The complexity of molecular communications system, involving a massive number of interacting entities, makes scalability a fundamental property of simulators and modeling tools. A typical scenario is that of targeted drug delivery systems, which makes use of biological nanoma-chines close to a biological target, able to release molecules in the diseased area. In this paper, we propose a simple although reliable receiver model for diffusion-based molecular communication systems tackling the time needed for analyzing such a system. The proposed model consists of using an equivalent markovian queuing model, which reproduces the aggregate behavior of thousands of receptors spread over the receiver surface. It takes into account not only the fact that the absorption of molecules can occur only through receptors, but also that absorption is not an instantaneous process, and may require a significant time during which the receptor is not available to bind to other molecules. Our results, expressed in terms of number of absorbed molecules and average number of busy receptors, demonstrate that the proposed approach is in good agreement with results obtained through particle-based simulations of a large number of receptors, although the time taken for obtaining the results with the proposed model is order of magnitudes lower than the simulation time. We believe that this model can be the precursor of novel class of models based on similar principles that allow realizing reliable simulations of much larger systems.

A simple queuing model for molecular communications receivers

Femminella M.
Conceptualization
;
Reali G.
Writing – Review & Editing
2021-01-01

Abstract

The complexity of molecular communications system, involving a massive number of interacting entities, makes scalability a fundamental property of simulators and modeling tools. A typical scenario is that of targeted drug delivery systems, which makes use of biological nanoma-chines close to a biological target, able to release molecules in the diseased area. In this paper, we propose a simple although reliable receiver model for diffusion-based molecular communication systems tackling the time needed for analyzing such a system. The proposed model consists of using an equivalent markovian queuing model, which reproduces the aggregate behavior of thousands of receptors spread over the receiver surface. It takes into account not only the fact that the absorption of molecules can occur only through receptors, but also that absorption is not an instantaneous process, and may require a significant time during which the receptor is not available to bind to other molecules. Our results, expressed in terms of number of absorbed molecules and average number of busy receptors, demonstrate that the proposed approach is in good agreement with results obtained through particle-based simulations of a large number of receptors, although the time taken for obtaining the results with the proposed model is order of magnitudes lower than the simulation time. We believe that this model can be the precursor of novel class of models based on similar principles that allow realizing reliable simulations of much larger systems.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1538357
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