The early detection and monitoring of inflammation is a primary challenge in veterinary medicine. The circulating concentrations of acute phase proteins may provide an objective measure of both the severity of the insult and the intensity of the inflammatory response in the horse. A clinical study on the possible role of serum amyloid A (SAA), fibrinogen and haptoglobin as inflammation markers in the horse was conducted on 40 horses, with a significant correlation emerging between the patterns of SAA concentrations and clinical assessments of the patients being monitored during their hospitalization. The results of this preliminary study support the use of SAA as an important parameter at diagnostic, prognostic and therapeutic stage. The sequential dosage of SAA levels appears to be particularly useful in the postintervention monitoring of surgical patients
Amiloide sierica A, fibrinogeno ed aptoglobina come marcatori di flogosi nel cavallo: risultati preliminari
PASSAMONTI, Fabrizio;CERCONE, MARTA;NANNARONE, Sara;BAZZICA, CHIARA;GIALLETTI, Rodolfo;DI MEO, Antonio;PEPE, Marco
2010
Abstract
The early detection and monitoring of inflammation is a primary challenge in veterinary medicine. The circulating concentrations of acute phase proteins may provide an objective measure of both the severity of the insult and the intensity of the inflammatory response in the horse. A clinical study on the possible role of serum amyloid A (SAA), fibrinogen and haptoglobin as inflammation markers in the horse was conducted on 40 horses, with a significant correlation emerging between the patterns of SAA concentrations and clinical assessments of the patients being monitored during their hospitalization. The results of this preliminary study support the use of SAA as an important parameter at diagnostic, prognostic and therapeutic stage. The sequential dosage of SAA levels appears to be particularly useful in the postintervention monitoring of surgical patientsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
