This paper analyzes the communications and medical potentials arising from establishing nano-scale communications making use of the stent tubular structures in blood vessels. Most of stent implants (both bare metal and drug eluiting stents) happens in coronary arteries for supporting weak endothelial points and counteracting the obstructing effects of arthrosclerosis. Such structures have continuously inspired researchers for introducing additional functions to the mere mechanical sustain of vessels. After a review of the current literature, we propose an original use of stents for monitoring CD47 receptors bearing cells and provide effective diagnostic and prognostic information. We can also perform the detection of different cancer markers, and then integrate this information. These monitoring functions and the event notifications makes used of nano-scale communications. Through a well established simulator of biological nano-scale communications, we will gain significant insights about the establishment of these types of communications happening between different sections of the stent structure. The information exchanges is assumed to be collected by nano-sensors of tumor cells. The outcome of the research is the characterization of the channel transmission capabilities. When considering cost benefit of these expensive smart stents, we suggest a wider perspective where oncologists may join the team of future interventional cardiologists. Thus, our system creates a link between cancer detection, stent devices, and body area networks to P5 medicine.

Endovascular Mobile Sensor Network for Detecting Circulating Tumoral Cells

FELICETTI, LUCA;FEMMINELLA, Mauro;REALI, Gianluca;
2014

Abstract

This paper analyzes the communications and medical potentials arising from establishing nano-scale communications making use of the stent tubular structures in blood vessels. Most of stent implants (both bare metal and drug eluiting stents) happens in coronary arteries for supporting weak endothelial points and counteracting the obstructing effects of arthrosclerosis. Such structures have continuously inspired researchers for introducing additional functions to the mere mechanical sustain of vessels. After a review of the current literature, we propose an original use of stents for monitoring CD47 receptors bearing cells and provide effective diagnostic and prognostic information. We can also perform the detection of different cancer markers, and then integrate this information. These monitoring functions and the event notifications makes used of nano-scale communications. Through a well established simulator of biological nano-scale communications, we will gain significant insights about the establishment of these types of communications happening between different sections of the stent structure. The information exchanges is assumed to be collected by nano-sensors of tumor cells. The outcome of the research is the characterization of the channel transmission capabilities. When considering cost benefit of these expensive smart stents, we suggest a wider perspective where oncologists may join the team of future interventional cardiologists. Thus, our system creates a link between cancer detection, stent devices, and body area networks to P5 medicine.
2014
978-1-63190-047-1
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1287951
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