Tetrabutylammonium fluoride (TBAF) is an efficient catalyst in the [3 + 2] cycloaddition reaction of organic nitriles 1 with trimethylsilyl azide (TMSN3) in solventless conditions. The corresponding 5-substituted 1Htetrazoles 2 were obtained under mild conditions and in 80- 97% yields.
TBAF-Catalyzed Synthesis of 5-Substituted 1H-Tetrazoles under Solventless Conditions
AMANTINI, David;BELEGGIA, Romina;FRINGUELLI, Francesco;PIZZO, Ferdinando;VACCARO, Luigi
2004
Abstract
Tetrabutylammonium fluoride (TBAF) is an efficient catalyst in the [3 + 2] cycloaddition reaction of organic nitriles 1 with trimethylsilyl azide (TMSN3) in solventless conditions. The corresponding 5-substituted 1Htetrazoles 2 were obtained under mild conditions and in 80- 97% yields.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
