Grohmann, U.; Santambrogio, L.
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 1-gen-2018 Pallotta, M; Iacono, A; Albini, E; Orabona, C; Belladonna, M; Bianchi, R; Coletti, A; Greco, F; Macchiarulo, A; Grohmann, U
88P - Relationship between functions and intracellular localization of the immune checkpoint target indoleamine 2, 3-dioxygenase 1 1-gen-2018 Iacono, A; Pompa, A; Marchis, De; Bellucci, M; Grassi, F; Grohmann, U; Pallotta, M
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 1-gen-2003 Grohmann, Ursula; Fallarino, Francesca; Bianchi, Roberta; Orabona, Ciriana; Vacca, Carmine; Fioretti, Maria Cristina; Puccetti, Paolo
A general partnership between AhR and tryptophan catabolic enzymes and its role in endotoxin tolerance 1-gen-2016 Gargaro, Marco; Matino, D; Pirro, Matteo; Puccetti, M; Scalisi, G; Talesa, Vn; Grohmann, Ursula; Macchiarulo, Antonio; Fallarino, Francesca
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 1-gen-2012 Volpi, Claudia; Fallarino, Francesca; Bianchi, Roberta; Orabona, Ciriana; DE LUCA, Antonella; Vacca, Carmine; Romani, Luigina; Gran, B.; Grohmann, Ursula; Puccetti, Paolo; Belladonna, Maria Laura
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 1-gen-2013 C., Mordant; C., Bolea; S., Celanire; I., Royer Urios; Fallarino, Francesca; Orabona, Ciriana; Volpi, Claudia; Grohmann, Ursula
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 1-gen-2020 Mondanelli, Giada; Di Battista, Valeria; Pellanera, Fabrizia; Mammoli, Andrea; Macchiarulo, Antonio; Gargaro, Marco; Mavridou, ELENA ELENI; Matteucci, Caterina; Ruggeri, Loredana; Orabona, Ciriana; Volpi, Claudia; Grohmann, Ursula; Mecucci, Cristina
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 1-gen-2017 Mondanelli, Giada; Bianchi, Roberta; Pallotta, MARIA TERESA; Orabona, Ciriana; Albini, Elisa; Iacono, Alberta; Belladonna, Maria Laura; Vacca, Carmine; Fallarino, Francesca; Macchiarulo, Antonio; Ugel, Stefano; Bronte, Vincenzo; Gevi, Federica; Zolla, Lello; Verhaar, Auke; Peppelenbosch, Maikel; Mazza, Emilia Maria Cristina; Bicciato, Silvio; Laouar, Yasmina; Santambrogio, Laura; Puccetti, Paolo; Volpi, Claudia; Grohmann, Ursula
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815. 1-gen-1996 Belladonna, Maria Laura; Fioretti, Maria Cristina; Bianchi, Roberta; Puccetti, Paolo; Grohmann, Ursula
A TLR9/TRIF PATHWAY INDUCES TOLERANCE VIA TGF-β AND TRYPTOPHAN CATABOLISM IN PLASMACYTOID DENDRITIC CELLS 1-gen-2012 Volpi, Claudia; Gonzalez, Gloria Castellano; Fallarino, Francesca; Grohmann, Ursula; Puccetti, Paolo
A TLR9/TRIF pathway induces tolerance via TGF-beta and tryptophan catabolism in plasmacytoid dendritic cells 1-gen-2012 Volpi, Claudia; Fallarino, Francesca; Grohmann, Ursula; Puccetti, Paolo
A TLR9/TRIF PATHWAY INDUCES TOLERANCE VIA TGF-β AND TRYPTOPHAN CATABOLISM IN PLASMACYTOID DENDRITIC CELLS 1-gen-2013 Volpi, Claudia; Gonzalez, Gloria Castellano; Fallarino, Francesca; Grohmann, Ursula; Puccetti, Paolo
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state 1-gen-1997 Grohmann, Ursula; Bianchi, Roberta; Ayroldi, Emira Maria; Ayroldi, E.; Belladonna, Maria Laura; Surace, D.; Fioretti, Maria Cristina; Puccetti, Paolo
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. 1-gen-1993 Campanile, Franca; A., Giampieri; Grohmann, Ursula; L., Binaglia; Fioretti, Maria Cristina; Puccetti, Paolo
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma 1-gen-2020 Ladomersky, E.; Zhai, L.; Lauing, K. L.; Bell, A.; Xu, J.; Kocherginsky, M.; Zhang, B.; Wu, J. D.; Podojil, J. R.; Platanias, L. C.; Mochizuki, A. Y.; Prins, R. M.; Kumthekar, P.; Raizer, J. J.; Dixit, K.; Lukas, R. V.; Horbinski, C.; Wei, M.; Zhou, C.; Pawelec, G.; Campisi, J.; Grohmann, U.; Prendergast, G. C.; Munn, D. H.; Wainwright, D. A.
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 1-gen-2017 Coletti, Alice; Greco, Francesco Antonio; Dolciami, Daniela; Camaioni, Emidio; Sardella, Roccaldo; Pallotta, Maria Teresa; Volpi, Claudia; Orabona, Ciriana; Grohmann, Ursula; Macchiarulo, Antonio
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 1-gen-2016 Volpi, Claudia; Mondanelli, Giada; Pallotta, MARIA TERESA; Vacca, Carmine; Iacono, Alberta; Gargaro, Marco; Albini, Elisa; Bianchi, Roberta; Belladonna, Maria Laura; Celanire, S; Mordant, C; Heroux, M; Royer Urios, I; Schneider, M; Vitte, Pa; Cacquevel, M; Galibert, L; Poli, Sm; Solari, A; Bicciato, S; Calvitti, Mario; Antognelli, Cinzia; Puccetti, Paolo; Orabona, Ciriana; Fallarino, Francesca; Grohmann, Ursula
Amino acid metabolism as drug target in autoimmune diseases 1-gen-2019 Mondanelli, Giada; Iacono, Alberta; Carvalho, Agostinho; Orabona, Ciriana; Volpi, Claudia; Pallotta, Maria T.; Matino, Davide; Esposito, Susanna; Grohmann, Ursula
Amino acid metabolism in rheumatoid arthritis: Friend or foe? 1-gen-2020 Panfili, E.; Gerli, R.; Grohmann, U.; Pallotta, M. T.