Development of a Musculoskeletal Model as an In-Silico Tool to Enhance Prosthesis Design in Mandibular Reconstruction

Nowadays, 3D-printed mandibular prostheses are increasingly employed following extensive bone resections and are typically designed by mirroring the contralateral healthy side. Often, design validation is based merely on assessing geometrical interference in various static positions of the mandible, overlooking the dynamic role of hard and soft tissues. This study aims to develop a multibody (MB) mandibular model to be applied in improving the design process of patient-specific prostheses by including biomechanical information, such as the estimation of range of motion, risk of dislocation, and potential overloading of anatomical structures.