IRIS - Res&Arch Institutional Research Information System - Research & Archive

GRIGNANI, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 3.383
EU - Europa 2.446
AS - Asia 1.833
SA - Sud America 338
Continente sconosciuto - Info sul continente non disponibili 179
AF - Africa 61
OC - Oceania 5
Totale 8.245
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Nazione #
US - Stati Uniti d'America 3.275
SG - Singapore 861
UA - Ucraina 497
SE - Svezia 359
IE - Irlanda 351
IT - Italia 296
CN - Cina 265
RU - Federazione Russa 264
BR - Brasile 259
DE - Germania 185
VN - Vietnam 185
HK - Hong Kong 178
FI - Finlandia 138
FR - Francia 118
GB - Regno Unito 96
KR - Corea 96
CA - Canada 55
IN - India 45
BD - Bangladesh 37
TR - Turchia 33
AR - Argentina 31
MX - Messico 27
PL - Polonia 21
ZA - Sudafrica 20
BE - Belgio 18
CH - Svizzera 17
RO - Romania 17
SA - Arabia Saudita 17
UZ - Uzbekistan 15
AT - Austria 14
VE - Venezuela 14
IQ - Iraq 13
NL - Olanda 13
JP - Giappone 12
EC - Ecuador 10
LB - Libano 10
PK - Pakistan 10
JM - Giamaica 9
ES - Italia 8
GR - Grecia 8
LT - Lituania 8
CL - Cile 7
PH - Filippine 7
AE - Emirati Arabi Uniti 6
EG - Egitto 6
TN - Tunisia 6
CO - Colombia 5
CZ - Repubblica Ceca 5
ID - Indonesia 5
JO - Giordania 5
KE - Kenya 5
MA - Marocco 5
MY - Malesia 5
OM - Oman 5
PY - Paraguay 5
BO - Bolivia 4
CR - Costa Rica 4
ET - Etiopia 4
KZ - Kazakistan 4
AU - Australia 3
DZ - Algeria 3
HN - Honduras 3
SY - Repubblica araba siriana 3
AZ - Azerbaigian 2
BG - Bulgaria 2
BH - Bahrain 2
CI - Costa d'Avorio 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
IL - Israele 2
IR - Iran 2
KG - Kirghizistan 2
NA - Namibia 2
NZ - Nuova Zelanda 2
RS - Serbia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BY - Bielorussia 1
CD - Congo 1
CG - Congo 1
CM - Camerun 1
GD - Grenada 1
GE - Georgia 1
GN - Guinea 1
GP - Guadalupe 1
GT - Guatemala 1
LV - Lettonia 1
LY - Libia 1
MK - Macedonia 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
Totale 8.059
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Città #
Singapore 571
Chandler 452
Dublin 351
San Jose 263
Jacksonville 249
Ashburn 199
Hong Kong 177
San Mateo 165
Boardman 136
Santa Clara 124
Altamura 113
Seoul 96
Ann Arbor 92
Medford 87
Princeton 87
Perugia 85
Dong Ket 82
New York 81
Beijing 78
Lawrence 77
Munich 77
Lauterbourg 76
Moscow 76
Wilmington 72
The Dalles 61
Los Angeles 53
Des Moines 44
Piscataway 44
Andover 42
Helsinki 40
Ho Chi Minh City 36
Hanoi 29
Columbus 26
Orem 23
São Paulo 22
Montreal 20
Woodbridge 20
Brussels 17
Bucharest 17
Denver 17
Warsaw 17
Brooklyn 16
Norwalk 16
Turku 15
Izmir 14
Saint Petersburg 14
Dhaka 13
Ottawa 13
Dallas 12
Johannesburg 12
Rome 12
Tokyo 12
Poplar 11
Rio de Janeiro 11
San Paolo di Civitate 11
Stockholm 11
Chicago 10
Houston 10
Shanghai 10
Chennai 9
Mexico City 9
Phoenix 9
Manchester 8
Ankara 7
Boston 7
Charlotte 7
Frankfurt am Main 7
London 7
Amsterdam 6
Auburn Hills 6
Da Nang 6
Jeddah 6
Milan 6
Riyadh 6
San Francisco 6
Toronto 6
Atlanta 5
Barnet 5
Belo Horizonte 5
Bologna 5
Brno 5
Buffalo 5
Campinas 5
Curitiba 5
Kingston 5
Mumbai 5
Nuremberg 5
Quito 5
Salvador 5
Addis Ababa 4
Amman 4
Baghdad 4
Bengaluru 4
Città Di Castello 4
Goiânia 4
Jackson 4
Lahore 4
Las Vegas 4
Lausanne 4
Nairobi 4
Totale 4.844
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Nome #
Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells. 159
Effect of the acute promyelocytic leukemia PML/RAR alpha protein on differentiation and survival of myeloid precursors. 154
Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism 148
Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response 139
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation 138
Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. 136
N-(4-Hydroxyphenyl) retinamide Induces Apoptosis of Malignant Hemopoietic Cell Lines Including Those Unresponsive to Retinoic Acid. 130
Prognostic Role of Circulating miRNAs in Early-Stage Non-Small Cell Lung Cancer 128
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. 127
Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells. 125
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis 121
Acute Promyelocytic Leukemia: from genetics to treatment. 120
Cooperation between RING+B1-B2 and coiled-coil domains of PML is necesary for its effects on cell growth 119
Caspases mediate RA-induced degradation of acute promyelocytic leukemia PML/RARa fusion protein 117
Acute promyelocytic leukemia cells resistant to retinoic acid show further perturbation of the RARa signal transduction system. 116
C-MYB activation and the pathogenesis of ovarian cancer. 116
Down regulation of LFA-I adhesion receptor by the c-myc oncogene in human B-lymphoblastoid cells 115
Btg2 Enhances Retinoic Acid Induced Differentiation By Modulating Histone H4 Methylation And Acetylation 115
The acute promyelocytic leukaemia specific PML/RARa fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. 114
Histone deacetylase recruitment by RARa fusion proteins in promyelocytic leukemia 113
DeltaN-p73 is a transcriptional target of the PML/RARalpha oncogene in myeloid differentiation. 113
Cellular localization and tissue distribution of PML proteins as defined by a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product. Preferential expression in postmitotic cells. 112
Efficient infection and selection of hematopoietic progenitors by a novel GFP based retroviral vector 110
Pathogenetic Relevance Of The Acute Promyelocytic Leukemia-Specific PML/RARa Fusion Protein 110
Characterization of the PML/RARa chimeric product of the acute promyelocytic leukemia specific t(15;17) translocation. 109
In vitro response to all trans Retinoic acid of acute promyelocytic leukemia with non reciprocal PML/RARa or RAR/PML fusion genes. 107
A novel trasforming protein with a SH2 domain is implicated in mitogenic signal transduction. 103
Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis. 103
Low brachial artery flow-mediated dilation predicts worse prognosis in hospitalized patients with covid-19 103
Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis. 102
Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity. 100
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia 100
Myelomonocytic-associated antigens in a case of genotypically, phenotypically and functionally B-cell lymphoma. 100
Molecular Pathogenesis of Acute Promyelocytic Leukaemia. 99
Effects on differentiation by the promyelocytic leukemia PML/RARa protein depend on the fusion of the PML protein-dimerization and RARa DNA binding domains. 98
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression. 98
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis 97
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 95
PML is required for telomere stability in non-neoplastic human cells 95
Human CD4 lymphocytes recognize a peptide representing the fusion region of the hybrid protein PML/RARa present in acute promyelocytic leukemia cells. 93
Cell death induction by the acute promyelocytic leukemia specific PML/RARa fusion protein. 93
Targeting the KRAS variant for treatment of non-small cell lung cancer: Potential therapeutic applications 93
Terminal megakaryocytic differentiationof TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARa fusion protein. 92
Negative autoregulation of c-myc expression is inactivated in trasformed cells 91
Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors. 91
Opposite effects of Acute promyelocytic leukemia PML/RARa and PLZF/RARa fusion proteins on retinoic acid signalling. 89
Molecular Genetics Of The T(15;17) Of Acute Promyelocytic Leukemia 88
Infrequent alteration of the RARa gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leukemias, myelodysplastic syndromes and cell lines. 86
Circadian metabolic adaptations to infections 85
Biological and Clinical developments in cancer vaccines 85
Transcriptional targeting by microRNA-Polycomb complexes: a novel route in cell fate determination 85
DNA damage and cell death in human oral squamous cell carcinoma cells: The potential biological effects of cannabidiol 85
MiRNAs and resistance to EGFRâ€"TKIs in EGFR-mutant non-small cell lung cancer: Beyond 'traditional mechanisms' of resistance 84
Identification of DNA rearrangements at the RAR-a locus in all patients with acute promyelocytic leukemia (APL) and mapping of APL breakpoints within the RAR-a second intron 83
The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. 83
Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors. 80
The molecular genetics of acute promyelocytic leukemia 78
Vaccini antitumorali: novità biologiche e cliniche. 77
Retinoid -induced differentiation of acute promyelocytic leukemia involves PML/RARa-mediated increase of type II transglutaminase. 77
Gene regulation in normal and leukaemic progenitor/stem cells. 74
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane 74
High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. 72
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 71
Molecular genetics of the t(15;17) of acute promyelocytic leukemia (APPL). 71
Epigenetic role of miRNAs in normal and leukemic hematopoiesis. 71
Structure and origin of the acute promyelocityc leukaemia MYL/RARa cDNA and characterization of its retinoid binding and transactivation properties 69
Promyelocytic leukemia specific PML-retinoic acid receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells. 69
PML/RARa fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype 69
Growth and Tumor Promoting Effects of Deregulated Bcl-2 in Human B Lymphoblastoid Cells 68
Molecular biology of acute promyelocytic leukemia 68
Pathogenetic role of the PML1RAR alpha fusion protein in acute promyelocytic leukemia. 67
PCSK9 and cancer: Rethinking the link 67
Thyroid function tests in patients undergoing maintenance dialysis: characterization of the 'low-T4 syndrome' in subjects on regular hemodialysis and continuous ambulatory peritoneal dialysis. 66
Occurrence of Resistance to Retinoic Acid in the Acute Promyelocytic Leukemia Cell Line NB4 Is Associated With Altered Expression of the PMLRARa Protein. 65
Impaired differentiation of U937 cell mutants expressing the PML/RARa fusion protein is unblocked by retinoic acid. 65
Systemic lupus erythematosus following total body irradiation for malignant lymphoma. 64
Genetic lesions disrupting calreticulin 3'-untranslated region in JAK2 mutation-negative polycythemia vera 63
The PML/RARa fusion protein inhibits TNFa-induced apoptosis in U937 cells and in acute promyelocytic leukemia blasts. 62
Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells 61
Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. 60
The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies. 60
The localization of the HRX proteinto specific nuclear subomains is altered by fusion with its eps15 translocation partner 58
The promyelocytic leukemia (PML) gene product is a cellular target of the adenovirus E1A protein and functionally interacts with the retinoblastoma protein. 58
The molecular genetics of acute promyelocytic leukemia. 57
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. 55
Genetics of APL and the molecular basis of retinoic acid treatment. 55
Molecular biology of lymphoid malignancies. 54
RARs and microRNAs 54
Natural killer cell-mediated lysis of autologous cells modified by gene therapy 52
Mechanism of negative feed-back regulation of c-myc gene expression in B-cells and its inactivation in tumor cells. 47
The acute promyelocytic leukemia PML/RARa protein affects differentiation and survival of myeloid precursor cells 44
The impact of external stimuli on the acquisition of robotic surgery skills: the Im-AcRoSS study 13
Totale 8.245
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Categoria #
all - tutte 37.345
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.345
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022584 0 0 29 64 26 1 8 215 8 21 89 123
2022/20231.417 95 275 25 108 131 193 0 57 472 4 44 13
2023/2024431 35 59 22 8 15 9 81 6 44 6 88 58
2024/20251.164 24 127 108 32 112 50 36 77 225 68 197 108
2025/20262.591 202 157 93 374 392 218 436 167 248 230 47 27
2026/2027171 39 72 60 0 0 0 0 0 0 0 0 0
Totale 8.245