Our previous chemical constituent study of Pinus dalatensis and Pinus krempfii had identified six compounds 1-6. The continuing investigation of biological activity of the conifer species led to discovery of the antiproliferative activity of all isolated compounds 1-6 on acute myeloid leukemia cells as shown by the effects on cell cycle progression. Remarkably, compound 3 (chrysin) exibited potent bioactivity at the concentration of 10 μg/mL.
Antiproliferative activity of isolated compounds from Pinus dalatensis and Pinus krempfii on acute myeloid Leukemia cells
Adorisio S.;Delfino D. V.;
2019
Abstract
Our previous chemical constituent study of Pinus dalatensis and Pinus krempfii had identified six compounds 1-6. The continuing investigation of biological activity of the conifer species led to discovery of the antiproliferative activity of all isolated compounds 1-6 on acute myeloid leukemia cells as shown by the effects on cell cycle progression. Remarkably, compound 3 (chrysin) exibited potent bioactivity at the concentration of 10 μg/mL.File in questo prodotto:
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