Phase II trials have shown encouraging activity with ipilimumab plus fotemustine and ipilimumab plus nivolumab in melanoma brain metastases. We report the primary analysis and four-year follow-up of the NIBIT-M2 study, the first phase III trial comparing these regimens to fotemustine in melanoma patients with brain metastases.
Primary analysis and four-year follow-up of the phase III NIBIT-M2 trial in melanoma patients with brain metastases
Ferrucci, Pier Francesco;Mandala', Mario;
2021
Abstract
Phase II trials have shown encouraging activity with ipilimumab plus fotemustine and ipilimumab plus nivolumab in melanoma brain metastases. We report the primary analysis and four-year follow-up of the NIBIT-M2 study, the first phase III trial comparing these regimens to fotemustine in melanoma patients with brain metastases.File in questo prodotto:
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