Persistent hyperglycemia can have detrimental effects on many different organs, such as the brain, heart, and endothelium. Recent human clinical trials have demonstrated a significant reduction in morbidity and mortality rate in critically ill patients when a strict glycemic control is obtained by intensive insulin therapy (regular insulin in constant-rate infusion). Considering the most important side effect of this approach (hypoglycemia), we describe the preliminary observations concerning five nondiabetic critically ill hyperglycemic cats, receiving a low dose of intermediate insulin (0.5 UI/cat SID or BID) in order to maintain the blood glucose concentration under 180 mg/dl. In our opinion, it was an efficient protocol with a proportional risk:benefit ratio.
L'insulinoterapia nel gatto non diabetico in condizioni critiche: osservazioni preliminari
CONTI, Maria Beatrice;MARCHESI, Maria Chiara;RUECA, Fabrizio
2010
Abstract
Persistent hyperglycemia can have detrimental effects on many different organs, such as the brain, heart, and endothelium. Recent human clinical trials have demonstrated a significant reduction in morbidity and mortality rate in critically ill patients when a strict glycemic control is obtained by intensive insulin therapy (regular insulin in constant-rate infusion). Considering the most important side effect of this approach (hypoglycemia), we describe the preliminary observations concerning five nondiabetic critically ill hyperglycemic cats, receiving a low dose of intermediate insulin (0.5 UI/cat SID or BID) in order to maintain the blood glucose concentration under 180 mg/dl. In our opinion, it was an efficient protocol with a proportional risk:benefit ratio.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
