CAROSATI, Emanuele
CAROSATI, Emanuele
DIPARTIMENTO DI CHIMICA, BIOLOGIA E BIOTECNOLOGIE
1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs
2011 Ioan, P; Carosati, Emanuele; Micucci, M; Cruciani, Gabriele; Broccatelli, Fabio; Zhorov, Bs; Chiarini, A; Budriesi, R.
1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets
2012 Carosati, Emanuele; P., Ioan; M., Micucci; Broccatelli, Fabio; Cruciani, Gabriele; B. S., Zhorov; A., Chiarini; R., Budriesi
A new class of selective myocardial calcium channel modulators. 2. Role of the acetal chain in oxadiazol-3-one derivatives.
2005 Budriesi, R.; Carosati, Emanuele; Chiarini, A.; Cosimelli, B.; Cruciani, Gabriele; Ioan, P.; Spinelli, D.; Spisani, R.
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump
2012 Sabatini, Stefano; Gosetto, Francesca; Manfroni, Giuseppe; Tabarrini, Oriana; Carosati, Emanuele; Cecchetti, Violetta
A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields
2011 Broccatelli, Fabio; Carosati, Emanuele; A., Neri; M., Frosini; Goracci, Laura; T. I., Oprea; Cruciani, Gabriele
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects
2012 P., Ioan; A., Ciogli; Sirci, Francesco; R., Budriesi; B., Cosimelli; M., Pierini; E., Severi; A., Chiarini; Cruciani, Gabriele; F., Gasparrini; D., Spinelli; Carosati, Emanuele
ADME-Space: A new tool for medicinal chemists to explore ADME properties
2017 Bocci, Giovanni; Carosati, Emanuele; Vayer, Philippe; Arrault, Alban; Lozano, Sylvain; Cruciani, Gabriele
Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type K-ATP channel openers
2005 Carosati, Emanuele; Lemoine, H.; Spogli, Roberto; Grittner, D.; Mannhold, R.; Tabarrini, Oriana; Sabatini, Stefano; Cecchetti, Violetta
Calcium channel antagonists discovered by a multidisciplinary approach
2006 Carosati, Emanuele; Cruciani, Gabriele; Chiarini, A.; Budriesi, R.; Ioan, P.; Spisani, R.; Cosimelli, B.; Fusi, F.; Frosini, M.; Matucci, R.; Gasparrini, F.; Ciogli, A.; Stephens, P.; Devlin, F.
Characterization of Protein-Binding Sites and Ligands Using Molecular Interaction Fields
2007 Cruciani, Gabriele; Carosati, Emanuele; Wade, R.; Baroni, Massimo
Discovery of Novel and Cardioselective Diltiazem-like Calcium Channel Blockers via Virtual Screening
2008 Carosati, Emanuele; Budriesi, R.; Ioan, P.; Ugenti, M. P.; Frosini, M.; Fusi, F.; Corda, G.; Cosimelli, B.; Spinelli, D.; Chiarini, A.; Cruciani, Gabriele
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus.
2011 Brincat, JEAN PIERRE; Carosati, Emanuele; Sabatini, Stefano; Manfroni, Giuseppe; Fravolini, Arnaldo; Raygada, Jl; Patel, D; Kaatz, Gw; Cruciani, Gabriele
Discovery of Novel, Potent, and Specific Cell-Death Inducers in the Jurkat Acute Lymphoblastic Leukemia Cell Line
2015 Carosati, Emanuele; Van Den Höfel, Natascha; Reif, Manuela; Randazzo, GIUSEPPE MARCO; Stanitzki, Bettina; Stevens, Julia; Gabbert, Helmut E.; Cruciani, Gabriele; Mannhold, Raimund; Mahotka, Csaba
FLAP: GRID Molecular Interaction Fields in Virtual Screening. Validation using the DUD Data Set
2010 S., Cross; Baroni, Massimo; Carosati, Emanuele; Benedetti, Paolo; Clementi, Sergio
From 6-Aminoquinolone Antibacterials to 6-Amino-7-thiopyranopyridinylquinolone Ethyl Esters as Inhibitors of Staphylococcus aureus Multidrug Efflux Pumps.
2010 Pieroni, Marco; M., Dimovska; Brincat, JEAN PIERRE; Sabatini, Stefano; Carosati, Emanuele; Massari, Serena; G. W., Kaatz; Fravolini, Arnaldo
Homodimeric enzymes as drug targets
2010 Cardinale, D; SALO AHEN, O. M. H.; Ferrari, S; Ponterini, G; Cruciani, Gabriele; Carosati, Emanuele; Tochowicz, A. M.; Mangani, S; Wade, R. C.; Costi, M. P.
Hydrogen Bonding Interactions of Covalently-Bonded Fluorine Atoms: From Crystallographic Data to a New Angular Function in the GRID Force Field
2004 Carosati, Emanuele; Sciabola, Simone; Cruciani, Gabriele
IAP antagonists: promising candidates for cancer therapy
2010 R., Mannhold; S., Fulda; Carosati, Emanuele
Inhibitor of Ovarian Cancer Cells Growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase
2012 Carosati, Emanuele; Tochowicz, A.; Marverti, G.; Guaitoli, G.; Benedetti, Paolo; Ferrari, S.; Stroud, R. M.; Finer Moore, J.; Luciani, R.; Farina, D.; Cruciani, Gabriele; Costi, M. P.
Integrating Crystallography into Early Metabolism Studies
2009 Cruciani, Gabriele; Aristei, Yasmin; Goracci, Laura; Carosati, Emanuele
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs | 2011 | Ioan, P; Carosati, Emanuele; Micucci, M; Cruciani, Gabriele; Broccatelli, Fabio; Zhorov, Bs; Chiarini, A; Budriesi, R. | |
| 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets | 2012 | Carosati, Emanuele; P., Ioan; M., Micucci; Broccatelli, Fabio; Cruciani, Gabriele; B. S., Zhorov; A., Chiarini; R., Budriesi | |
| A new class of selective myocardial calcium channel modulators. 2. Role of the acetal chain in oxadiazol-3-one derivatives. | 2005 | Budriesi, R.; Carosati, Emanuele; Chiarini, A.; Cosimelli, B.; Cruciani, Gabriele; Ioan, P.; Spinelli, D.; Spisani, R. | |
| A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump | 2012 | Sabatini, Stefano; Gosetto, Francesca; Manfroni, Giuseppe; Tabarrini, Oriana; Carosati, Emanuele; Cecchetti, Violetta | |
| A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields | 2011 | Broccatelli, Fabio; Carosati, Emanuele; A., Neri; M., Frosini; Goracci, Laura; T. I., Oprea; Cruciani, Gabriele | |
| Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects | 2012 | P., Ioan; A., Ciogli; Sirci, Francesco; R., Budriesi; B., Cosimelli; M., Pierini; E., Severi; A., Chiarini; Cruciani, Gabriele; F., Gasparrini; D., Spinelli; Carosati, Emanuele | |
| ADME-Space: A new tool for medicinal chemists to explore ADME properties | 2017 | Bocci, Giovanni; Carosati, Emanuele; Vayer, Philippe; Arrault, Alban; Lozano, Sylvain; Cruciani, Gabriele | |
| Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type K-ATP channel openers | 2005 | Carosati, Emanuele; Lemoine, H.; Spogli, Roberto; Grittner, D.; Mannhold, R.; Tabarrini, Oriana; Sabatini, Stefano; Cecchetti, Violetta | |
| Calcium channel antagonists discovered by a multidisciplinary approach | 2006 | Carosati, Emanuele; Cruciani, Gabriele; Chiarini, A.; Budriesi, R.; Ioan, P.; Spisani, R.; Cosimelli, B.; Fusi, F.; Frosini, M.; Matucci, R.; Gasparrini, F.; Ciogli, A.; Stephens, P.; Devlin, F. | |
| Characterization of Protein-Binding Sites and Ligands Using Molecular Interaction Fields | 2007 | Cruciani, Gabriele; Carosati, Emanuele; Wade, R.; Baroni, Massimo | |
| Discovery of Novel and Cardioselective Diltiazem-like Calcium Channel Blockers via Virtual Screening | 2008 | Carosati, Emanuele; Budriesi, R.; Ioan, P.; Ugenti, M. P.; Frosini, M.; Fusi, F.; Corda, G.; Cosimelli, B.; Spinelli, D.; Chiarini, A.; Cruciani, Gabriele | |
| Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. | 2011 | Brincat, JEAN PIERRE; Carosati, Emanuele; Sabatini, Stefano; Manfroni, Giuseppe; Fravolini, Arnaldo; Raygada, Jl; Patel, D; Kaatz, Gw; Cruciani, Gabriele | |
| Discovery of Novel, Potent, and Specific Cell-Death Inducers in the Jurkat Acute Lymphoblastic Leukemia Cell Line | 2015 | Carosati, Emanuele; Van Den Höfel, Natascha; Reif, Manuela; Randazzo, GIUSEPPE MARCO; Stanitzki, Bettina; Stevens, Julia; Gabbert, Helmut E.; Cruciani, Gabriele; Mannhold, Raimund; Mahotka, Csaba | |
| FLAP: GRID Molecular Interaction Fields in Virtual Screening. Validation using the DUD Data Set | 2010 | S., Cross; Baroni, Massimo; Carosati, Emanuele; Benedetti, Paolo; Clementi, Sergio | |
| From 6-Aminoquinolone Antibacterials to 6-Amino-7-thiopyranopyridinylquinolone Ethyl Esters as Inhibitors of Staphylococcus aureus Multidrug Efflux Pumps. | 2010 | Pieroni, Marco; M., Dimovska; Brincat, JEAN PIERRE; Sabatini, Stefano; Carosati, Emanuele; Massari, Serena; G. W., Kaatz; Fravolini, Arnaldo | |
| Homodimeric enzymes as drug targets | 2010 | Cardinale, D; SALO AHEN, O. M. H.; Ferrari, S; Ponterini, G; Cruciani, Gabriele; Carosati, Emanuele; Tochowicz, A. M.; Mangani, S; Wade, R. C.; Costi, M. P. | |
| Hydrogen Bonding Interactions of Covalently-Bonded Fluorine Atoms: From Crystallographic Data to a New Angular Function in the GRID Force Field | 2004 | Carosati, Emanuele; Sciabola, Simone; Cruciani, Gabriele | |
| IAP antagonists: promising candidates for cancer therapy | 2010 | R., Mannhold; S., Fulda; Carosati, Emanuele | |
| Inhibitor of Ovarian Cancer Cells Growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase | 2012 | Carosati, Emanuele; Tochowicz, A.; Marverti, G.; Guaitoli, G.; Benedetti, Paolo; Ferrari, S.; Stroud, R. M.; Finer Moore, J.; Luciani, R.; Farina, D.; Cruciani, Gabriele; Costi, M. P. | |
| Integrating Crystallography into Early Metabolism Studies | 2009 | Cruciani, Gabriele; Aristei, Yasmin; Goracci, Laura; Carosati, Emanuele |