IRIS - Res&Arch Institutional Research Information System - Research & Archive

GRIGNANI, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 3.351
EU - Europa 2.495
AS - Asia 1.870
SA - Sud America 337
AF - Africa 63
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.123
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Nazione #
US - Stati Uniti d'America 3.260
SG - Singapore 886
UA - Ucraina 509
SE - Svezia 362
IE - Irlanda 358
IT - Italia 304
RU - Federazione Russa 270
CN - Cina 266
BR - Brasile 259
VN - Vietnam 190
DE - Germania 188
HK - Hong Kong 176
FI - Finlandia 142
FR - Francia 120
KR - Corea 98
GB - Regno Unito 97
IN - India 46
CA - Canada 45
BD - Bangladesh 37
TR - Turchia 35
AR - Argentina 31
MX - Messico 28
PL - Polonia 22
ZA - Sudafrica 21
BE - Belgio 18
CH - Svizzera 17
RO - Romania 17
SA - Arabia Saudita 16
UZ - Uzbekistan 16
AT - Austria 14
VE - Venezuela 14
IQ - Iraq 13
NL - Olanda 13
JP - Giappone 12
EC - Ecuador 10
ES - Italia 10
LB - Libano 10
PK - Pakistan 10
GR - Grecia 8
LT - Lituania 8
PH - Filippine 8
AE - Emirati Arabi Uniti 7
CL - Cile 6
EG - Egitto 6
JM - Giamaica 6
KE - Kenya 6
MY - Malesia 6
TN - Tunisia 6
BO - Bolivia 5
CZ - Repubblica Ceca 5
ID - Indonesia 5
JO - Giordania 5
MA - Marocco 5
OM - Oman 5
PY - Paraguay 5
CO - Colombia 4
CR - Costa Rica 4
ET - Etiopia 4
KZ - Kazakistan 4
AU - Australia 3
DZ - Algeria 3
SY - Repubblica araba siriana 3
AZ - Azerbaigian 2
BG - Bulgaria 2
BH - Bahrain 2
CI - Costa d'Avorio 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
HU - Ungheria 2
IL - Israele 2
IR - Iran 2
KG - Kirghizistan 2
NA - Namibia 2
NZ - Nuova Zelanda 2
RS - Serbia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CD - Congo 1
CG - Congo 1
CM - Camerun 1
GE - Georgia 1
GN - Guinea 1
HN - Honduras 1
LV - Lettonia 1
LY - Libia 1
MK - Macedonia 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
QA - Qatar 1
SI - Slovenia 1
SN - Senegal 1
SR - Suriname 1
Totale 8.118
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Città #
Singapore 592
Chandler 461
Dublin 358
San Jose 271
Jacksonville 253
Ashburn 182
Hong Kong 175
San Mateo 169
Boardman 139
Santa Clara 123
Altamura 117
Seoul 98
Perugia 96
Ann Arbor 93
Medford 89
Princeton 89
Dong Ket 82
Lawrence 79
Lauterbourg 78
Munich 78
Beijing 76
Moscow 76
Wilmington 75
New York 74
The Dalles 61
Los Angeles 50
Des Moines 47
Andover 44
Helsinki 40
Piscataway 40
Ho Chi Minh City 37
Hanoi 30
Columbus 27
Orem 23
São Paulo 21
Woodbridge 20
Warsaw 18
Brussels 17
Bucharest 17
Denver 17
Turku 17
Brooklyn 16
Norwalk 16
Montreal 15
Izmir 14
Saint Petersburg 14
Dhaka 13
Ottawa 13
Johannesburg 12
Rio de Janeiro 12
Tokyo 12
Poplar 11
San Paolo di Civitate 11
Stockholm 11
Dallas 10
Mexico City 10
Rome 10
Shanghai 10
Chennai 9
Chicago 9
Houston 9
Ankara 8
Falls Church 8
Manchester 8
Boston 7
Charlotte 7
Frankfurt am Main 7
London 7
Amsterdam 6
Auburn Hills 6
Barnet 6
Belo Horizonte 6
Jeddah 6
Riyadh 6
Atlanta 5
Bologna 5
Brno 5
Campinas 5
Curitiba 5
Da Nang 5
Mumbai 5
New Delhi 5
Nuremberg 5
Phoenix 5
Quito 5
Salvador 5
San Francisco 5
Tashkent 5
Toronto 5
Addis Ababa 4
Amman 4
Baghdad 4
Bengaluru 4
Città Di Castello 4
Goiânia 4
Jackson 4
Lahore 4
Las Vegas 4
Lausanne 4
Milan 4
Totale 4.893
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Nome #
Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells. 156
Effect of the acute promyelocytic leukemia PML/RAR alpha protein on differentiation and survival of myeloid precursors. 153
Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells. 150
Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism 148
Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response 139
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation 137
Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. 133
Prognostic Role of Circulating miRNAs in Early-Stage Non-Small Cell Lung Cancer 128
N-(4-Hydroxyphenyl) retinamide Induces Apoptosis of Malignant Hemopoietic Cell Lines Including Those Unresponsive to Retinoic Acid. 127
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. 125
Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells. 122
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis 117
Caspases mediate RA-induced degradation of acute promyelocytic leukemia PML/RARa fusion protein 117
Acute Promyelocytic Leukemia: from genetics to treatment. 117
Cooperation between RING+B1-B2 and coiled-coil domains of PML is necesary for its effects on cell growth 117
Acute promyelocytic leukemia cells resistant to retinoic acid show further perturbation of the RARa signal transduction system. 115
Down regulation of LFA-I adhesion receptor by the c-myc oncogene in human B-lymphoblastoid cells 114
Btg2 Enhances Retinoic Acid Induced Differentiation By Modulating Histone H4 Methylation And Acetylation 113
C-MYB activation and the pathogenesis of ovarian cancer. 111
Histone deacetylase recruitment by RARa fusion proteins in promyelocytic leukemia 111
Cellular localization and tissue distribution of PML proteins as defined by a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product. Preferential expression in postmitotic cells. 110
The acute promyelocytic leukaemia specific PML/RARa fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. 110
DeltaN-p73 is a transcriptional target of the PML/RARalpha oncogene in myeloid differentiation. 110
Pathogenetic Relevance Of The Acute Promyelocytic Leukemia-Specific PML/RARa Fusion Protein 109
Characterization of the PML/RARa chimeric product of the acute promyelocytic leukemia specific t(15;17) translocation. 107
In vitro response to all trans Retinoic acid of acute promyelocytic leukemia with non reciprocal PML/RARa or RAR/PML fusion genes. 106
A novel trasforming protein with a SH2 domain is implicated in mitogenic signal transduction. 102
Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis. 101
Low brachial artery flow-mediated dilation predicts worse prognosis in hospitalized patients with covid-19 101
Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis. 100
Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity. 99
Myelomonocytic-associated antigens in a case of genotypically, phenotypically and functionally B-cell lymphoma. 99
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression. 98
Effects on differentiation by the promyelocytic leukemia PML/RARa protein depend on the fusion of the PML protein-dimerization and RARa DNA binding domains. 97
Molecular Pathogenesis of Acute Promyelocytic Leukaemia. 97
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis 97
Efficient infection and selection of hematopoietic progenitors by a novel GFP based retroviral vector 96
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia 96
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 93
Cell death induction by the acute promyelocytic leukemia specific PML/RARa fusion protein. 93
Human CD4 lymphocytes recognize a peptide representing the fusion region of the hybrid protein PML/RARa present in acute promyelocytic leukemia cells. 92
PML is required for telomere stability in non-neoplastic human cells 92
Targeting the KRAS variant for treatment of non-small cell lung cancer: Potential therapeutic applications 92
Negative autoregulation of c-myc expression is inactivated in trasformed cells 90
Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors. 90
Terminal megakaryocytic differentiationof TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARa fusion protein. 89
Opposite effects of Acute promyelocytic leukemia PML/RARa and PLZF/RARa fusion proteins on retinoic acid signalling. 89
Molecular Genetics Of The T(15;17) Of Acute Promyelocytic Leukemia 87
Circadian metabolic adaptations to infections 84
Infrequent alteration of the RARa gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leukemias, myelodysplastic syndromes and cell lines. 84
Transcriptional targeting by microRNA-Polycomb complexes: a novel route in cell fate determination 84
MiRNAs and resistance to EGFRâ€"TKIs in EGFR-mutant non-small cell lung cancer: Beyond 'traditional mechanisms' of resistance 84
The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. 83
Biological and Clinical developments in cancer vaccines 82
Identification of DNA rearrangements at the RAR-a locus in all patients with acute promyelocytic leukemia (APL) and mapping of APL breakpoints within the RAR-a second intron 81
DNA damage and cell death in human oral squamous cell carcinoma cells: The potential biological effects of cannabidiol 80
Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors. 79
Vaccini antitumorali: novità biologiche e cliniche. 77
The molecular genetics of acute promyelocytic leukemia 77
Retinoid -induced differentiation of acute promyelocytic leukemia involves PML/RARa-mediated increase of type II transglutaminase. 75
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane 74
Gene regulation in normal and leukaemic progenitor/stem cells. 72
High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. 71
Epigenetic role of miRNAs in normal and leukemic hematopoiesis. 71
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 70
Molecular genetics of the t(15;17) of acute promyelocytic leukemia (APPL). 70
Structure and origin of the acute promyelocityc leukaemia MYL/RARa cDNA and characterization of its retinoid binding and transactivation properties 68
Growth and Tumor Promoting Effects of Deregulated Bcl-2 in Human B Lymphoblastoid Cells 67
PML/RARa fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype 67
Molecular biology of acute promyelocytic leukemia 67
PCSK9 and cancer: Rethinking the link 67
Thyroid function tests in patients undergoing maintenance dialysis: characterization of the 'low-T4 syndrome' in subjects on regular hemodialysis and continuous ambulatory peritoneal dialysis. 66
Promyelocytic leukemia specific PML-retinoic acid receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells. 65
Pathogenetic role of the PML1RAR alpha fusion protein in acute promyelocytic leukemia. 65
Impaired differentiation of U937 cell mutants expressing the PML/RARa fusion protein is unblocked by retinoic acid. 64
Occurrence of Resistance to Retinoic Acid in the Acute Promyelocytic Leukemia Cell Line NB4 Is Associated With Altered Expression of the PMLRARa Protein. 63
Systemic lupus erythematosus following total body irradiation for malignant lymphoma. 63
Genetic lesions disrupting calreticulin 3'-untranslated region in JAK2 mutation-negative polycythemia vera 62
In vitro transcription and translation inhibition by anti-PML/RARa and PML peptide nucleic acid (PNA). 61
The PML/RARa fusion protein inhibits TNFa-induced apoptosis in U937 cells and in acute promyelocytic leukemia blasts. 61
Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. 59
Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells 58
The localization of the HRX proteinto specific nuclear subomains is altered by fusion with its eps15 translocation partner 58
The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies. 58
The promyelocytic leukemia (PML) gene product is a cellular target of the adenovirus E1A protein and functionally interacts with the retinoblastoma protein. 57
The molecular genetics of acute promyelocytic leukemia. 57
Molecular biology of lymphoid malignancies. 54
Genetics of APL and the molecular basis of retinoic acid treatment. 54
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. 53
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 52
RARs and microRNAs 52
Mechanism of negative feed-back regulation of c-myc gene expression in B-cells and its inactivation in tumor cells. 47
The acute promyelocytic leukemia PML/RARa protein affects differentiation and survival of myeloid precursor cells 43
The impact of external stimuli on the acquisition of robotic surgery skills: the Im-AcRoSS study 9
Totale 8.307
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Categoria #
all - tutte 36.343
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.343
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022739 21 109 30 64 30 6 8 222 12 21 90 126
2022/20231.447 97 283 25 108 134 200 0 58 480 4 45 13
2023/2024441 35 60 23 8 15 9 83 6 44 6 91 61
2024/20251.188 24 130 109 32 117 50 36 78 229 70 201 112
2025/20262.667 206 161 97 384 404 221 457 169 255 236 49 28
2026/202722 22 0 0 0 0 0 0 0 0 0 0 0
Totale 8.307