Aim of the study was find a relationship between same circulating tumoral markers (CTM), alphafetoprotein (AFP), antigen cancer 15/3 (CA 15/3), carcinembryonal antigen (CEA) and neoplastic diseases in canine serum and plasma. Strenghthened chemiluminescence was used in order to determine levels of AFP, CEA and CA 15/3 in blood of three groups of animals (A healthy dogs; B dogs with non neoplastic diseases; C dogs with clear tumour lesions). CEA wasn’t measurable in all samples, whereas the results about CA 15/3 aren’t probably able to differentiate any particular group. In conclusion, the AFP is the most interesting because its levels increase during the neoplastic diseases, especially when the tumours as mastocitoma and lymphoma are extended to the liver.
Assessment and behavior of alphafetoprotein (AFP), antigen cancer 15/3 (CA 15/3), carcinembryonal antigen (CEA) in clinical oncology of the dog: preliminary study
MARCHESI, Maria Chiara;CONTI, Maria Beatrice;PIERAMATI, Camillo;MANGILI PECCI, Vittorio;FRUGANTI, Gabriele
2007
Abstract
Aim of the study was find a relationship between same circulating tumoral markers (CTM), alphafetoprotein (AFP), antigen cancer 15/3 (CA 15/3), carcinembryonal antigen (CEA) and neoplastic diseases in canine serum and plasma. Strenghthened chemiluminescence was used in order to determine levels of AFP, CEA and CA 15/3 in blood of three groups of animals (A healthy dogs; B dogs with non neoplastic diseases; C dogs with clear tumour lesions). CEA wasn’t measurable in all samples, whereas the results about CA 15/3 aren’t probably able to differentiate any particular group. In conclusion, the AFP is the most interesting because its levels increase during the neoplastic diseases, especially when the tumours as mastocitoma and lymphoma are extended to the liver.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
