tA series of ultrastructural-based studies were conducted on the interface region in differentfish–helminth systems: (a) an intestinal infection of the cestode Monobothrium wageneri intench, Tinca tinca; (b) an extensive intestinal submucosa and mucosal infection in tench bymetacercariae of an unidentified digenean trematode; (c) an intestinal infection in browntrout, Salmo trutta, by the acanthocephalan Dentitruncus truttae; (d) an extraintestinal infec-tion by larvae of the acanthocephalan, Pomphorhynchus laevis in three-spined sticklebacks,Gasterosteus aculeatus; and (e) an infection in the livers of Eurasian minnow, Phoxinus phoxi-nus, by larvae of the nematode Raphidascaris acus. Endoparasitic helminths frequently causeinflammation of the digestive tract and associated organs, inducing the recruitment of var-ious immune cells to the site of infection. In each of the fish–helminth systems that werestudied, a massive hyperplastic granulocyte response involving mast cells (MCs) and neu-trophils in close proximity to the helminths was documented. The current study presentsdata on the interface region in each fish–helminth system and documents the penetrationof mast cells granules within the tegument of P. laevis larvae. No extracellular vesicles con-taining tegumental secretions from any of the four different taxa of endoparasitic helminthsspecies at the host–parasite interface region were seen.

Fine structure and cellular responses at the host-parasite interface in a range of fish-helminth systems

LORENZONI, Massimo;
2015

Abstract

tA series of ultrastructural-based studies were conducted on the interface region in differentfish–helminth systems: (a) an intestinal infection of the cestode Monobothrium wageneri intench, Tinca tinca; (b) an extensive intestinal submucosa and mucosal infection in tench bymetacercariae of an unidentified digenean trematode; (c) an intestinal infection in browntrout, Salmo trutta, by the acanthocephalan Dentitruncus truttae; (d) an extraintestinal infec-tion by larvae of the acanthocephalan, Pomphorhynchus laevis in three-spined sticklebacks,Gasterosteus aculeatus; and (e) an infection in the livers of Eurasian minnow, Phoxinus phoxi-nus, by larvae of the nematode Raphidascaris acus. Endoparasitic helminths frequently causeinflammation of the digestive tract and associated organs, inducing the recruitment of var-ious immune cells to the site of infection. In each of the fish–helminth systems that werestudied, a massive hyperplastic granulocyte response involving mast cells (MCs) and neu-trophils in close proximity to the helminths was documented. The current study presentsdata on the interface region in each fish–helminth system and documents the penetrationof mast cells granules within the tegument of P. laevis larvae. No extracellular vesicles con-taining tegumental secretions from any of the four different taxa of endoparasitic helminthsspecies at the host–parasite interface region were seen.
2015
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1317500
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