The hydrogel obtained by a zwitterionic N-oxide surfactant is proposed as the core of a pH-responsive artificial gland model. The viscosity and pH variations, induced by pulse additions of acid and base, are investigated by a pyridinium salt and alizarin red S, respectively. The artificial gland model is implemented by enclosing the gel within a dialysis membrane, and its secretory action is tested by monitoring the release of a fluorescent acridinium salt.
Mimicking the Secretory Action of a Gland by a Composite System Made of a pH-Responsive Surfactant-Based Hydrogel and a Dialysis Membrane
Cesaretti, Alessio;Di Guida, Irene;Clementi, Catia;Germani, Raimondo;Gentili, Pier Luigi
2018
Abstract
The hydrogel obtained by a zwitterionic N-oxide surfactant is proposed as the core of a pH-responsive artificial gland model. The viscosity and pH variations, induced by pulse additions of acid and base, are investigated by a pyridinium salt and alizarin red S, respectively. The artificial gland model is implemented by enclosing the gel within a dialysis membrane, and its secretory action is tested by monitoring the release of a fluorescent acridinium salt.File in questo prodotto:
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