To exploit the potential of lipid nanoparticles (LNs) as theranostic agent. To this aim, a series of preliminary evaluations were performed: Formulation optimization, rheological analysis to evaluate syringeability and injectability, long-term stability, acute toxicity and teratogenicity, and in vivo evaluation of brain targeting.
Lipid nanoparticles for theranostic applications
BLASI, PAOLO;ALBERTINI, BARBARA;SCHOUBBEN, Aurelie Marie Madeleine;RICCI, Maurizio;
2014
Abstract
To exploit the potential of lipid nanoparticles (LNs) as theranostic agent. To this aim, a series of preliminary evaluations were performed: Formulation optimization, rheological analysis to evaluate syringeability and injectability, long-term stability, acute toxicity and teratogenicity, and in vivo evaluation of brain targeting.File in questo prodotto:
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