Short Bowel Syndrome (SBS) is a malabsorption syndrome characterized by a severe reduction of the absorbent surface of the intestinal mucosa. Treatment of this condition needs multi-professional teams and different therapies, which are not always enough to ensure enteral autonomy. New techniques are being explored, particularly distraction enterogenesis, which can allow the lengthening of the residual intestines of these patients. This study aims to demonstrate the possibility of using biocompatible and biodegradable materials to design ingestible capsules which carry 3D-printed springs capable of reaching the patient’s intestine. These devices can be used as a slightly invasive distraction enterogenesis technique, stimulating cell proliferation and intestinal elongation without surgery.
Ingestible capsules carrying 3D printed springs to treat Short Bowel Syndrome with Distraction Enterogenesis
Luca ValentiniInvestigation
;
2023
Abstract
Short Bowel Syndrome (SBS) is a malabsorption syndrome characterized by a severe reduction of the absorbent surface of the intestinal mucosa. Treatment of this condition needs multi-professional teams and different therapies, which are not always enough to ensure enteral autonomy. New techniques are being explored, particularly distraction enterogenesis, which can allow the lengthening of the residual intestines of these patients. This study aims to demonstrate the possibility of using biocompatible and biodegradable materials to design ingestible capsules which carry 3D-printed springs capable of reaching the patient’s intestine. These devices can be used as a slightly invasive distraction enterogenesis technique, stimulating cell proliferation and intestinal elongation without surgery.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
