IRIS - Res&Arch Institutional Research Information System - Research & Archive

GRIGNANI, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 2.836
EU - Europa 2.280
AS - Asia 1.444
SA - Sud America 249
AF - Africa 26
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.840
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Nazione #
US - Stati Uniti d'America 2.768
SG - Singapore 689
UA - Ucraina 507
SE - Svezia 360
IE - Irlanda 357
IT - Italia 283
CN - Cina 238
BR - Brasile 220
RU - Federazione Russa 192
DE - Germania 186
HK - Hong Kong 170
FI - Finlandia 139
VN - Vietnam 134
KR - Corea 98
GB - Regno Unito 84
FR - Francia 38
CA - Canada 37
TR - Turchia 27
MX - Messico 23
PL - Polonia 22
BE - Belgio 18
CH - Svizzera 17
RO - Romania 17
AR - Argentina 15
IN - India 15
AT - Austria 14
BD - Bangladesh 13
NL - Olanda 12
JP - Giappone 10
ES - Italia 9
LB - Libano 9
UZ - Uzbekistan 9
ZA - Sudafrica 9
LT - Lituania 8
GR - Grecia 7
AE - Emirati Arabi Uniti 6
BO - Bolivia 5
CZ - Repubblica Ceca 5
KE - Kenya 5
DZ - Algeria 3
EC - Ecuador 3
IQ - Iraq 3
SA - Arabia Saudita 3
AZ - Azerbaigian 2
CL - Cile 2
CR - Costa Rica 2
ID - Indonesia 2
IL - Israele 2
IR - Iran 2
JO - Giordania 2
KZ - Kazakistan 2
MA - Marocco 2
NA - Namibia 2
NZ - Nuova Zelanda 2
PH - Filippine 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AU - Australia 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
CD - Congo 1
CG - Congo 1
CI - Costa d'Avorio 1
CO - Colombia 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
LV - Lettonia 1
MK - Macedonia 1
NO - Norvegia 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
PK - Pakistan 1
PY - Paraguay 1
SN - Senegal 1
SV - El Salvador 1
TH - Thailandia 1
VE - Venezuela 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 6.840
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Città #
Chandler 460
Singapore 433
Dublin 357
Jacksonville 252
Hong Kong 170
San Mateo 169
Boardman 139
Ashburn 134
Santa Clara 119
Altamura 117
Seoul 98
Ann Arbor 93
Perugia 90
Medford 89
Princeton 89
Dong Ket 82
Lawrence 79
Munich 78
Beijing 76
Wilmington 74
New York 68
Des Moines 47
Los Angeles 45
Andover 44
Piscataway 40
Helsinki 37
Moscow 36
Columbus 27
Ho Chi Minh City 24
Woodbridge 20
São Paulo 19
Warsaw 18
Brussels 17
Bucharest 17
Denver 17
Turku 17
Norwalk 16
Hanoi 15
Brooklyn 14
Izmir 14
Saint Petersburg 14
The Dalles 14
Ottawa 13
Montreal 12
Poplar 11
San Paolo di Civitate 11
Mexico City 10
Orem 10
Rio de Janeiro 10
Shanghai 10
Tokyo 10
Houston 9
Johannesburg 9
Rome 9
Stockholm 9
Falls Church 8
Ankara 7
Boston 7
Chennai 7
Manchester 7
Auburn Hills 6
Belo Horizonte 6
Dallas 6
London 6
Amsterdam 5
Brno 5
Charlotte 5
Chicago 5
Curitiba 5
Frankfurt am Main 5
Nuremberg 5
San Francisco 5
Atlanta 4
Bologna 4
Campinas 4
Città Di Castello 4
Dhaka 4
Goiânia 4
Jackson 4
Lausanne 4
Nairobi 4
Phoenix 4
Seattle 4
Toronto 4
Bexley 3
Campo Grande 3
Carapicuíba 3
Chapecó 3
Falkenstein 3
Hefei 3
Mumbai 3
Paris 3
Pelotas 3
Philadelphia 3
Querétaro 3
Redwood City 3
Riyadh 3
Rondonópolis 3
San Diego 3
Secaucus 3
Totale 4.107
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Nome #
Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells. 136
Effect of the acute promyelocytic leukemia PML/RAR alpha protein on differentiation and survival of myeloid precursors. 130
Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism 124
Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response 121
Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells. 114
Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. 113
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation 113
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. 110
Prognostic Role of Circulating miRNAs in Early-Stage Non-Small Cell Lung Cancer 109
Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells. 106
N-(4-Hydroxyphenyl) retinamide Induces Apoptosis of Malignant Hemopoietic Cell Lines Including Those Unresponsive to Retinoic Acid. 105
Cooperation between RING+B1-B2 and coiled-coil domains of PML is necesary for its effects on cell growth 104
Acute promyelocytic leukemia cells resistant to retinoic acid show further perturbation of the RARa signal transduction system. 99
Acute Promyelocytic Leukemia: from genetics to treatment. 99
Down regulation of LFA-I adhesion receptor by the c-myc oncogene in human B-lymphoblastoid cells 97
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis 96
Caspases mediate RA-induced degradation of acute promyelocytic leukemia PML/RARa fusion protein 96
The acute promyelocytic leukaemia specific PML/RARa fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. 95
Btg2 Enhances Retinoic Acid Induced Differentiation By Modulating Histone H4 Methylation And Acetylation 95
Histone deacetylase recruitment by RARa fusion proteins in promyelocytic leukemia 94
Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis. 93
Characterization of the PML/RARa chimeric product of the acute promyelocytic leukemia specific t(15;17) translocation. 90
In vitro response to all trans Retinoic acid of acute promyelocytic leukemia with non reciprocal PML/RARa or RAR/PML fusion genes. 90
C-MYB activation and the pathogenesis of ovarian cancer. 90
Cellular localization and tissue distribution of PML proteins as defined by a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product. Preferential expression in postmitotic cells. 89
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression. 89
Molecular Pathogenesis of Acute Promyelocytic Leukaemia. 89
Myelomonocytic-associated antigens in a case of genotypically, phenotypically and functionally B-cell lymphoma. 88
DeltaN-p73 is a transcriptional target of the PML/RARalpha oncogene in myeloid differentiation. 88
Effects on differentiation by the promyelocytic leukemia PML/RARa protein depend on the fusion of the PML protein-dimerization and RARa DNA binding domains. 87
Human CD4 lymphocytes recognize a peptide representing the fusion region of the hybrid protein PML/RARa present in acute promyelocytic leukemia cells. 85
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia 84
Pathogenetic Relevance Of The Acute Promyelocytic Leukemia-Specific PML/RARa Fusion Protein 84
Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis. 83
A novel trasforming protein with a SH2 domain is implicated in mitogenic signal transduction. 82
Negative autoregulation of c-myc expression is inactivated in trasformed cells 81
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis 81
PML is required for telomere stability in non-neoplastic human cells 81
Terminal megakaryocytic differentiationof TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARa fusion protein. 80
Efficient infection and selection of hematopoietic progenitors by a novel GFP based retroviral vector 80
Targeting the KRAS variant for treatment of non-small cell lung cancer: Potential therapeutic applications 79
Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors. 78
Low brachial artery flow-mediated dilation predicts worse prognosis in hospitalized patients with covid-19 77
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 76
Cell death induction by the acute promyelocytic leukemia specific PML/RARa fusion protein. 75
The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. 75
Infrequent alteration of the RARa gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leukemias, myelodysplastic syndromes and cell lines. 74
Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity. 74
Vaccini antitumorali: novità biologiche e cliniche. 72
Opposite effects of Acute promyelocytic leukemia PML/RARa and PLZF/RARa fusion proteins on retinoic acid signalling. 71
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane 70
Biological and Clinical developments in cancer vaccines 69
Identification of DNA rearrangements at the RAR-a locus in all patients with acute promyelocytic leukemia (APL) and mapping of APL breakpoints within the RAR-a second intron 69
Transcriptional targeting by microRNA-Polycomb complexes: a novel route in cell fate determination 69
Molecular Genetics Of The T(15;17) Of Acute Promyelocytic Leukemia 68
MiRNAs and resistance to EGFRâ€"TKIs in EGFR-mutant non-small cell lung cancer: Beyond 'traditional mechanisms' of resistance 68
The molecular genetics of acute promyelocytic leukemia 67
Retinoid -induced differentiation of acute promyelocytic leukemia involves PML/RARa-mediated increase of type II transglutaminase. 65
Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors. 65
Epigenetic role of miRNAs in normal and leukemic hematopoiesis. 64
Circadian metabolic adaptations to infections 63
Molecular biology of acute promyelocytic leukemia 62
Gene regulation in normal and leukaemic progenitor/stem cells. 61
Structure and origin of the acute promyelocityc leukaemia MYL/RARa cDNA and characterization of its retinoid binding and transactivation properties 60
PML/RARa fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype 60
High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. 59
Occurrence of Resistance to Retinoic Acid in the Acute Promyelocytic Leukemia Cell Line NB4 Is Associated With Altered Expression of the PMLRARa Protein. 58
Growth and Tumor Promoting Effects of Deregulated Bcl-2 in Human B Lymphoblastoid Cells 58
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 58
In vitro transcription and translation inhibition by anti-PML/RARa and PML peptide nucleic acid (PNA). 57
Promyelocytic leukemia specific PML-retinoic acid receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells. 56
Impaired differentiation of U937 cell mutants expressing the PML/RARa fusion protein is unblocked by retinoic acid. 55
Thyroid function tests in patients undergoing maintenance dialysis: characterization of the 'low-T4 syndrome' in subjects on regular hemodialysis and continuous ambulatory peritoneal dialysis. 55
Molecular genetics of the t(15;17) of acute promyelocytic leukemia (APPL). 54
Pathogenetic role of the PML1RAR alpha fusion protein in acute promyelocytic leukemia. 54
The PML/RARa fusion protein inhibits TNFa-induced apoptosis in U937 cells and in acute promyelocytic leukemia blasts. 53
PCSK9 and cancer: Rethinking the link 53
Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells 52
The molecular genetics of acute promyelocytic leukemia. 52
The localization of the HRX proteinto specific nuclear subomains is altered by fusion with its eps15 translocation partner 51
The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies. 51
Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. 50
Systemic lupus erythematosus following total body irradiation for malignant lymphoma. 49
The promyelocytic leukemia (PML) gene product is a cellular target of the adenovirus E1A protein and functionally interacts with the retinoblastoma protein. 48
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. 48
Molecular biology of lymphoid malignancies. 48
DNA damage and cell death in human oral squamous cell carcinoma cells: The potential biological effects of cannabidiol 48
Genetic lesions disrupting calreticulin 3'-untranslated region in JAK2 mutation-negative polycythemia vera 47
Genetics of APL and the molecular basis of retinoic acid treatment. 46
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 45
Mechanism of negative feed-back regulation of c-myc gene expression in B-cells and its inactivation in tumor cells. 41
The acute promyelocytic leukemia PML/RARa protein affects differentiation and survival of myeloid precursor cells 38
RARs and microRNAs 38
Totale 7.023
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Categoria #
all - tutte 31.590
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.590
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021464 0 0 0 0 0 63 72 1 110 37 83 98
2021/2022739 21 109 30 64 30 6 8 222 12 21 90 126
2022/20231.447 97 283 25 108 134 200 0 58 480 4 45 13
2023/2024441 35 60 23 8 15 9 83 6 44 6 91 61
2024/20251.188 24 130 109 32 117 50 36 78 229 70 201 112
2025/20261.405 206 161 97 384 404 153 0 0 0 0 0 0
Totale 7.023