The aim of this study was to evaluate the effect of constant rate local anaesthetic (lidocaine) delivery system compared to continuous intravenous (IV) morphine infusion for postoperative analgesia after total front leg amputation. All dogs, randomly divided in two groups for post surgical treatment, received the same anaesthetic protocol to perform amputation. Dogs assigned to lidocaine group (L) received a constant rate infusion of 2% lidocaine locally (2-6 mg/kg/h) and a continuous IV infusion of saline solution (equivalent volume as for morphine infusion), while dogs assigned to morphine group (M) received a continuous IV infusion of morphine (0,1 - 0,2 mg/kg/h) and a constant rate infusion of saline solution locally (equivalent volume as for lidocaine locally). Infusions in both groups lasted for 24 hours. Locally delivering of lidocaine was considered an equipotent and feasible method of postoperative analgesia compared to IV morphine after surgery. Lidocaine group dogs did required rescue analgesic as well as morphine group. Group L had a lower sedation score compared to morphine group dogs that were more sedated and manifested respiratory depression (1 dog) and dysphoria (2 dogs). No wound complications were noted in both groups.
Gestione analgesica postoperatoria mediante pompa elastomerica: considerazioni preliminari
BUFALARI, Antonello;DI MEO, Antonio;ARCELLI, Rolando;
2007
Abstract
The aim of this study was to evaluate the effect of constant rate local anaesthetic (lidocaine) delivery system compared to continuous intravenous (IV) morphine infusion for postoperative analgesia after total front leg amputation. All dogs, randomly divided in two groups for post surgical treatment, received the same anaesthetic protocol to perform amputation. Dogs assigned to lidocaine group (L) received a constant rate infusion of 2% lidocaine locally (2-6 mg/kg/h) and a continuous IV infusion of saline solution (equivalent volume as for morphine infusion), while dogs assigned to morphine group (M) received a continuous IV infusion of morphine (0,1 - 0,2 mg/kg/h) and a constant rate infusion of saline solution locally (equivalent volume as for lidocaine locally). Infusions in both groups lasted for 24 hours. Locally delivering of lidocaine was considered an equipotent and feasible method of postoperative analgesia compared to IV morphine after surgery. Lidocaine group dogs did required rescue analgesic as well as morphine group. Group L had a lower sedation score compared to morphine group dogs that were more sedated and manifested respiratory depression (1 dog) and dysphoria (2 dogs). No wound complications were noted in both groups.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
