During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons for this success. Here, we document the advances in the biology and in the innovative biotechnological applications of ASCs. We discuss how the multipotential property boosts ASCs toward mesenchymal and non-mesenchymal differentiation cell lineages and how their character is maintained even if they are combined with gene delivery systems and/or biomaterials, both in vitro and in vivo.

Adipose stem cell translational applications: From bench-to-bedside

Argentati, Chiara
Writing – Original Draft Preparation
;
Morena, Francesco
Writing – Original Draft Preparation
;
Bazzucchi, Martina
Investigation
;
Armentano, Ilaria
Investigation
;
Emiliani, Carla
Resources
;
Martino, Sabata
Supervision
2018

Abstract

During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons for this success. Here, we document the advances in the biology and in the innovative biotechnological applications of ASCs. We discuss how the multipotential property boosts ASCs toward mesenchymal and non-mesenchymal differentiation cell lineages and how their character is maintained even if they are combined with gene delivery systems and/or biomaterials, both in vitro and in vivo.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1441379
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