PUXEDDU, Efisio
 Distribuzione geografica
Continente #
NA - Nord America 5.045
EU - Europa 4.091
AS - Asia 3.662
SA - Sud America 702
AF - Africa 83
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 8
Totale 13.600
Nazione #
US - Stati Uniti d'America 4.930
SG - Singapore 1.658
UA - Ucraina 725
SE - Svezia 565
BR - Brasile 552
IE - Irlanda 522
RU - Federazione Russa 497
FR - Francia 494
IT - Italia 491
CN - Cina 460
HK - Hong Kong 450
VN - Vietnam 422
DE - Germania 268
KR - Corea 213
FI - Finlandia 198
BD - Bangladesh 114
GB - Regno Unito 111
IN - India 64
AR - Argentina 45
IQ - Iraq 42
TR - Turchia 42
MX - Messico 41
CA - Canada 40
BE - Belgio 32
PK - Pakistan 28
CH - Svizzera 27
NL - Olanda 27
CO - Colombia 26
AT - Austria 25
PL - Polonia 25
UZ - Uzbekistan 25
ID - Indonesia 21
ZA - Sudafrica 21
EC - Ecuador 20
SA - Arabia Saudita 20
JP - Giappone 18
VE - Venezuela 16
PY - Paraguay 15
RO - Romania 14
ES - Italia 12
CZ - Repubblica Ceca 10
GR - Grecia 10
MA - Marocco 10
CL - Cile 9
IL - Israele 9
LB - Libano 9
PH - Filippine 9
BG - Bulgaria 8
EU - Europa 8
BO - Bolivia 7
KE - Kenya 7
MY - Malesia 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
AU - Australia 6
EG - Egitto 6
KZ - Kazakistan 6
LT - Lituania 6
UY - Uruguay 6
AO - Angola 5
CR - Costa Rica 5
DZ - Algeria 5
HN - Honduras 5
JM - Giamaica 5
KG - Kirghizistan 5
NP - Nepal 5
PA - Panama 4
SN - Senegal 4
AL - Albania 3
AM - Armenia 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
JO - Giordania 3
MD - Moldavia 3
NI - Nicaragua 3
OM - Oman 3
PE - Perù 3
PT - Portogallo 3
QA - Qatar 3
RS - Serbia 3
SY - Repubblica araba siriana 3
TH - Thailandia 3
AZ - Azerbaigian 2
BY - Bielorussia 2
CI - Costa d'Avorio 2
GA - Gabon 2
GT - Guatemala 2
LK - Sri Lanka 2
LU - Lussemburgo 2
LY - Libia 2
NG - Nigeria 2
PS - Palestinian Territory 2
SR - Suriname 2
SV - El Salvador 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BB - Barbados 1
BF - Burkina Faso 1
BH - Bahrain 1
BZ - Belize 1
Totale 13.579
Città #
Singapore 1.159
Chandler 721
Dublin 522
San Jose 471
Hong Kong 449
Jacksonville 404
San Mateo 285
Ashburn 250
Dong Ket 243
Boardman 235
Santa Clara 207
Seoul 194
Moscow 155
Medford 151
Princeton 147
Lauterbourg 142
Altamura 126
Perugia 122
Wilmington 122
Ann Arbor 104
Beijing 103
Lawrence 97
Andover 94
Piscataway 85
Munich 84
Los Angeles 68
New York 66
Ho Chi Minh City 62
Hanoi 44
São Paulo 40
Helsinki 39
Woodbridge 39
Saint Petersburg 38
The Dalles 38
Des Moines 35
Brussels 32
Rome 30
Turku 28
Redmond 27
Shanghai 26
Dallas 25
Auburn Hills 23
Council Bluffs 23
Falls Church 23
Orem 23
Tashkent 20
Chennai 19
Frankfurt am Main 19
Norwalk 19
Baghdad 18
Chicago 18
Tokyo 18
London 17
San Paolo di Civitate 17
Atlanta 15
Phoenix 15
Denver 14
Johannesburg 14
Brasília 13
Brooklyn 13
Curitiba 13
Milan 13
Nuremberg 13
Warsaw 13
Bucharest 12
Columbus 12
Guangzhou 12
Houston 12
Lahore 12
Medellín 12
Rio de Janeiro 12
Toronto 12
Belo Horizonte 11
Da Nang 11
Amsterdam 10
Boston 10
Redwood City 10
San Francisco 10
Bologna 9
Buffalo 9
Falkenstein 9
Izmir 9
Lausanne 9
Mexico City 9
Naples 9
Vienna 9
Fremont 8
Jeddah 8
Quito 8
Charlotte 7
Dhaka 7
Karbala 7
Montreal 7
Recife 7
Stockholm 7
Asunción 6
Den Haag 6
Guarulhos 6
Lappeenranta 6
Limeira 6
Totale 8.028
Nome #
A useful ultrasound score to select thyroid nodules requiring fine needle aspiration in an iodine-deficient area. 178
Aspirato con ago sottile dei noduli tiroidei: striscio convenzionale vs preparato in strato sottile. 173
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif 149
Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF). 147
Analisi del proteoma di carcinomi papillari della tiroide positivi per la mutazione BRAFV600E 146
A usefull ultrasound score to select thyroid nodules requiring FNA in an iodine area 137
. Indoleamine 2,3-dioxygenase expression in papillary thyroid carcinoma : study of its correlation with tumor genetics and clinical behaviour 136
BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism 132
BRAF(V600E) mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas. 132
Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties. 128
Analisi del meccanismo dominante inibitorio esercitato in cis dalle mutazioni inattivanti D594V e G596R sulla mutazione attivante di BRAF V600E 127
Timing of breakfast does not influence therapeutic efficacy of liquid levothyroxine formulation 125
Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon? 121
B-RAF activating mutations inhibit genes related to intrathyroidal iodine metabolism in papillary thyroid carcinoma 120
Androgen Receptor Mutations in Prostate Cancer 120
The role of BRAF V6ooE in regulating the expression of proangiogenic factors in papillary thyroid carcinomas : in vivo and in vitro analysis. 118
Etiopatogenesi dei carcinomi della tiroide che originano dall’epitelio follicolare 117
Espressione di MKP-1 nei noduli iperplastici, adenomi e carcinomi papillari della tiroide. 115
Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer 115
Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature. 114
L’ecografia intraoperatoria nella chirurgia delle recidive del cancro differenziato della tiroide. 113
Analisi della espressione degli oncogeni RET/PTC e del proto-oncogene RET in una coorte di carcinomi papillari della tiroide sporadici e correlazione con le caratteristiche clinico-patologiche delle neoplasie 113
INSL4 as prognostic marker for proliferation and invasiveness in non-small-cell lung cancer 111
Primitive thyroid lymphomas 111
Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors 111
Search of ret/ptc rearrangement and braf and ras mutations in a umbrian papillary thyroid carcinoma cohort showed high prevalence of braf mutation and allowed to detect a new mutation of braf oncoprotein 110
Identification of differentially expressed proteins in papillary thyroid carcinomas with V600E mutation of BRAF 110
Fine needle aspiration cytology of thyroid nodules: conventional smears vs thin layer technique 110
Medicina molecolare in chirurgia della tiroide 109
Revisione della casistica dei pazienti affetti da oftalmopatia basedowiana seguiti presso il Dipartimento di Medicina Interna dell’Università degli Studi di Perugia negli anni 1990-2007 108
Caratterizzazione biochimica e molecolare della nuova mutazione BRAFV599Ins recentemente individuata in un carcinoma papillare della tiroide 108
BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas 107
The Stone Guest: How Does pH Affect Binding Properties of PD-1/PD-L1 Inhibitors? 107
Wnt/B-catenin activation and TP53 mutations associate with distinct immune profiles in advanced thyroid cancer 106
Surgical treatment of intrathyroid metastases: preliminary results of a multicentric study 106
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer 106
Severe spruelike enteropathy due to olmesartan 106
Anti-htert sirna-loaded nanoparticles block the growth of anaplastic thyroid cancer xenograft 106
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif. 105
Molecular dynamic simulations of the catalytic domain of BRAF in response to activating and inactivating mutations 104
Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation 104
A combined approach for thyroid fine needle aspiration: liquid based cytology, cell block and immunohistochemical methods with the implementation of the Cellient™ automated cell block system 103
Proteomic analysis of papillary thyroid carcinoma reveals demodulation of mechanisms regulating cell proliferation, susceptibility to oxidative stress and cellular aggregation 103
The aryl hydrocarbon receptor is expressed in thyroid carcinoma and appears to mediate epithelial-mesenchymal-transition 103
Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency 101
BRAF mutations and RET/PTC rearrangements in an italian thyroid tumor cohort 101
Surgical treatment of sporadic medullary thyroid carcinoma: strategy and outcome. 100
L’analisi proteomica del carcinoma papillare della tiroide evidenzia modificazioni dello stato ossidoriduttivo e della struttura delle cellule tumorali 99
I tumori della tiroide 99
Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity. 98
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 98
Are Evidence-Based Guidelines Reflected in Clinical Practice? An Analysis of Prospectively Collected Data of the Italian Thyroid Cancer Observatory 97
Clinical implications of BRAF mutation in thyroid carcinoma 96
Braf mutation testing in fnac samples increases accuracy of thyroid cytology in a region of high braf mutation prevalence 96
8th edition of the AJCC/TNM staging system of thyroid cancer: what to expect (ITCO#2) 95
Aspetti di biologia molecolare degli ipertiroidismi 94
Immunohistochemical analisis of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in papillary thyroid carcinoma (PYC): a marker of lymph node metastasis. 93
Sunitinib inhibits tumor vascularity and growth but does not affect Akt and ERK phosphorylation in xenograft tumors. 93
Association between BRAF V600E mutation and recurrence of papillary thyroid cancer 93
Recurrence of thyroid well differentiated cancer: ultrasonography-guided surgical treatment 92
Le sostituzioni aminoacidiche G596R e D594V hanno un effetto inibitorio dominante sulla funzione della mutazione V600E di BRAF 91
Surgical treatment of primitive thyroid lymphoma 91
B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression. 91
Liver alcoholic cirrhosis and spur-cell (acanthocytic) anaemia. A study of erythrocyte ghost composition and fluidity 90
Intracellular Signal Transduction and Modification of the Tumor Microenvironment Induced by RET/PTCs in Papillary Thyroid Carcinoma 90
Signal transducer and activator of transcription 1 plays a pivotal role in RET/PTC3 oncogene-induced expression of indoleamine 2,3-dioxygenase 1 90
Surgical treatment of medullary thyroid carcinoma (MTC) 89
Acromegaly is associated with increased cancer risk: a survey in Italy 89
Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma. 89
Patogenesi del carcinoma della tiroide 87
Characterization of novel non-clonal intrachromosomal rearrangements between the H4 and PTEN genes (H4/PTEN) in human thyroid cell lines and papillary thyroid cancer specimens 87
EFFETTO DI DUE INIBITORI CHINASICI IN LINEE CELLULARI DI CARCINOMA TIROIDEO: STUDI IN VITRO E IN VIVO 87
Conditional expression of RET/PTC3 in PCCL3 cells induces microsomal Prostaglandin E Synthase expression and Prostaglandin E2 biosynthesis through the activation of MEK-ERK pathway 86
La mutazione V599E dell’oncogene BRAF rappresenta l’alterazione genetica più frequente nei carcinomi papillari della tiroide sporadici dell’adulto 86
The 2009 American Thyroid Association Guidelines for management of thyroid nodules and differentiated thyroid cancer: progress on the road from consensus- to evidence-based practice. 86
Epigenetics of thyroid cancer and novel therapeutic targets. 86
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells 84
Diagnostic-therapeutic pathways as instruments of clinical management: experience at the S. Maria Hospital in Terni 83
Oncogeni e chirurgia della tiroide 83
Confronto tra citologia aspirativa con ago sottile e parametri eco-color-doppler nei noduli tiroidei 83
Ret/PTC activation does not influence clinical and pathological features of adult papillary thyroid carcinomas. 83
Comparison between fine needle aspiration cytology and ultrasound features in thyroid nodules: an US score to select thyroid nodules requiring FNA. 82
Caratteristiche genetiche di una coorte di carcinomi papillari della tiroide raccolta in Umbria e loro significato clinico 82
Germline BRAF mutations in Noonan, LEOPARD and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum 82
Evaluation of goiter using ultrasound criteria: a survey in a middle schoolchildren population of a mountain area in Central Italy. 82
Acute liver damage following intravenous glucocorticoid treatment for Graves’ ophthalmopathy 81
Clinical prognosis in BRAF-mutated PTC 81
Isozyme-specific abnormalities of protein kinase C in thyroid cancer: evidence for epigenetic changes in PKC epsilon 79
Proteomic analysis of papillary thyroid carcinomas reveals demodulation of signal transduction pathways, increased resistance to oxidative stress and gain of invasive phenotype. 79
Microsomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway 79
Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer. 79
THERAPY of ENDOCRINE DISEASE Immunotherapy of advanced thyroid cancer: From bench to bedside 79
Molecular dynamic simulation of the catalytic domain of BRAF in response to activating and inactivating mutation 78
Surgical treatment of differenziated thyroid carcinoma: a retrospective study 78
Sunitinib inhibits the growth of thyroid tumor xenografts in mice by acting primarily on tumor angiogenesis 76
Sunitinib exerts only limited effects on the proliferation and differentiation of anaplastic thyroid cancer cells 76
A Prospective Multicenter Study Examining the Relationship Between Thyroid Cancer Treatment Outcomes and the Presence of Autoimmune Thyroiditis 75
Lo studio dell’espressione genica indotta da RET/PTC nella linea cellulare PCCL3 evidenzia l’attivazione precoce di geni coinvolti nella regolazione della risposta immunitaria. 75
Search of RET/PTC rearrangement and BRAF and RAS mutations in a umbrian papillary thyroid carcinoma cohort showed high prevalence of BRAF mutation and allowed to detect a new mutation of BRAF oncoprotein 75
Modifications in the Papillary Thyroid Cancer Gene Profile Over the Last 15 Years. 75
Totale 10.099
Categoria #
all - tutte 59.283
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.283


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021275 0 0 0 0 0 0 0 0 0 0 0 275
2021/20221.247 36 215 35 113 31 8 18 397 6 49 139 200
2022/20232.106 179 394 30 193 178 206 2 110 710 21 68 15
2023/2024853 57 106 33 18 20 6 155 28 159 25 123 123
2024/20252.088 24 218 99 98 228 79 49 201 448 132 332 180
2025/20264.505 351 347 233 567 513 370 708 257 551 396 135 77
Totale 13.912