Systemic lupus erythematosus (SLE) is an autoimmune disease mainly affecting mostly young women, potentially involving any organ/system. The central role of environmental factors in disease pathogenesis has been widely demonstrated: among these, an emerging interest has been pointed to dietary factors.1-4 In this context, the spectrum of research on caffeine, one of the most widely consumed products in the world, is exponentially growing during the last decade. Indeed, caffeine, acting as a non-specific phosphodiesterase inhibitor, seems to be able to interact with multiple components of the immune system, influencing both innate and adaptive response.5-8
The Impact of Caffeine Intake on Patients with Systemic Lupus Erythematosus: Protect Yourself, Drink More Coffee!
Perricone, Carlo;
2020
Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease mainly affecting mostly young women, potentially involving any organ/system. The central role of environmental factors in disease pathogenesis has been widely demonstrated: among these, an emerging interest has been pointed to dietary factors.1-4 In this context, the spectrum of research on caffeine, one of the most widely consumed products in the world, is exponentially growing during the last decade. Indeed, caffeine, acting as a non-specific phosphodiesterase inhibitor, seems to be able to interact with multiple components of the immune system, influencing both innate and adaptive response.5-8I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
