The present study investigates the post-arthroscopic use of xylazine as intra-articular (IA) analgesic in the horse. Thirty-two horses referred for arthroscopy were randomly assigned to 3 groups which differed for the treatment received IA at the end of surgery: xylazine 1 mg/kg, morphine 0.1 mg/kg, saline. All treatment were administered in a final volume of 10 mL. Recovery quality and times were scored, as well as post-operative clinical evaluation at 15, 60 and 120 minutes after recovery. Plasma concentration of xylazine was measured at regular intervals for 10 hours to verify a possible sistemic action of the drug. These preliminary results suggest a valid post arthroscopic analgesic protocol characterized by a good recovery and the absence of xylazlne related systemic effects, blocking pain at its peripheral source.
Intra-articular analgesia in the horse: post-arthroscopic use of α2 agonist. Preliminary results
NANNARONE, Sara;BAZZICA, CHIARA;BUFALARI, Antonello;GIALLETTI, Rodolfo;PEPE, Marco
2008
Abstract
The present study investigates the post-arthroscopic use of xylazine as intra-articular (IA) analgesic in the horse. Thirty-two horses referred for arthroscopy were randomly assigned to 3 groups which differed for the treatment received IA at the end of surgery: xylazine 1 mg/kg, morphine 0.1 mg/kg, saline. All treatment were administered in a final volume of 10 mL. Recovery quality and times were scored, as well as post-operative clinical evaluation at 15, 60 and 120 minutes after recovery. Plasma concentration of xylazine was measured at regular intervals for 10 hours to verify a possible sistemic action of the drug. These preliminary results suggest a valid post arthroscopic analgesic protocol characterized by a good recovery and the absence of xylazlne related systemic effects, blocking pain at its peripheral source.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
